Báo cáo y học: "The undertranslated transcriptome reveals widespread translational silencing by alternative 5'''''''' transcript leaders" doc

... R111 Research The undertranslated transcriptome reveals widespread translational silencing by alternative 5' transcript leaders G Lynn Law ¤ , Kellie S Bickel ¤ , Vivian L MacKay ¤ and David ... under-trans- lated by this analysis. Transcripts regulated at the level of polypeptide elongation may be prominent during early embryonic development [29,30] and among transc...

Ngày tải lên: 14/08/2014, 16:20

... approximately 60 days. In newborns, hind limbs, eyes and ears, immune system and reproductive tissues are particularly poorly developed (altricial), the gonads are still undifferentiated and endothermy ... wallaby Macropus eugenii). In particular, M. domestica and the tammar wallaby are roughly the same evolutionary distance from each other as humans are from mice. This makes these two pairs...

Ngày tải lên: 14/08/2014, 08:20

... suggest that children orphaned by AIDS may have unmet psychological needs. The finding of strikingly high PTSD-type symptoms in this study indicate that this should be a key area for research and intervention. ... instruments, to test hypotheses suggested by the liter- ature to date. Hypothesis We hypothesised that children who were orphaned by AIDS would show a higher incidence of psyc...

Ngày tải lên: 08/08/2014, 21:20

... study shows that monocyte-derived DCs are sen- sitive targets of LEF-M, possibly by inhibitory effects on NF-κB. DCs are affected by LEF-M at all major stages in their life cycle, ultimately leading ... impaires cytokine production and the allostimulatory capacity of monocyte-derived dendritic cells DCs are typically characterized by their ability to produce large amounts of predomina...

Ngày tải lên: 09/08/2014, 06:22

... the induction of IL-4 by phorbol 12-myristate 13-acetate and ionomycin or of IL-5 and IL-13 by phorbol 12-myristate 13- acetate and dibutyryl cAMP was partly abrogated by SB203580 [59,66]. In ... transcrip- tional activity by phosphorylation of NFAT and by activation of NFAT nuclear export [73,74]. An alternative transcription factor that is regulated by p38 MAPK is the Th2-spec...

Ngày tải lên: 09/08/2014, 07:20

... Medical Botany. John Wiley &Sons. N. York; 1977, 515. 32. Elujoba AA, Odeleye OM, Ogunyemi CM: Traditional medicine development for medical and dental primary health care delivery system in Africa. ... who participated in the study. Author details 1 Department of Community Dentistry, University of the Western Cape, Tygerberg, South Africa. 2 Department of Dentistry. Regional Hospital, Bam...

Ngày tải lên: 10/08/2014, 09:21

... an exercise that more selectively activates this muscle. * Correspondence: mbpohl@ucalgary.ca 1 Running Injury Clinic, Faculty of Kinesiology, University of Calgary, Calgary, AB, Canada Full list ... All subjects were currently free from lower extremity injury, had no prior history of surgery to the foot and lower leg, and were familiar with treadmill walking. The study was approved by th...

Ngày tải lên: 10/08/2014, 21:24

... parenchyma. Recently, techniques for detecting and quantifying elastin degradation in body flu- ids have advanced in specificity, sensitivity and accuracy by the use of mass spectrometry[3]. Desmosine ... emphy- sema" Pulmonary Emphysema: the Rational for Therapeutic Intervention. Ann NY Acad Sci 1991, 624S:7-12. 5. Ma S, Lin YY, Turino GM: Measurements of Desmosine and Iso- desmosine...

Ngày tải lên: 12/08/2014, 14:20

... markedly. The hyper- oxia-induced increases in G and H were significantly inhibited by TEZ administration. η was not affected by hyperoxia or TEZ. The ET-1-induced changes in the airway and tissue mechanical ... and it may therefore play a role in the regu- lation of the airway tone. Separate assessment of the air- way and tissue responses to ET-1 in mice previously has only been achieved...

Ngày tải lên: 12/08/2014, 16:20

... spermatogenesis even in early HIV infection. Infection of spermatogonia has only been previously reported by one study [28], though not via IF. Meiotic and Electron microscopy analysis of the epididymis of infected ... vesicles, urethra, testis, epididymis) may be targeted by the virus in the very early stage of infection [19]. While seminal plasma and seminal leukocytes originate mainly...

Ngày tải lên: 13/08/2014, 09:20