Báo cáo y học: "Genes regulated by estrogen in breast tumor cells in vitro are similarly regulated in vivo in tumor xenografts and human breast tumors" doc
Báo cáo y học: "Genes regulated by estrogen in breast tumor cells in vitro are similarly regulated in vivo in tumor xenografts and human breast tumors" doc
... R28ResearchGenes regulated by estrogen in breast tumor cells in vitro are similarly regulated in vivo in tumor xenografts and human breast tumorsChad J Creighton*, Kevin E Cordero†, Jose ... 3E-14).Genes regulated by estrogen in breast cancer cell lines in vitro are also estrogen -regulated in xenograft tumors in vivo We sought to determine whether the genes showing regula-tion by estrogen ... number of genes induced by estrogen in vitro are correlated with PR mRNA expression in ERα+ human breast tumors in vivo An additional indicator of estrogen signaling activity in breast tumors is...
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Báo cáo Y học: Agmatine oxidation by copper amine oxidase Biosynthesis and biochemical characterization of N-amidino-2-hydroxypyrrolidine pdf
... ofL-arginine toL-citrulline (at pH 7.5 and 37.0 °C) and of the trypsin catalyzed hydrolysis ofN-a-benzoyl-L-arginine p-nitroanilide (at pH 6.8 and 21.0 °C) by N-amidino-2-hydroxypyrrolidine ... Values of Kifor N-amidino-2-hydroxypyrrolidine, agmatine, and clonidine binding to NOS-I, NOS-II, and trypsin.EnzymeKi(M)N-Amidino-2-hydroxypyrrolidine Agmatine ClonidineNOS-I (1.1 ± 0.1) ... N-Amidino-2-hydroxypyrrolidine binding mode tohuman NOS-II(top) and bovine trypsin (bottom). The conformations of N-amidino-2-hydroxypyrrolidine in the enzyme:inhibitor complexes were ob tainedafter...
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Báo cáo Y học: Calcium-binding by p26olf, an S100-like protein in the frog olfactory epithelium pot
... Ca21-binding to p26olf is EF-B, EF-A, EF-C and EF-D. In these EF-hands, EF-B and -D are the p26olf-specificEF-hands and probably show high affinity for Ca21-binding,while EF-A and EF-C are S100-specific ... helix contentwas attained by binding of two Ca21. Interestingly, in themutants which have only three Ca21-binding sites, thebinding of two Ca21was sufficient to induce more than 70%of ... Ca21-binding to each EF-hand (named EF-A,-B, -C and -D from the N-terminus of p26olf), we examinedCa21-binding in wild-type p26olf and also in its mutants in which a glutamate at the –z coordinate...
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Báo cáo Y học: Conformational analysis by CD and NMR spectroscopy of a peptide encompassing the amphipathic domain of YopD from Yersinia potx
... [10]. In addition, we and others observedthat a yopD null mutant is constitutively induced forsynthesis of Yops in vitro, while Yop synthesis in wild typebacteria remained tightly regulated in ... according to classicalprocedures including spin system identification and sequen-tial assignment [42]. Initial spin system assignments ofYopD278)300were obtained using COSY and TOCSYspectra and ... encodesnumerous Yop (Yersinia outer protein) and Lcr (lowcalcium response) virulence determinants that are secreted by the Ysc (Yersinia secretion) type III apparatus [3,4]. Twoprotein classes are secreted...
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Báo cáo y học: "Factor XII mutations, estrogen-dependent inherited angioedema, and related conditions" doc
... ofbradykinin.Androgens: effect on bradykinin productionC-1 INHAndrogens increase the level of C-1 INH [39,40], which in turn inhibits activated factor XII and kallikrein, redu-cing bradykinin ... and therapy. J Allergy Clin Immunol 2009, 124:129-34.17. Duan QL, Binkley K, Rouleau GA: Genetic analysis of factor XII and bradykinin catabolic enzymes in a family with estrogen- dependentinherited ... C:Increased englobulin fibrinolytic potential in womenon oral contraceptives low in oestrogen levels of extrinsic and intrinsicplasminogen activators, prekallikrein, factor XII and C1 inactivator.Thromb...
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Báo cáo y học: "Specific immunotherapy by the sublingual route for respiratory allergy" pot
... asked by phone (without beingwarned in advance) to count the remaining tablets in the box; the phone interview was done during the firstyear in patients treated for dust mite allergy and duringthe ... as: Incorvaia et al.: Specific immunotherapy by thesublingual route for respiratory allergy. Allergy, Asthma & ClinicalImmunology 2010 6:29.Incorvaia et al. Allergy, Asthma & Clinical ... evaluation of sublingualimmunotherapy vs symptomatic treatment in adults with pollen-induced respiratory allergy: The Sublingual Immunotherapy PollenAllergy Italy (SPAI) study. Ann Allergy Asthma Immunol...
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Báo cáo y học: "Cartilage preservation by inhibition of Janus kinase 3 in two rodent models of rheumatoid arthritis" doc
... of Januskinase 3 (JAK3), a critical enzyme in the signaling pathway ofmultiple cytokines (interleukin (IL)-2, -7, -15 and -21) that are important in various T cell functions including development,activation ... calcineurin inhibition, yethas demonstrated efficacy in a number of animal modelsincluding delayed-type hypersensitivity and cardiac allograftrejection [5,6]. CP-690550 is a small molecule inhibitor ... buffered formalin. Limbs and pawswere routinely processed, embedded in paraffin, sectioned and analyzed as previously described [14].IL-6 analysisSerum IL-6 levels were measured by enzyme-linked immuno-sorbent...
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Báo cáo y học: "Osteoarthritis associated with estrogen deficiency" docx
... pathway by estrogens via TGF-β mRNA induction; increase of estrogen and TGF-β/SMAD signaling due to cytoplasmic MAP kinaseactivity; direct interaction between ERs and the SMAD proteins in the cytoplasm ... non-genomicpathways described in human articular and rat growth platechondrocytes. Thus, only female cells respond to estrogens by promoting a rapid protein kinase C (PKC)-α-mediatedincrease in proteoglycan ... joint tissues Estrogen influences the biology of joint tissues by regulatingthe activity and expression of key signaling molecules in several distinct pathways (Figure 3).Canonical estrogen receptor...
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Báo cáo y học: "Further benefits by early start of HIV treatment in low income countries: Survival estimates of early versus deferred antiretroviral therapy" potx
... Abo Y, Salamon R, Bissagnene E, Seyler C, Eholié S, Anglaret X: Incidence and determinants of mortality and morbidity following early antiretroviraltherapy initiation in HIV-infected adults in ... and onwards to inform differently.One-way sensitivity analyses (table 3) identified effectsof applying low and high mortality rates and ages in theMarkov model. High and low mortality rates in the ... 200-3500.02.04.06.08.010.012.014.016.018.020.00.72.04.87.27.614.5Remaining life years no treatmentLife years gained from HAARTFigure 2 Mean remaining life years without treatment and lifeyears gained from HAART stratified in three baseline CD4ranges.Johansson...
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Báo cáo y học: "Drug efficacy by direct and adjusted indirect comparison to placebo: An illustration by Mycobacterium avium complex prophylaxis in HIV" potx
... al.study to baseline characteristics in Nightingale et al.,using the rifabutin arms in each study, we estimated theefficacy of clarithromycin in Benson et al. compared toplacebo in Nightingale ... other.Efficacy by direct comparisonWe used data from three studies, by Nightingale et al.,Pierce et al., and Oldfield et al.tocomparerifabutin,clarithromycin, and azithromycin to placebo, directly(Table ... monthly failure probabilities of:aCompared to azithromycin in Oldfield 1998 [15].bCompared to clarithromycin in Pierce 1996 [14]cCompared to rifabutin in Nightingale 1993 [13]dCompared...
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Từ khóa: Báo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018Nghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Sở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXChuong 2 nhận dạng rui roTranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)BÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀM