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Báo cáo y học: "A novel approach to identifying regulatory motifs in distantly related genomes" pps

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Báo cáo y học: "A novel approach to identifying regulatory motifs in distantly related genomes" pps

... Article R113MethodA novel approach to identifying regulatory motifs in distantly related genomesRuth Van Hellemont*, Pieter Monsieurs*, Gert Thijs*, Bart De Moor*, Yves Van de Peer† ... successful in the identification of regulatory motifs, phylogenetic footprintingmethods still show some shortcomings. To assess these difficulties, most apparent when applyingphylogenetic footprinting ... more distantly related species can greatly improve the detection of conserved regulatory motifs. By adding more distantly related sequences, the conserved functional motifs can be more easilydistinguished...
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Báo cáo y học: "A novel approach to measure the contribution of matrix metalloproteinase in the overall net proteolytic activity present in synovial fluids of patients with arthritis" pptx

... other factors mayexplain the failure of MMP inhibitors in clinical trials. Forinstance, some members of the MMP family were recentlyshown to exert an anti-inflammatory activity in some physiolog-ical ... stimulated by inflammatorycytokines [21,22]. To assess whether inflammation does cor-relate with the proteolytic activity in arthritic joints, we firstcompared the NPA with the number of infiltrating ... proteolytic activity. This suggests that, in thecase of arthritis with involvement of several joints, systemicfactors play a dominant role in controlling the local proteolyticactivity. Finally,...
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Báo cáo y học: "A novel approach to sonographic examination in a patient with a calf muscle tear: a case report" docx

... latercomplaining that the pain in his left calf area persistedand could be further aggravated by tiptoeing and weightbearing maneuvers. Again, US examination in the proneposition did n ot reveal any ... sonographic findings. However, he still complained of persistent pain in his left calf area. Adifferent ultrasound examination approach was then performed with the patient lying in the supineposition ... muscle painduring rigorous steep mountain climbing. ConventionalUS examination in the prone position revealed normalsonographic findings. It was not until the third USexamination in which...
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Báo cáo y học: "A novel approach to modelling water transport and drug diffusion through the stratum corneum" pdf

... tensor:KKKKKKKKKKxxzzxy xzyx yy yzzx zy=⎡⎣⎢⎢⎢⎤⎦⎥⎥⎥.Considering the mass flux of fluid into an REV, and by further d efining R* Δx y z to be the volumetric inflow rate (with R* > 0 referring to ... soaking in excess water. However , swelli ng doesnot hint to any permeability property, but simply means that corneocytes contain pro-teins that can bind water molecules. Moreover, corneocytes ... within an intercellular channel , followed by a corneocyte, followed by a secondintercellular channel. Correspondingly, location #2 refers to points within a corneocyte,followed by an intercellular...
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Báo cáo y học: "A novel scheme to assess factors involved in the reproducibility of DNA-microarray data" pdf

... used to obtain DNA-microarray data of improved quality. A novel scheme to assess factors involved in the reproducibility of DNA-microarray data Running title: a novel scheme to assess ... due to hybridization and sampling. Some factors are confounded Due to the fact that in our DNA-microarray laboratory validation experiments are only performed when necessary (i.e. to introduce ... due to day -to- day differences, identity of the experimenter, and DNA microarray batch differences. e Due to overlap in levels, the contribution of these interactions were individually determined....
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Báo cáo y học: " A Practical Approach to Managing Patients with HCV Infection"

... Symptoms in HCV infection do not appear to be linked to disease activity; neither do appear to be correlated with serum aminotransferase levels or liver histological findings [15,16]. In ... A phase II study indicated a lower rate of anemia induced by viramidine than ribavirin. However, its efficacy remains to be determined by ongoing clinical trials. Several types of HCV-specific ... Natural History of HCV Infection The natural history of HV infection was thoroughly reviewed by Drs. Chen and Morgan in this issue. Knowing the natural history of HCV infection is important in the...
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Báo cáo y học: "A Practical Approach to Management of Chronic Hepatitis B"

... hepatic inflammation carry a significantly higher risk of disease progression. Histological staging of HBV disease is clinically very valuable in assessing degree of fibrosis and predicting disease ... liver biopsy may not be necessary. As it will be discussed below, histological assessment is very valuable in determining HBV treatment in patients with persistently normal transaminases. ALT ... challenge remains in optimizing HBV therapy. First, further understanding HBV dynamics and correlation of the level of HBV replication with liver injury will be invaluable for us to define an evidence-based...
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Báo cáo khoa học: "A Novel Approach to Semantic Indexing Based on Concept" ppt

... basic indexingmethods by presenting a novel approach using a con-cept vector space model for extracting and weightingindexes. Our experiment for semantic indexing sup-ports the validity of ... index term extractionbased on the concept vector space, which will be ex-plained in the next section.3.2 Lexical Chains and Concept Vector SpaceModelLexical chains are employed to link related ... participated in this study. The textswere composed of average 11 lines in length(aboutfive to seventeen lines long), each focused on aspecific topic relevant to exercise, diet, holidayblues,yoga,...
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Báo cáo y học: "A new approach to understanding the impact of circadian disruption on human health'''' pps

... behavior can only yield partial insightinto circadian entrainment. It is presently impossible to directly measure SCN activity in vivo, and thus it is impos-sible to measure entrainment in the purest ... theyreturned the device for data analyses. In addition to wear-ing the Daysimeter, participating nurses provided urinesamples, obtained every four hours, for subsequent mela-tonin assay and ... for systematically studying the impactof light-induced circadian disruption in humans and in animal models. Ecological light and activitydata are needed to develop the essential insights into...
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Báo cáo y học: "A novel method to identify and characterise peptide mimotopes of heat shock protein 70-associated antigens" pptx

... mixture of baits.For example, intravenously administered phage displaylibrary has been successfully used for in vivo bio-panning in certain animal model systems to identify tissue-specificpeptide ... synthetic biotinylated TMGpeptide (Fig. 1C, TMG). Conversely, phages displaying theTMG peptide bind to a synthetic biotinylated DSP peptide(Fig. 1C, DSP). In the absence of biotinylated peptides, ... Bond*†1Address: 1Moyne Institute for Preventive Medicine, Department of Microbiology, University of Dublin, Trinity College, Dublin 2, Ireland, 2Institute of Immunology & Department of Biology, National...
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