Báo cáo y học: "New developments in developmental biology" doc

... morphological variations including armor plates, fins and spines. Divergent populations of these fish that do not normally interbreed in the wild can be crossed in the laboratory to map evolutionary variation in morphological ... resemble a hindlimb, suggesting that this gene is involved in specifying limb iden- tity. Barry Dickson (Institute of Molecular Biotechnology, Vienna, Austri...

Ngày tải lên: 14/08/2014, 16:20

... to target key cytokines implicated in JIA, including TNFα, IL-1, IL-6 as well as signaling molecules involved in the regulation of B-cell and T-cell lymphocyte responses (Table 4). Although promising ... Wallace CA, Chon Y, Lin SL, Baum- gartner SW, Giannini EH, Pediatric Rheumatology Collaborative Study Group: Safety and efficacy of up to eight years of con- tinuous etanercept therapy...

Ngày tải lên: 09/08/2014, 01:22

... implicated in the mediation of endogenous pain inhibitory mechanisms through the descending inhibitory pain pathways in the brain and spinal cord [8-10]. Dysfunction in serotonin and nor- epinephrine in ... treatments beginning once weekly, followed by twice weekly, and finally three times weekly. Clinically meaningful treatment response, defined by a 30% improvement in pain, occurr...

Ngày tải lên: 09/08/2014, 08:22

... (CIA) in mice, indicating that inter- action between CD97 and its ligands may be involved in cell migration in arthritis [21]. CD97 is expressed by inflammatory cells, mainly leukocytes, in RA synovium ... (reviewed in [85]). Other polymorphic genes thought to be involved in RA include protein tyrosine phosphatase N22 (PTPN22), CTLA4, peptidyl arginine deiminase type IV and macrop...

Ngày tải lên: 09/08/2014, 10:22

... training and education necessary to carry out these tasks, and to ensure that these skills are fully uti- lised in practice. Although podiatric surgeons already pos- sess the necessary training ... of uniformity (at least in principle) [14]. Ini- tially within this scheme (as far as medicines are con- cerned) individual state poisons regulations will still apply, which will delay Australi...

Ngày tải lên: 10/08/2014, 21:24

... protein acidic, cysteine- rich) are new. Secretory leukocyte peptidase inhibitor I, which downregulates TNF, could be an interesting target for future studies. Secreted protein acidic, cysteine-rich ... understanding of the different pathways to inflammation will facilitate the assessment of disease activity and will improve targeting of therapies [5]. Abbreviations AS = ankylosing spond...

Ngày tải lên: 12/08/2014, 11:22

... iso- niazid, during infection-control of growth-reinfection cycles, also explains how therapy for only nine months with a single drug, effective only against actively dividing bacilli, is highly effective ... van Soolingen D, Raupach B, Kaufmann SH: Increased vaccine efficacy against tuberculosis of recombinant Mycobacterium bovis bacille Calmette- Guerrin mutants that secrete listeriolysin....

Ngày tải lên: 12/08/2014, 13:22

... fertiliz- ers, reducing the greenhouse effect, maintaining small farming communities, preserving biodiversity. It is clear that legumes can provide a solution: in terms of protein content they are amongst ... con- trary to early concerns, having two model legumes does not necessarily lead to a duplication of results but, in fact, often leads to an acceleration of research by creating com-...

Ngày tải lên: 14/08/2014, 14:21

... impor- tant for functional protein analysis. Experimental approaches to determining topology usually deal with proteins individually and are very time-consuming. In contrast, Daley et al. [4] first used ... proteins out of the 737 proteins was determined by finding their homologs among the 502 exper- imentally determined proteins. When the resulting set of 601 proteins was compared with 71...

Ngày tải lên: 14/08/2014, 16:20

... domain) Kit ligand Leptin Matrix extracellular phosphoglycoprotein with ASARM motif (bone) MyoD family inhibitor Nonagouti Oncostatin M Programmed cell death 1 TYRO protein tyrosine kinase binding ... phenotype Behavior/neurological phenotype Reproductive system phenotyp e Endocrine/exocrine gland phenotype Cardiovascular system phenotype Vision/eye phe notype Craniofacial phenotype Respirato...

Ngày tải lên: 14/08/2014, 20:22