Báo cáo y học: "Loss of LIN-35, the Caenorhabditis elegans o

Báo cáo y học: "Loss of LIN-35, the Caenorhabditis elegans ortholog of the tumor suppressor p105Rb, results in enhanced RNA interference" pps

... neuronally expressed genes are largely refractive to RNAi in wild-type worms. Results: We found that C. elegans strains carrying mutations in lin-35, the worm ortholog of the tumor suppressor gene p105Rb, ... in the LIN-35/ p105Rb chromatin-remodelling pathway also result in RNAi hypersensitivity in C. elegans. Indeed, we found that a strain- carrying a null al...

Ngày tải lên : 14/08/2014, 16:20

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Báo cáo y học: "Blood autoantibody and cytokine profiles predict response to anti-tumor necrosis factor therapy in rheumatoid arthriti" pps

... the representative cluster shown in Figure 3. Cytokine profiling using a bead-array system We performed multiplex cytokine profiling using the Luminex bead array system and methods previously ... bead-array cytokine assay for integrated analysis of cytokine and autoantibody profiles in baseline samples derived from all three cohorts of etanercept new-start RA patients. Combined...

Ngày tải lên : 09/08/2014, 14:21

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Báo cáo y học: "Levamizole enhances immune responsiveness to intra-dermal and intra-muscular hepatitis B vaccination in chronic hemodialysis patients" pps

... maintaining hepatitis B immunity in hemodialysis patients. vaccine 2002, 20:3230-35. 21. Pyone kyi K, May Oo K, Moh Htun M, Win Maw T, Khin Khin A, San San O, et al.: Clinical trial of the intradermal ... the antibody titer is maintained. Kayatas [26] in another study reported the effect of Levamisole on the percentage of patients who found HB Antibody seroconversion but the...

Ngày tải lên : 11/08/2014, 10:23

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Báo cáo y học: "Current antibody-based immunoassay algorithm failed to confirm three late-stage AIDS cases in China: case report" pps

... review b y the Editor -in- Chief of this journal. Additional file 1: Results of variable testing for the three cases during the following-up period. The data provided represent the results of variable ... opportunistic infection in all three patients though they were persistently indeterminate on the Wes- tern blot assays. The discordant clinical and serological r...

Ngày tải lên : 12/08/2014, 04:20

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Báo cáo y học: " CD4+CD25+ T regulatory cells from FIV+ cats induce a unique anergic profile in CD8+ lymphocyte targets" pps

... complex role in cell c ycle regulation by facilitating the activity of the D cyclin family, while inhibiting the activity of cyclin E [28,49]. As shown in Figure 4 and Figure 6, in CD8 + target ... suppression, we asked whether Treg cells induce anergy through the alteration of production of cyclins, cyclin-dependent kinases and their inhibitors. Results: Lymphocytes we...

Ngày tải lên : 13/08/2014, 01:20

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Báo cáo y học: " Programmed death-1 levels correlate with increased mortality, nosocomial infection and immune dysfunctions in septic shock patients" ppsx

... characterized by an increased production of anti-inflammatory cytokines (mainly interleukin-10 (IL-10) and transforming growth factor-beta) [7], increased lymphocyte apoptosis [8], increased proportion of ... reduced cytokine synthesis (interferon-gamma (IFN-g)orIL-2orboth [21-24]). The co-inhibitory PD-1 system has been stu- died mainly in viral diseases and oncology. This system may...

Ngày tải lên : 14/08/2014, 08:21

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Báo cáo Y học: Loss-of-function variants of the human melanocortin-1 receptor gene in melanoma cells deﬁne structural determinants of receptor function doc

... shift of the displacement curve and by the lower amount of radioactivity bound in the absence of competitor (in spite of the lack of statistically signiﬁcant differences in the number of binding ... lines, and that impairment of signaling through the cAMP cascade occurs in these cells even in the absence of mutations in the coding region of the g...

Ngày tải lên : 17/03/2014, 10:20

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Báo cáo y học: "Does switching from oral extended-release methylphenidate to the methylphenidate transdermal system affect health-related quality-of-life and medication satisfaction for children with attention-deficit/hyperactivity disorder&

... by the AIM-C, was also generally improved over the course of the study. At baseline, most caregivers indicated inconsistency in their child's behavior across the day in contrast to endpoint ... social interactions since beginning the study medication, and 91.9% were satisfied with the efficacy of the study medication on their child's attention. The majority...

Ngày tải lên : 25/10/2012, 10:06

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Báo cáo y học: "Why are some children with early onset of asthma getting better over the years" -aneuploid-prostate-cancer-cells-after-tmz-tmz-bioshuttle-treatment.html#post143974

... University Hospital, including PHC data of the statements made by the mid-wife in her records of the check-up of the mothers during the pregnancy (17). In the follow-up at the age of seven, ... suffering neonatal death and those living outside the region, were included in the study. At the age of seven, all of them still living in the region wer...

Ngày tải lên : 26/10/2012, 09:48

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Báo cáo y học: "Grb2-associated binder 1 polymorphism was associated with the risk of Helicobactor pylori infection and gastric atrophy"

... that bind to the SH2 domains. The tandem SH2 domains bind to Tyr-627 and Tyr-659 simultaneously in a specific orientation, in which Tyr-627 binds to the N-SH2 domain and Tyr-659 binds to the ... biologically plausible observation would stimulate interest in the study of the molecular mechanisms of action of this polymorphism. Because these results were based on...

Ngày tải lên : 31/10/2012, 15:37

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