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Báo cáo y học: "RNA at the steering wheel" ppsx

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Báo cáo y học: "RNA at the steering wheel" ppsx

... DNA replication, they may become distrib-uted among daughter strands in the same semiconservativeway as newly synthesized DNA [17]. In addition, modifica-tions such as methylated lysine 4 of ... interactionwas further confirmed by the finding that these RNAs alsoco-precipitate with chromatin-bound ASH1, and that the association of ASH1 with the bxd PRE/TRE is abolished byremoving single-stranded ... [13]. Assembly of the DCC presumably takes placeon nascent roX1 or 2 RNAs while they are still tethered to the DNA template on the X chromosome. From these initialnucleation sites, the DCC spreads...
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Báo cáo y học: "ahead at the potential benefits of biotechnology-derived allergen therapeutics" potx

... allergen-specific immuno-therapy. Allergen-specific immunotherapy (SIT) wasdeveloped in 1911 [4] and is the only treatment thatattends to the root cause, rather than the clinical symp-toms, of allergic ... situation may improve patient compliance with the therapeutic regime. The wait time is viewed by manypatients, as observed by experts [24], as a displeasure andmotivates some to terminate the therapeutic ... recent attention, the potential benefits of these therapeutics for improvingtherapeutic protocols, patient compliance, and broaderadministration of immunotherapy is equally attractive. At the...
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Báo cáo y học: "Chiropractic at the crossroads or are we just going around in circles" pps

... lished the “Report of the Committee ofInquiry into Chiropractic, Osteopathy, Homoeopathy andNaturopathy”, commonly called The Webb Report” [5].This government report paved the way for registrationof ... of 9 The changes had nothing to do with subluxations,rather the study identified what happens when youapply different force levels during a manipulative thrust.In other words, you may have ... ndation of the Webb Report,thirty three years ago [5], The Committee recommendsthat chiropractic and osteopathy should not be given legalrecognition in any form which would imply that they...
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Báo cáo y học: "RNA-editing-mediated exon evolution" ppsx

... mutation at the 3'ss (without deletion of the antisense Alu), respectively. The inclusion level of the Alu-exon is indicated at the top of the gel, and represents the total percentage of the ... several Alu exonization events (notincluding the NARF Alu-exon) that were hypothesized to beregulated by RNA editing; our results provide exemplary con-firmation of the validity of these predictions.It ... involved in the regulation of high efficiencyediting at the E1 site, we mutated the two nucleotides sur-rounding the edited site, as well as the nucleotide in the anti-sense Alu that is postulated...
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Báo cáo y học: "RNA polymerase II stalling: loading at the start prepares genes for a sprint" pot

... andchromatin decondensation, which enable Pol II to moveforward and transcribe a DNA template. The most commonchromatin modifications include histone acetylation by HATand methylation by HMT, ... phosphorylated [9]. The P-TEFb complex (composed of CDK9 and cyclin T) facilitates release of Pol II from stalling by phosphorylating DSIF, NELF and the carboxy-terminaldomain of Pol II at Ser2 ... (Figure 1). The P-TEFb complex includes the cyclin-dependent kinase-9(CDK9), and cyclin T. P-TEFb facilitates the release of Pol IIfrom stalling by phosphorylating DSIF, NELF and the carboxy-terminal...
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Báo cáo y học: "Association of the diplotype configuration at the N-acetyltransferase 2 gene with adverse events with co-trimoxazole in Japanese patients with systemic lupus erythematosus" pps

... ofhypersensitivity [5]. The major metabolic pathway for sulpham-ethoxazole is catalyzed by N-acetylation by N-acetyltrans-ferase 2 (NAT2). In the pathogenesis of hypersensitivity, the formation ... haplo-types exhibit the slow acetylator phenotype, whereas thosewho carry at least one wild-type haplotype exhibit the fastacetylator phenotype.In the present study we examined the association ... population,namely NAT2*4, NAT2*5B, NAT2*5E, NAT2*6A, NAT2*7Band NAT2*13. Of these, NAT2*4 is the wild-type haplotype; the remaining haplotypes are mutant types. In the presentstudy, individuals...
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Báo cáo y học: " PRDM9 points the zinc finger at meiotic recombination hotspots" potx

... (the only known H3K4 methyltransferase activity in yeast) causes dramatic changes in the pattern of hotspot usage across the yeast genome [5], suggesting that H3K4me3 is an evolutionarily conserved ... binding domain. Yet many interesting questions are unresolved. What is the molecular function of the H3K4me3 mark? What is the significance of the DNA binding specificity of PRDM9, and why is it evolving ... post-translational chromatin modification, with trimethylation of histone H3 on lysine residue 4 (H3K4me3) being a robust identifier of hotspot activity in mouse [4]. Furthermore, disruption of Set1 (the...
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Báo cáo y học: "Ethnobotany of the Monpa ethnic group at Arunachal Pradesh, India." docx

... Wanderley AG, Afiatpour P, Maia MBS:Anti-inflammatory and chronic toxicity study of the leaves of Ageratumconyzoides L. in rats. Phytomed 2005, 12:38-142.69. Murthy KS, Rao DN, Rao DK, Murthy LBS: ... remedies, they weretaken to a nearby modern health centers for further exam-ination by the physician. The ethno-bot anical knowledgeof Monpa ethnic group gathered in this study has beencategorized ... health state andgrowth of livestocks. The leaves of Cannabis sativa wasgiven to the cattle and goat to cure dysentery and diar-rhoea(Thesediseaseswereidentifiedbythepresenceofwatery stool...
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Báo cáo y học: "Factors affecting the outcome of surgically treated non-iatrogenic traumatic cervical esophageal perforation: 28 years experience at a single center" docx

... institution by another hospital. The causeof delayed treatment was delayed presentation in onepatient who had ingested a foreign body. The mortalityrate was four times higher in patients with ... patients. The overall mortality rate was 16.6% (5 patients; Table2). The mortality rate in patients with associated trachealinjuries was significantly higher than in those with no tra-Onat ... have recently attempted pri-mary repair, regardless of the interval between the injuryand intervention [15-17]. The severe contamination andinflammation that result from delayed treatment ofesophageal...
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Báo cáo y học: " Compression of the radial nerve at the elbow by a ganglion: two case reports" pot

... acompressive neuropathy of the radial sensory nerve causedby a ganglion cyst at the elbow. Orthopedics 1986, 9:1005-1006.6. Yamazaki H, Kato H, Hata Y, Murakami N, Saitoh S: The twolocations of ganglions ... Onphysical examination, a mass could not be definitelydetected by palpation. The patient had slightly decreasedsensitivity in the distribution of the sensory branch of the radial nerve. There ... different types of palsy in the radial tunnelsyndrome: posterior interosseous nerve palsy, neuropathyof the sensory branch of the radial nerve, and neuropathyof both nerves [1,3]. The posterior...
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