Báo cáo y học: "Multi-genome biology" ppsx

... spectrometry to identify the individual phosphoryla- tion sites. A second strategy, described by Philippe Bastiaens (EMBL, Heidelberg, Germany) is to express a library of fluo- rescently tagged ... biologists to move beyond the constraints of studying only a few rather arbitrarily chosen model organ- isms and out into the diversity of pathologically, agricultur- ally, or evolutionarily intere...

Ngày tải lên: 14/08/2014, 14:21

... targeted search for sequence copy-number polymorphisms (CNPs) in segmental duplications using array comparative genomic hybridization (array-CGH) was reported by Andrew Sharp (University of Washington, Seattle, ... relatively gene-rich. Certain Gene Ontology terms related to environmental responses (that is, extra- cellular proteins, olfactory receptors, and acquired and innate immunity) were...

Ngày tải lên: 14/08/2014, 14:22

... [http://meetings.cshl. edu/meetings/abstracts/2006systems_absstat.html]. Studying genome occupancy and protein-DNA interactions Chromatin immunoprecipitation followed either by DNA hybridization to microarrays (ChIP-chip) or by DNA sequencing ... presentations largely focused on identification and analysis of protein- DNA interactions, the discovery of cis-regulatory motifs, and the applicat...

Ngày tải lên: 14/08/2014, 16:21

... B, Gou JY, Wang LJ, Chen XY: Control of plant trichome development by a cotton fiber MYB gene. Plant Cell 2004, 16:2323-2334. 10. Machado A, Wu Y, Yang Y, Llewellyn DJ, Dennis ES: The MYB tran- scription ... development. Conclusions Analyses of massively parallel sequencing data, miRNA microarrays, small RNA blots, and target cleavage assays indicate that rapid and dynamic changes in gene e...

Ngày tải lên: 09/08/2014, 20:20

... main methods currently used by clinicians to classify the severity of COPDFigure 1 The main methods currently used by clinicians to classify the severity of COPD. Respiratory Research 2009, 10:29 ... resonance. Ultramicroscopy 2008, 108(10):1379-1383. 148. Zhang Y, Luo S, Tang Y, Yu L, Hou KY, Cheng JP, Zeng X, Wang PG: Carbohydrate-protein interactions by "clicked" carbohy- drate...

Ngày tải lên: 12/08/2014, 14:20

... by functionally active TFs, interacting networks and signaling pathways. This study is the first utilization of COGRIM to analyze a fam- ily of TFs in a human cancer system [47,53]. Previously, ... cells by differential display and http://genomebiology.com/2008/9/3/R53 Genome Biology 2008, Volume 9, Issue 3, Article R53 Yan et al. R53.13 Genome Biology 2008, 9:R53 We experimentally validated...

Ngày tải lên: 14/08/2014, 08:20

... underlying mechanisms of this phenomenon in the Ashbya gossypii, a filamentous fungi related to yeast, and revealed a number of surprises. Notably, the levels of cyclins and other cell-cycle regulators ... the cell cycle in Ashbya as is common in other eukaryotes, including the uninucleate model yeasts S. cerevisiae and Schizosaccharomyces pombe. She suggested that the cell cycle in Ashbya mi...

Ngày tải lên: 14/08/2014, 14:21

... path- ways. In these systems, therefore, inactivating enzymes in MAP kinase cascades have a key role not only in suppressing the level of pathway activity in unstimulated cells and during recovery ... culture, as assayed by acquisi- tion of a cell-type-specific enzymatic activity and mineraliza- tion, and in vivo, as assayed by bone formation following implantation in mice [3]. The ability to...

Ngày tải lên: 14/08/2014, 14:22

... ‘tra- ditional’ way) gives you the same result, especially for such a straightforward phylogenetic question? I think the answer is in large part that the construction of this phylogeny was not the only object ... exclusively based on cloning has been used again. This time two metagenomic libraries were constructed by anonymously cloning all DNA present in the samples. One library was from a 4...

Ngày tải lên: 14/08/2014, 15:20

... http://genomebiology.com/2006/7/8/113 © 2006 BioMed Central Ltd Almost thirty years ago, I was sitting in my basement office (they always used to put X-ray crystallography labs in the basement in those days ... without my realizing it, I have become what I beheld. I'm suddenly past my prime, an object of pity or derision for my younger col- leagues, old scientifically as well as physica...

Ngày tải lên: 14/08/2014, 17:22