Báo cáo y học: "Using Topology of the Metabolic Network to Predict Viability of Mutant Strains" docx

Báo cáo y học: "Using Topology of the Metabolic Network to Predict Viability of Mutant Strains" docx

Báo cáo y học: "Using Topology of the Metabolic Network to Predict Viability of Mutant Strains" docx

... lethal, while others are tolerated. Here we untangle the topology and stoichiometry of the metabolic network and show that topology alone is sufficient to predict the viability of mutant strains ... mutants have either untouched primary synthetic pathways or only short re-routing (e.g. due to isozymes). Performance of other topology- based measures. We tested t...
Ngày tải lên : 14/08/2014, 16:20
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Báo cáo y học: " An association between the acute phase response and patterns of antigen induced T cell proliferation in juvenile idiopathic arthritis" ppt

Báo cáo y học: " An association between the acute phase response and patterns of antigen induced T cell proliferation in juvenile idiopathic arthritis" ppt

... response also favour the recruitment of a diverse memory T cell reper- toire to the joint, independent of the antigen specificity of the memory T cells. However, when there is little systemic inflammation ... through the gut or its mucosal associated lymphoid tissue, and exposed to enteric antigens, are preferentially able to bind to the syn- ovial endothelium and ar...
Ngày tải lên : 09/08/2014, 01:23
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Báo cáo y học: "spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response" doc

Báo cáo y học: "spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response" doc

... currently unclear whether the overexpression of IL-17 in inflammatory lesions of different autoimmune diseases indicates an extraordinary pathogenic role of this cytokine during inflammatory processes ... Pasero G, Veys E, Zeidler H, the European Spondylarthropathy Study Group: The European Spondylarthropathy Study Group preliminary criteria for the classification of spondylar...
Ngày tải lên : 12/08/2014, 17:21
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Báo cáo y học: " HTLV-1 HBZ cooperates with JunD to enhance transcription of the human telomerase reverse " pptx

Báo cáo y học: " HTLV-1 HBZ cooperates with JunD to enhance transcription of the human telomerase reverse " pptx

... present. Consequently, the activity of HBZ/JunD is independent of the DNA-binding properties of JunD, but instead requires the interaction of these bZIP factors with other nuclear factors. The proximal 180 bp of ... stimulating the transcriptional activity of the hTERT gene by HBZ together with JunD. However, the inspection of the nucleotide sequence of this re...
Ngày tải lên : 13/08/2014, 05:22
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Báo cáo y học: " Dendritic cell-mediated HIV-1 transmission to T cells of LAD-1 patients is impaired due to the defect in LFA-1" docx

Báo cáo y học: " Dendritic cell-mediated HIV-1 transmission to T cells of LAD-1 patients is impaired due to the defect in LFA-1" docx

... productive infection of CD4+ T lymphocytes by favoring cytosolic deliv- ery of viral material. J Virol 2003, 77:12299-12309. 39. Tardif MR, Tremblay MJ: Regulation of LFA-1 Activity through Cytoskeleton Remodeling ... Components Modu- lates the Efficiency of HIV Type-1 Entry in Activated CD4+ T Lymphocytes. J Immunol 2005, 175:926-935. 40. Tsunetsugu-Yokota Y, Yasuda S, Sugimoto A,...
Ngày tải lên : 13/08/2014, 09:20
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Báo cáo y học: " Intrahost variations in the envelope receptor-binding domain (RBD) of HTLV-1 and STLV-1 primary isolates" pot

Báo cáo y học: " Intrahost variations in the envelope receptor-binding domain (RBD) of HTLV-1 and STLV-1 primary isolates" pot

... nat- ural hosts. The rate of nonsynonymous changes per nonsynonymous site (dn) and the rate of synonymous changes per synony- mous site (ds) were calculated for the RBD sequences of each patient ... trans- mission of an optimally adapted form, rather than to an absence of replication or to a stricter polymerase fidelity of PTLV-1. Importantly, our new highly sensitive en...
Ngày tải lên : 13/08/2014, 09:21
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Báo cáo y học: " Reduced reliance on the trace element selenium during evolution of mammal" pps

Báo cáo y học: " Reduced reliance on the trace element selenium during evolution of mammal" pps

... may result in generation of reactive oxygen species that are capable of damaging selenoproteins. Therefore, the widespread use of these proteins in the face of high oxygen may be detrimental to ... both Sec -to- Cys and Cys -to- Sec directions that could then be compared with each other. With this approach, we detected 20 Sec -to- Cys transitions, but only two Cys -to- Sec trans...
Ngày tải lên : 14/08/2014, 08:21
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Báo cáo y học: "Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment" ppsx

Báo cáo y học: "Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment" ppsx

... to the number of unique peptide sequences they matched. Essentially, the A-index is a relative measure of the amounts of co-isolated proteins from the gel. We applied it as a convenient way to ... intensely focused data gathering to evaluate accuracy [13]. Here we address the issue of proteomic accuracy by intense exploration of a section of the budding yeast pro...
Ngày tải lên : 14/08/2014, 21:20
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Báo cáo y học: "Fish oil: what the prescriber needs to know" potx

Báo cáo y học: "Fish oil: what the prescriber needs to know" potx

... effect, attributable to EPA, is not seen with NSAIDs, which have no inhibitory effect on the 5-lipoxygenase pathway. Cytokines Other inflammatory mediators whose production is inhibited by fish oil are the cytokines ... because the ratios of these fatty acids in the tissues are determined largely by their ratios in the diet [1,2]. Dietary sources of n3 and n6 polyunsaturated f...
Ngày tải lên : 09/08/2014, 07:20
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Báo cáo y học: "olutionary divergence in the fungal response to fluconazole revealed by soft clustering" pptx

Báo cáo y học: "olutionary divergence in the fungal response to fluconazole revealed by soft clustering" pptx

... material. The second reason relates to the environment: it is very difficult to mirror in the l aboratory the range of conditions that must be experienced by yeast in the wild during the evolution ... infections is the family of chemical compounds known as the azoles, which interfere with formation of the cell membrane by inhibiting s ynthesis of ergoster ol [4]....
Ngày tải lên : 09/08/2014, 20:22
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