Báo cáo y học: "Benchmarking ortholog identification methods using functional genomics data" doc

... many-to-many orthology relationships. How- ever, by including only one pair of orthologous sequences per orthologous group, that high score is balanced by a reduction in the total number of orthologous ... comparative genomics. Various methods are used to analyze cross-species orthologous relationships according to an operational definition of orthology. Often the definition of orthology i...

Ngày tải lên: 14/08/2014, 16:21

... mainly cytostati- cally compared with classical cytotoxic drugs require special timing of scans [68]. International guidelines for PET tests are therefore necessary to guarantee the quality and ... and P-glycoprotein [69, 70]. Thus nuclear medicine methods, usable under in-vivo conditions, are likely to play a key role in future clinical cancer treatment. Table 2. Tumor types for ....

Ngày tải lên: 25/10/2012, 11:10

... experimentally using both the enzyme inhibition assay as w ell as the cell growth inhibition assay. It is indeed gratifying that two of t he six compounds clearly exhibit enzyme inhibition. This clearly ... PRISM 7900 (Applied Biosystems) sequence detection system with the cDNA as template using PBEF1 specific primer set and a Dynam o kit con- taining SYBR green dye (Finnzymes). All measu...

Ngày tải lên: 10/08/2014, 09:22

... respiratory system. In Handbook of Physiology. The Respiratory System Volume III. Issue 1 Edited by: Macklem PT, Mead J. Bethesda: American Physio- logical Society; 1986:145-178. 12. Hoymann HG: ... measurement of murine respira- tory function has virtually become synonymous with the widely used barometric whole-body plethysmography method [35], some other noninvasive methods have been des...

Ngày tải lên: 12/08/2014, 15:21

... thermostat may be influenced by inflam- mation, or be deregulated by primary neurological damage. In hypothermia the body's re-warming mechanisms are less effective, especially when the body temperature ... this study we compared the efficacy of several commercially available cooling devices for temperature management in ICU patients with various types of neurological injury. Methods F...

Ngày tải lên: 13/08/2014, 08:20

... Faculty of Veterinary Medicine, University Utrecht, Yalelaan 104, 3584 CM Utrecht, the Netherlands, 2 Department of Pathobiology, Faculty of Veterinary Medicine, University Utrecht, Yalelaan ... NaCl biopsy followed by RNAlater preservation and an RNAeasy mini kit extraction yields optimal RNA quality from canine liver biopsies. The size of the biopsy needle used in this study was based on...

Ngày tải lên: 13/08/2014, 13:20

... 11:5-6. 17. Yang WL, Yu SP, Yang SL, Ren YD, Li YF: Determination of neo- heperidin in Fructus Aurantii by RP-HPLC. Shizhen Guoyi Guoyao 2005, 16:280-281. 18. Liang YY, Feng B, Zhu CC, Ni C: Determination ... flavonoid glycosides. Phytochem- istry 2000, 54:237-256. 23. Zhou D, Xu Q, Xue X, Zhang F, Liang X: Identification of O-dig- lycosyl flavanones in Fructus aurantii by liquid chromatogr...

Ngày tải lên: 13/08/2014, 15:21

... of 15 hydroxy-7,8,2',5'-tetramethoxyflavone, 5-hydroxy- 7,8,2',3'-tetramethoxyflavone, 5-hydroxy-7,8,2'- trimethoxyflavone, 7-O-methylwogonin and 2'-methyl ether ... anti-inflammatory properties [17], namely andrographolide, 14-deoxy-11,12-didehydroandrogra- pholide, ergosterol peroxide, 14-deoxy-14,15-dehydroan- drographolide, 5-hydroxy-7,8-dimethoxyflavone, 19-...

Ngày tải lên: 13/08/2014, 15:21

... (9) years Gender 15 male Weight 82 (19) kg Parsonnet score 10 (8) Duration of cardiopulmonary bypass 74 (17) minutes Coronary artery bypass graft 13 Aortic valve replacement 2 Coronary artery bypass ... water volume. EVLW volume may then be calculated by subtraction. ICG-thermal measure- ments were made by using the COLD-Z system (Pulsion Med- ical Systems, Munich, Germany) after central in...

Ngày tải lên: 13/08/2014, 16:21

... module. Using Bib- lioSphere PathwayEdition of Genomatix, the functional co- citations of p53-NFYC (nuclear factor YC) and p53-YB-1 (Y- box-binding protein 1) were observed, and NFYC and YB-1 belong ... that YB-1 (also known as DNA binding protein B) accumulates in the nucleus under genotoxic stress only when cells retain wild-type p53, whereupon YB-1 inhibits p53 activity [83]. The NFY...

Ngày tải lên: 14/08/2014, 07:21