Báo cáo y học: "Histone H4 lysine 16 acetylation breaks the genome’s silence" pot
Báo cáo y học: "Histone H4 lysine 16 acetylation breaks the genome’s silence" pot
... H4 Lys16 acetylation studied in
different organisms. Among various acetylatable lysines iden-
tified to date, histone H4 Lys16 is functionally unique in many
ways. The special role of H4 Lys16 ... dif-
ference in the acetylation level at all the other lysine residues
(Lys5, Lys8, and Lys12) in the amino-terminal tail of histone
H4, suggesting a unique role for H4 Lys16...
Báo cáo y học: "Histone deacetylases (HDACs) in XPC gene silencing and bladder cancer" pot
... to
histone acetylation/ deacetylation, it is widely known
that the acetylation status of histones significantly
affects transcription of target genes [36]. The binding
of acetylated histones at the promoter ... in the
immunohistochemistry staining. Performance of this work was facilitated by
the Cell Culture Core, the Imaging and Flow Cytometry Core, and the
Microarray and Bi...
Báo cáo y học: "Predictors of switching antipsychotic medications in the treatment of schizophrenia" pot
... parent study protocol,
switching of the initially randomized antipsychotic was
permitted if clinically warranted [16- 18]. The objecti ves
ofthecurrentstudyweretoassessthefrequencyof
antipsychotic ... triggered by poor treatment responses
or nonadherence with the previous antipsychotic regimen
* Correspondence: haya@lilly.com
Eli Lilly and Company, Indianapolis, IN USA
Nyhuis et al. BMC...
Báo cáo y học: " Asthma and genes encoding components of the vitamin D pathway" potx
... enzymes with 25-hydroxylase activity
that catalyze the C-25 hydroxylation of vitamin D
3
. A final activation enzyme encoded by CYP27B1 subsequently catalyzes the
rate-limiting C-1 hydroxylation ...
synthesis. The later enzyme is tightly-regulated in the kidney by calcium
homeostatic signals, but also strongly induced by immune inputs (e.g. TLR signaling) in many cells of the im...
Báo cáo y học: "Mechanisms of ventilator-induced lung injury: the clinician’s perspective" docx
... hypercapnia not only may protect the lung but
also may even have its own therapeutic benefit [5]. However,
failure to increase the respiratory rate as dictated by the
ARDS Network protocol may ... in the literature
regarding the safety and efficacy of the Acute Respiratory Distress Syndrome (ARDS) Network study
protocol in reducing ventilator-induced lung injury. The issues surr...
Báo cáo y học: "Advanced directives and treatment decisions in the intensive care unit" potx
... against specific
types of treatment; it typically becomes effective only when
the patient is incompetent and either terminally ill or
permanently unconscious. A durable power of attorney is a
document ... Tillyard notes. The reasons for this may be
multifactorial, ranging from the demands of managed care in
which the doctor–patient relationship has been undercut by
the consumer-driv...
Báo cáo y học: "Recently published papers: Heavyweight problems in the intensive care unit" potx
... and obesity. There
was, however, an increase in morbidity with a trend towards
longer length of stay, both in the ICU and in the hospital,
between the normal weight groups and the very obese
patients. ... views [2,3].
In the study by Sakr and colleagues, the European obser-
vational Sepsis Occurrence in Acutely Ill Patients study
database was interrogated to examine the effect o...
Báo cáo y học: " Cardiac effects of induction agents in the septic rat heart" potx
... Addi-
tionally, the slow down of the heart rate by midazolam might
reduce myocardial energy demands, and may additionally
improve diastolic filling of the heart.
We recognise the limitations of this study. ... critically ill patients [28]. However, the diagnosis of hypoten-
sion is easy, whereas the diagnosis of septic cardiomyopathy
is more sophisticated and requires a more compl...
Báo cáo y học: "Effects of first aid training in the kindergartena pilot study" pot
... topic as everyday life activity. The qualitative
descriptions of everyday situations showed the children’s
natural p roficiency for empathy. It has been stated that
empathy is one of the most important ... in the
kindergarten. They were take n during the course and the
following seven months after the course to investigate
the effects of first aid training on the children’s...
Báo cáo y học: "Virus-host interactions: new insights from the small RNA world" pot
... antigen increased the recognition of SV40-
infected cells by antigen-specific cytotoxic T cells [16] . The
viral miRNA may thus reduce the susceptibility of the virus
to the host immune system.
Viral ... recently been shown to sup-
press RNA-silencing pathways. The protein HC-Pro, encoded
by the tobacco etch potyvirus, was the first viral protein iden-
tified as suppressing RN...
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