Báo cáo y học: "hese authors contributed equally to this" docx

... including mature parasite-infected erythrocyte surface antigen (MESA - known to bind to the erythrocyte membrane cytoskeleton) http://genomebiology.com/2005/6/11/R93 Genome Biology 2005, Volume 6, Issue 11, ... the erythrocyte mem- brane and mediate cytoadhesion to human receptors exposed to circulating parasites. PfEMP1 proteins are encoded by var genes, and field isolates possess ap...

Ngày tải lên: 14/08/2014, 15:20

... microarray hybridization and array scanning were performed as previously described [21]. Briefly, 25 μg of total RNA was used to isolate the low molecular weight RNA using polyethylene glycol solution ... Palaeontology and Geology, East Beijing Road, Nanjing, Jiangsu 210008, PR China. ¤ These authors contributed equally to this work. Correspondence: Junfeng Zhang. Email: jfzhang@n...

Ngày tải lên: 14/08/2014, 21:20

... Tschopp J: Inflammatory caspases: linking an intra- cellular innate immune system to autoinflammatory diseases. Cell 2004, 117:561-574. 33. Martinon F, Tschopp J: Inflammatory caspases and inflammas- omes: ... activates transcription factors such as nuclear factor-κB (NF-κB) and interferon regulatory factors (IRFs) that ultimately lead to tumor necrosis factor (TNF) and type I interferon...

Ngày tải lên: 14/08/2014, 20:22

... mediates Myc autorepression and its tran- scriptional control at many loci. In this study the authors used the Gal4 UAS system to express ectopic dmyc in embryos and performed microarray analysis to ... cuticle hydrolase activity transferase activity ion transporter activity carrier activity structural constituent of cytoeskeleton microtubule motor activity nucleoside binding hydrolase...

Ngày tải lên: 14/08/2014, 20:22

... the capacity to systematically assess preventable adverse events, which are defined as poor outcomes caused by errors or system design flaws. We describe how we used MET calls to systematically identify ... Emergency Teams (METs), alternatively known as Rapid Response Teams, have recently been implemented in many hospitals worldwide [1]. The primary role of an MET is to improve the earl...

Ngày tải lên: 25/10/2012, 10:06

... mainly cytostati- cally compared with classical cytotoxic drugs require special timing of scans [68]. International guidelines for PET tests are therefore necessary to guarantee the quality and ... conditions, are likely to play a key role in future clinical cancer treatment. Table 2. Tumor types for which FDG-PET assays are used to assess tumor response to cancer drug therapy...

Ngày tải lên: 25/10/2012, 11:10

... Introduction Cystatin C (Cys-C) is a non-glycosylated cationic protein of 13.3 kDa, belonging to the cystatin superfamily of cysteine protease inhibitors [1, 2]. Cys-C is produced by all nucleated ... is secreted into the blood at a constant rate [1, 2]. Cys-C is freely filtered through the normal glomerular membrane and completely reabsorbed, followed by catabolization by the proxim...

Ngày tải lên: 31/10/2012, 17:08

... in the hydroxylases. The mutation of these residues in the desaturases to the corresponding hydroxylase residues resulted in the conversion of desaturase activity to hydroxy- lase activity. The ... into factors contributing to substrate specificity of membrane-bound 3-ketoacyl-CoA synthases Brenda J. Blacklock and Jan G. Jaworski Department of Chemistry and Biochemistry, Miami University...

Ngày tải lên: 21/02/2014, 15:20

... atively unfo lded proteins is i ndirectly con- ®rmed by their extremely h igh s ensitivity to protease degradation in vit ro [4,5,54±59]. Table 1. Hydrodynamic characteristics of the natively unfolded ... 24.6 Cytochrome c 11.7 4.05 Ribonuclease A 13.7 32.4 [41] Lysozyme 14.2 33.1 [41] Hemoglobin 15.5 33.5 Myoglobin 16.9 35.1 b-Lactoglobulin 18.5 37.8 [41] Chymotrypsinogen 25.7 45 [41] Carb...

Ngày tải lên: 08/03/2014, 16:20

... undecaprenyl pyrophosphate synthase; DDPPS, dehydrodolichyl pyrophosphate synthase; PPPS, polyprenyl pyrophosphate synthase; GPPS, geranyl pyrophosphate synthase; FPPS, farnesyl pyrophosphate synthase; ... geranylgeranyl pyrophosphate synthase; FGPPS, farnesylgeranyl pyrophosphate synthase; HexPPS, hexa- prenyl pyrophosphate synthase; HepPPS, heptaprenyl pyrophosphate synthase; OPPS, octapren...

Ngày tải lên: 08/03/2014, 22:20