Báo cáo y học: "hromatin dynamics rule the genome" ppsx

... mediated by Spt6 following the passage of RNA polymerase II may prevent transcription from these cryptic promoters. One of us (J.W.) discussed the role of the Rpd3 small histone deacetylase complex ... containing the Ubx gene, thus allowing the Poly- comb group proteins bound to the PRE to methylate the entire gene. While PREs are not intrinsically able to cluster in the nucle...

Ngày tải lên: 14/08/2014, 15:20

Ngày tải lên: 13/08/2014, 21:21

... SUPERFAMILY domain classes in prokaryotes, used to generate the cost function in the model with specificity. On the x-axis, domain families are ordered by the fraction of genomes they occur in. The y- axis ... that the domain class distributions are power laws. They have explored two main directions, a 'designability' hypothesis and a 'genome growth' hypothes...

Ngày tải lên: 14/08/2014, 21:20

... which the true mortality rate actually lies. In practice, investigators usually use the 95% CI, the range that includes the true mortality rate 95% of the time. The narrower the CI, the closer the ... tolls by multiplying the observed excess mortality rate (and its CI) by the length of the recall period, and by the estimated total population. The DRC study authors...

Ngày tải lên: 25/10/2012, 10:31

... medical conditions may be delayed. As the physician with the most (and often the only) contact with these patients, psychiatrists need to be vigilant in detecting early signs and symptoms of medical illness ... bipolar disorder in the general population are likely receiving even less medical care. The significance of this finding is that the psychiatrist may be the only physicia...

Ngày tải lên: 25/10/2012, 10:51

... due to its methyltransferase activity or the interaction with the PRB motif. Further studies with a methyl- transferase inhibitor specific for the PR domain may help to understand the exact mechanism ... RIZ1 varies over the progression of cancer; and the second question is whether the PR domain alone possesses anticancer activity. In this study, we quan- titatively analyz...

Ngày tải lên: 25/10/2012, 11:15

... During the therapeutic process, real-time estimation of the therapeutic effect was carried out by the computer system through the graphic changes in the target field and the hyperecho of the ... recovered rapidly. In the present study, the amylase levels in the serum and urine were increased in the first 3 days and the first 5 days after HIFU ab- lation, respecti...

Ngày tải lên: 25/10/2012, 11:18

... experience with the management of disseminated disease is very limited in the literature 6 , therefore, attention to the therapy strategy of this neoplasm in the future may allow a more reasonable ... result in the uncertainty of the strategy for its treatment. While further delineati n g the clinicopathological and radiological features, and summarizing the surgical thera...

Ngày tải lên: 25/10/2012, 11:40

... Gln/Gln genotype vs. Lys/Lys genotype). There was no interaction between smoking (smoking status, pack-years and duration) and the polymorphism [14, 19, 26, 27]. Although the Lys/Lys genotype was ... between the Lys751Gln polymorphism and lung cancer was found in the two meta-analyses [51]. These meta-analyses indicate that the excess lung cancer risk from the Gln/Gln gen...

Ngày tải lên: 31/10/2012, 14:59

... represent any risk for infection with Toxoplasma gondii. Cats are the definitive host of T. gondii; they are the only animals that pass oocysts in their feces. They become infected by eating ... with the need to explain to their clients that it is not necessary, for example, to give away one’s cat during pregnancy and that if they follow a few very simple “rules”, liv- ing with th...

Ngày tải lên: 03/11/2012, 11:06