Báo cáo y học: "cGlobal analysis of microRNA target gene expression reveals the potential roles of microRNAs in maintaining tissue identity" ppsx
Báo cáo y học: "cGlobal analysis of microRNA target gene expression reveals the potential roles of microRNAs in maintaining tissue identity" ppsx
... Marrow Spleen Lymph node Bladder Thymus Brown fat 0.1 1 10 0 b RR value 141 microRNAs Figure 4 1 Global analysis of microRNA target gene expression reveals the potential roles of microRNAs in maintaining tissue identity ZhenbaoYu * ,ZhaofengJian,Shi-HsiangShen,EnricoPurisima,andEdwinWang * BiotechnologyResearchInstitute,NationalResearchCouncil of Canada,Montréal,...
Ngày tải lên: 14/08/2014, 16:20
Báo cáo y học: "inferring steady state single-cell gene expression distributions from analysis of mesoscopic samples" docx
... analyzed, the software (as R code), and instructions, explicitly described by the "README" file in the archiveAZIP file containing the qRT-PCR data analyzed in this manu-script, the software ... experimentally accessible numbers of cells. This suggests that other stochastic events occurring in single cells, even complex interactions in path- ways, may reveal them...
Ngày tải lên: 14/08/2014, 17:22
Báo cáo hóa học: " cDNA targets improve whole blood gene expression profiling and enhance detection of pharmocodynamic biomarkers: a quantitative platform analysis" ppt
... contributed to the study design, participated in the expression profiling assays and participated in the ex vivo dosing study. DA participated in the expression profiling assays and participated in the ... assisted with the data analysis and participated in drafting and editing of the manuscript. SL completed the analysis of the protocol selection study...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo y học: "Hereditary angioedema: beyond international consensus - circa December 2010 - The Canadian Society of Allergy and Clinical Immunology Dr. David McCourtie Lecture" pps
... recently pub- lished in HAE prophylaxis and therapy and these have led to the licensing of pdC1INH (Berinert ® ,CSLBehr- ing; Cinryze ® , ViroP harma; Ceto r-n ® , Sanquin) in many parts of the ... C1 INHIBITOR (C1INH) If “failing” on demand therapy with any of the angioedema event therapies (AERx’s; pdC1INH, rhC1INH, bradykinin B2 receptor antagonist, kallikrein inhibi...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "Passage and reversal effects on gene expression of bovine meniscal fibrochondrocytes" pdf
... described in the study, in addition to drafting the initial version of the manuscript. KAA supervised the study and oversaw the drafting of the manuscript. Both authors read and approved the final ... However, the phenotype of these cells may be significantly different from that of the primary population. The objective of this study was to investigate changes...
Ngày tải lên: 09/08/2014, 10:21
Báo cáo y học: "Introducing Arthritis Research & Therapy’s 10th anniversary issue, ‘The Scientific Basis of Rheumatology: A Decade of Progress’" pdf
... Therapy to denote the journal’s aim of incorporating translational aspects of rheumatology within its pages. In the decade since the first biologic agents – infliximab and etanercept – were introduced ... review of the remarkable progress in rheumatology in the past decade. We hope it will not only give the basic investigator a comprehensive overview of the state...
Ngày tải lên: 09/08/2014, 13:22
Báo cáo y học: " Adjuncts or adversaries to shared decision-making? Applying the Integrative Model of behavior to the role and design of decision support interventions in healthcare interactions" pps
... populations, the effect may be attitudinally driven, whereas in others it may be normatively driven. However, by only measuring the central constructs of the IM one does not gain any insight into the ... applied in many health contexts over the past 30 years. [21]. These include the Theory of Reasoned Action, the Theory of Planned Behavior, the Health Belief Model an...
Ngày tải lên: 11/08/2014, 05:21
Báo cáo y học: " GM-CSF and IL-2 as adjuvant enhance the immune effect of protein vaccine against foot-and-mouth disease" pot
... showed the highest level of mRNAs of either Th1 or Th2 cytokines. Expression of the cytokines in the groups with single cytokine co-expressed or mixed with VP1 showed the same level of either Th1 ... modulate the immune responses induced by subunit vaccine. In many studies cytokines were used to reinforce the ability of the subunit vaccine to induce antigen-speci...
Ngày tải lên: 11/08/2014, 21:21
Báo cáo y học: " Human Immunodeficiency Virus Type 1 Nef protein modulates the lipid composition of virions and host cell membrane microdomains" pot
... highly enriched in the unusual sphingolipid dihydrosphingomyelin (DHSM) and inhibition of sphingolipid synthesis resulted in a 5- fold reduction in virion infectivity [38]. The magnitude of this ... tuned down in the presence of the viral protein [10-14]. Finally, during production of progeny virus, Nef augments the intrinsic infectivity of cell-free HIV particles...
Ngày tải lên: 13/08/2014, 05:22
Báo cáo y học: "Patients with allergic rhinitis and allergic asthma share the same pattern of eosinophil and neutrophil degranulation after allergen challenge" pdf
... primarily tis- sue-residi ng cells in the hematopoietic organs as well as in the airways, the gastrointestinal tract and the skin. The physiological function of the eosinophils is not completely understood, ... just in severe chronic stages of the disease, but also in mild disease. Additionally, the recent advances using anti-IL-5 therapy indicate involvement of...
Ngày tải lên: 13/08/2014, 13:22