Báo cáo y học: "Systematic analysis of gene expression in human brains before and after death" docx

... may alter gene expression patterns in postmortem human brains. Study of expression levels of 14 genes in human brain autopsy and biopsy samplesfound significant change in one of the genes, indicating ... protein ubiquitination issignificantly increased after death, while the expression of genes involved in protein biosynthesis, rRNA processing,organelle organization and biogenesis and induction ... work is properly cited.Profiling post-mortem human brains& lt;p>Comparison of the gene expression profiles of pre- and post-mortem human brains suggests that post-mortem human brain samples are...

Báo cáo y học: "Microarray analysis of gene expression in lupus" ppt

... patients and 12 controls [18].The microarray assay used (Panorama Cytokine Gene Array membranes; Sigma Genosys, Inc) included375 genes enriched in cytokines, chemokines, cell surface286ably derive ... together and were preferentially inducedby a combination of IFN-α and IFN-β. However, two genespreferentially induced by IFN-γ (SERPING1 and FCGR1A) were also significantly increased in the SLEpatients ... amongthe IFN-induced genes overexpressed in the JDM musclesamples. Increased expression of several genes, includingG1P3 (encoding IFN-induced 6-16) and CDKN1A (p21cyclin kinase inhibitor),...

Báo cáo y học: "Social regulation of gene expression in human leukocytes" pps

... microarray analysis identified 209 genes that were differentially expressed in circulating leukocytes from 14 high- versus low-lonely individuals, including up-regulation of genesinvolved in immune ... activation and prolif-eration. Several other indications of immune activationemerged in the set of over-expressed genes, including pro-inflammatory cytokines, chemokines, granzymes, protein-ases, and ... theme of a highly activated, proliferative phenotype in circulating leu-kocytes from socially isolated individuals by identifying over-representation of Gene Ontology (GO) annotations involvingimmune...

Báo cáo y học: "Systematic analysis of transcribed loci in ENCODE regions using RACE sequencing reveals extensive transcription in the human genome" pptx

... studies of the entire human genome are thus likely to expand the number of protein cod-ing genes accordingly.Complementary natural antisense transcripts exert control atmany steps of gene expression ... standard hybridization, staining, and wash-ing protocols. The arrays were scanned on an Affymetrix 7GPlus GeneChip scanner, and the signal intensity data wereprocessed using a sliding window ... novel and known RNA transcripts from known genes that were not pre-viously detected in NB4 cells using genomic tiling arrays. It isthus likely that many (and possibly the majority) of knowngenes...

Báo cáo y học: "Mouse maps of gene expression in the brain" pot

... farthest in describing the anatomy of gene expression and compares data from numbers of individualanimals using different methods to assay gene expression. However, the number of genes covered remains ... function and development of circuits in the brain and for geneticmanipulation of circuit elements. This level of analysis willbe critical to the next stages of understanding how changes in gene ... categorize pyramidal neurons in layer 5 of the neocortex in mice, demonstrating that theanatomical distinctions also have gene- expression corre-lates. Sugino et al. [22] combined microarray analysis...

Báo cáo y học: "Microarray analysis of microRNA expression in the developing mammalian brain" ppt

... closely related family members isan artifact of hybridization.Profile of microRNA expression in the developing mouse brainFigure 3Profile of microRNA expression in the developing mouse brain. ... Quantification of microarray data using three synthetic RNAs: syn1, syn2 and syn3. Each data point is the average of two independent labelling/hybridization reactions. Probes for the three synthetic ... mouse brain develop-ment [39]. Their study used a dot-blot array approach and direct labeling of microRNAs using radioactivity instead of aglass microarray and RT-PCR/fluorescent labeling, as...

Báo cáo y học: " Differential regulation of neurotrophin expression in human bronchial smooth muscle cells" pptx

... clarify the role and pathogenic importance of Th1/Th2 cytokines and neurotrophin release in asthmapathogenesis.Proliferation and survival of mast cells, eosinophils and lymphocytes in the airways ... neurotrophin mRNA and protein expression We next investigated the ability of the proinflammatorycytokine IL-1β to induce neurotrophin expression in HBSMC. At 2.5 h after addition of IL-1β (10 ... be elevated during airway inflammation and evoke airway hyperresponsiveness. Westudied if HBSMC may be a source of NGF, BDNF and NT-3, and if so, how inflammatory cytokinesmay influence their...

Báo cáo y học: "Systematic analysis of genome-wide fitness data in yeast reveals novel gene function and drug action" pot

... (Figure2c): rapamycin, calyculin A and wiskostatin. The similar-ity in these profiles resulted from inhibition of strainsdeleted for genes involved in intracellular transport and multidrug resistance ... com-prehensive view of drug-protein interactions. Suchresults can play an invaluable role in understanding and predicting a compound's clinical effects and in guiding itsuse, including predicting secondary, ... role in the exocyst.A second intriguing finding is our prediction of aninteraction between clozapine and both yeast Cox17 and its human homolog. Clozapine's primary targets areHillenmeyer...

Báo cáo y học: "Systematic overestimation of gene gain through false diagnosis of gene absenc" pps

... gain and loss both in terms of defining and of detecting them, and failure to recognize gene remnants will inevitably lead tomistaking a situation like that shown in Figure 1b (in which a gene ... pseudogenes and gene remnants (regions recognizableas gene- derived only by synteny and statistically significant sequence simi-larity to the parent gene) . There is thusan inherent asymmetry between ... theresult of loss of a gene X initially present in the ancestor would, in contrast,require a minimum of four separateevents, a seemingly less parsimoniousscenario. However, reasoning byparsimony in...

Báo cáo y học: "Proteome analysis of bronchoalveolar lavage in Pulmonary Langerhans cell histiocytosis" pptx

... ribosylation factor-like protein 3 and annexin A3 (ANXA3)), proteins involved in ion transport (such as serotransferrin (TRFE) and hemoglobin subunit beta) and several inflammatory proteins (including ... phosphorylase, pyruvate kinase isozymes, fibrinogen gamma chain, alpha 1B glycoprotein and actin cytoplasmic 1 were identified. BAL proteome analysis of PLCH patients also revealed several proteolytic ... against this pro-inflammatory cytokine. Interestingly in our PLCH patients this mechanism was down-regulated. The results of our proteome analysis of PLCH BAL suggested the involvement of some...

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Từ khóa: Báo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018 Nghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THz Giáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôit ĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN Phối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọ Phát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ long Nghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùng Nghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000 Định tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tin Thiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khí Chuong 2 nhận dạng rui ro Tổ chức và hoạt động của Phòng Tư pháp từ thực tiễn tỉnh Phú Thọ (Luận văn thạc sĩ)Tăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vật Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vật Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vật Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vật BÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘI Đổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt nam