Báo cáo y học: " From single cells to whole organism" pps

... completely sequenced, phylogenetic occurrence profiles now provide an additional tool to extend their functional annotation. Using data obtained by mass spectrometry and peptide arrays, Tony Pawson ... sustain living systems has always been the ultimate goal in biology, and solutions are now coming from the relatively new discipline of systems biology. The essence of systems biology lies...

Ngày tải lên: 14/08/2014, 16:20

... by maternal autoantibod- ies. Although the pathways of clearance and cytokine secretion may vary, these scavengers phagocytose both nonopsonized and opsonized apoptotic cells. Concomi- tantly ... merely a common final pathway of inflammation. It seems reasonable to predict that there are both suscep- tibility and regulatory factors, such as fetal polymorphisms of Fc receptors and cytokines...

Ngày tải lên: 09/08/2014, 01:22

... inflammation from performing their regulatory function by pro-inflammatory cytokines. Similarly, although shown only for peripheral blood, it has been suggested that CD4 + CD25 + T cells display functional differences ... of CD4 + CD25 + T cells in the rheumatic joint might relate to the fact that inflammatory cytokines such as IL-2 and costimulatory molecules cause CD4 + CD25 + T ce...

Ngày tải lên: 09/08/2014, 06:22

... stimulation by pathogen compo- nents (such as LPS) may polarize MP towards the cytotoxic phenotype. A predominantly regulatory response is then mounted by the host, mediated by alternative cytokines ... junc- tions, cytotoxic molecules, migratory markers) is essentially bimodal. This polarization program turns MPs to a 'cytotoxic' or a 'symbiotic' phenotype [18]. In phys...

Ngày tải lên: 14/08/2014, 14:21

... at pH 4.0 and 7.0, respectively. Flow cytometry analysis The competitive effect of Yb-Tf species on binding of Fe 2 -Tf to K562 cells was studied by flow cytometry. The solutions with a constant ... study of uptake of Yb 3+ by human Tf (hTf) by UV-vis and NMR spectroscopy, and inductively coupled plasma atomic emission spectro- metry (ICP-AES). The binding of Yb-bound Tf to human erythro...

Ngày tải lên: 08/03/2014, 09:20

... summaries for topic "US Drought of 1988". From Single to Multi-document Summarization: A Prototype System and its Evaluation Chin-Yew Lin and Eduard Hovy University of Southern ... following date expressions: • weekdays (Sunday, Monday, etc); • (past | next | coming) + weekdays; • today, yesterday, last night. We then order the summary sentences in their chronologica...

Ngày tải lên: 17/03/2014, 08:20

... of the holoenzyme by 11 °C, makes it resistant to tryptic hydrolysis and prevents the precipitation observed with the wild-type apoenzyme demonstrates that the absence of this lysine residue, ... internal aldimine lysine (K42) in O-acetylserine sulfhydrylase to alanine indicates its importance in transamination and as a general base catalyst. Biochemistry 35, 13485–13493. 7. Toney, M.D. &...

Ngày tải lên: 31/03/2014, 08:20

... recording from only one cell per dish, so that the birtoxin and ikitoxin effects reported here were obtained from cells that had not previously been exposed to any Na + channel toxin. All toxins ... activity of this toxin in a unique way to result in reduced potency in mice. The C-termini of scorpion toxins are hypothesized to be responsible for a significant portion of their toxic...

Ngày tải lên: 31/03/2014, 08:20

Ngày tải lên: 09/08/2014, 01:21

... allowed to adhere overnight under normoxia. HIF-1α inhibitor, namely 3-(5'-hydroxymethyl- 2'furyl)-1-benzyl indazole (YC-1; Calbiochem, Nottingham, UK), in dimethylsulphoxide was added to ... 5'-3'AGAGAAAGAAAAAGGGAAAGGTAAGTTT COL1A2, collagen type I alpha 2; COL2A1, collagen type II alpha 1; HIF, hypoxia inducible factor; P4H, prolyl 4-hydroxylase; PHD, HIF prolyl hyd...

Ngày tải lên: 09/08/2014, 10:20