Báo cáo y học: "Bioinformatics meets systems biology" pps

... Germany) and Thomas Höfer (Hum- boldt University, Berlin, Germany). Vinkemeier described a thorough experimental analysis of the STAT1 signaling system, focusing on the nucleocytoplasmic cycling ... stressed by Martin Vingron (Max Planck Institute for Molecular Genetics, Berlin, Germany). He compared microarray experiments on the cell cycles of three model eukaryotes, namely budding yeast, fi...

Ngày tải lên: 14/08/2014, 16:20

... C, Lehrach H: Systems Biology in Practice Berlin: Wiley-VCH; 2005. 449 pages, ISBN- 10 3-527-31078-9, ISBN-13 978-3-527-31078-4. Eur 99.00 hardback Systems biology – the study of such functional ... book surveying the concepts, methods and potential applica- tions of this nascent though already wide field was a chal- lenging enterprise, but the authors of Systems Biology in Practice h...

Ngày tải lên: 13/08/2014, 23:20

... MMTV PyMT '89 FVB/N MMTV PyMT '91#3 FVB/N MMTV PyMT '91#2 FVB/N MMTV PyMT '31 FVB/N MMTV PyMT 575 FVB/N WapMyc CA02-569A FVB/N WapMyc CA02-545A FVB/N WapMyc CA02-567C ... CA02-567C FVB/N WapMyc CA05-867A FVB/N WapMyc CA02-548A FVB/N WapMyc CA02-579C FVB/N WapMyc CA02-549A FVB/N WapMyc CA02-579F FVB/N WapMyc CA02-540A FVB/N WapMyc CA02-544A FVB/N WapMyc...

Ngày tải lên: 14/08/2014, 07:21

... llooggyy Nature 2005, 440022((SSuuppppll)):: C47-C52. Kirschner M: TThhee mmeeaanniinngg ooff ssyysstteemmss bbiioollooggyy Cell 2005, 112211:: 503-504. Kitano H: SSyysstteemmss bbiioollooggyy:: ... in that system. IInn hhiigghh sscchhooooll II hhaatteedd pphhyyssiiccss aanndd mmaatthh,, bbuutt II lloovveedd bbiioollooggyy SShhoouulldd II ggoo iinnttoo ssyysstteemmss bbiioollooggyy?? N...

Ngày tải lên: 06/08/2014, 18:21

... pathways, but also revealed the cooption of cell-cycle circuits in the antiviral response. is approach to systems biology could also be applied to numerous other cell-based models. Underlying ... more generally, gene regulation. Unconventional interactions of the secondary type e late Ed Lewis famously said ‘Progress will still need to be driven by the logic of genetics and by furth...

Ngày tải lên: 09/08/2014, 20:21

... oxide synthase 3 (endothelial nitric oxide synthase); HMG-CoA: 3-hydroxy-3-methylglutryl coenzyme A; ERα: estrogen receptor alpha; PI3K: phosphatidylinositol 3-kinases; PIP2: phophatidylinositol ... an already existing vessel into two by formation of transcapil- lary pillars followed by vascular myogenesis, although the exact mechanism is poorly understood [7]. Angiogenesis is necessary durin...

Ngày tải lên: 10/08/2014, 21:23

... differ- ently than predicted by those studying cellular mRNAs. Many of the important discoveries in RNA biology were made by study of viral RNA. The only disadvantage is you have to go to twice as many ... Also, you have to get used to having your session at the Retroviruses meeting on Sunday morning. KBL: What is currently the most exciting research in your laboratory? KB: I am tremendously...

Ngày tải lên: 13/08/2014, 05:22

... errors of omission and commission may be replaced by new errors facilitated by the technology itself [7]. It is with this fairly limited background that the paper by Morrison and colleagues [1] provides ... a before-and-after study of the implementation of a fully inte- grated electronic patient record into their 25-bed ICU, they observed and video-recorded team interactions during daily roun...

Ngày tải lên: 13/08/2014, 11:23

... simply. Author details 1 Department of Biology, Rutgers The State University of New Jersey, 315 Penn St., Camden, NJ 08102, USA. 2 Department of Physics, Rutgers The State University of New Jersey, ... lamented the view of many cell biologists that “molecular analysis of cellular functions” is the only acceptable approach to cell biology [13], yet this precarious ideology seems even more entr...

Ngày tải lên: 13/08/2014, 16:20

... scoring systems developed or validated in the MAU. We hypothesized that the existing scoring systems would have a low level of evidence and that only few systems existed that had been externally validated. Materials ... to design and test the systems, what was the discri- minatory power and calibration of the systems (i.e. how usable are the systems) and which level of evidence does...

Ngày tải lên: 13/08/2014, 23:21