Báo cáo y học: "Explicit equilibrium modeling of transcription-factor binding and gene regulation" pdf
Báo cáo y học: "Explicit equilibrium modeling of transcription-factor binding and gene regulation" pdf
... experimentally, for example by binding site selection [29] or by computa- tional analysis of co-regulated genes [2,30,31], or by a combi- nation of selection and computational analysis [23]. Typically, ... cooperative binding of proteins X and Y to DNA can be separated thermodynamically into the formation of an XY dimer and the binding of that dimer to DNA; this is the...
Ngày tải lên: 14/08/2014, 14:22
Báo cáo y học: "Predictive network modeling of the highresolution dynamic plant transcriptome in response to nitrate" pps
... 15, and 20 minu tes are 63 (76% of regu- lated genes), 146 (76% of regulated genes), 54 (98% of regulated genes), 123 (82% of regulated genes), 164 (87% of regulated genes), and 209 (92% of regulated ... upon perturbation. Such dynamical models essentially consist of a mathematical function that governs the transitions of the state of a gene regulatory network over tim...
Ngày tải lên: 09/08/2014, 22:23
Tài liệu Báo cáo Y học: Biphasic reductive unfolding of ribonuclease A is temperature dependent pdf
... image analysis, which is established by us recently [4,11], was used to analyze the unfolding dynamics and also was introduced into the analysis of the thermal transition study by CD and 1 HNMR. MATERIALS ... mutants of bovine pancreatic ribonuclease A missing the 65–72 disulfide bond: characterization of a minor folding pathway of ribonuclease A and kinetic roles of Cys65 and...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: NMR-based determination of the binding epitope and conformational analysis of MUC-1 glycopeptides and peptides bound to the breast cancer-selective monoclonal antibody SM3 pptx
... fragment of the ligand of the X-ray structure (RCSB PDB entry 1SM3). After small manual corrections, t he ligands were docked into the binding site of SM3 using the FLEXIDOCK module of t he SYBYL software ... monoclonal antibody SM3, which is being tested for its diagnostic utility. We used NMR spectroscopy to analyze the binding mode and t he binding epitope of peptide and...
Ngày tải lên: 21/02/2014, 15:20
Báo cáo y học: "The factor structure of the Strengths and Difficulties Questionnaire (SDQ) in Greek adolescents" potx
... Equation Modeling 1999, 6:1-55. 39. Nunnally JC, Bernstein IR: Psychometric theory. New York, USA: McGraw-Hill Book Company; 1994. Annals of General Psychiatry 2009, 8:20 http://www.annals-general-psychiatry.com/content/8/1/20 Page ... 2 Department of Child and Adolescent Psychiatry, Athens University Medical School, "Agia Sophia" Children's Hospital, Athens, Greece...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: " A promoter haplotype of the interleukin-18 gene is associated with juvenile idiopathic arthritis in the Japanese population" pps
... the polyarthritis and systemic subgroups, the frequency of haplotype S01 did not differ statistically from that of healthy controls. The frequency of haplotype S01 was also significantly higher ... fre- quency of haplotype S01 of the IL18 gene is 37.9% and that of the S01/S01 diplotype configuration is 13.9% in the Japa- nese population. We also estimated the frequency of...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Chondrogenic differentiation potential of osteoarthritic chondrocytes and their possible use in matrix-associated autologous chondrocyte transplantation" pot
... OA and ND chondrocytes, and only 184 genes were differentially regulated. Conclusions Only few genes were differentially expressed between OA and ND chondrocytes in Hyaff-11 culture. The risk of ... high-density pellet and scaffold (Hyaff-11) cultures by histological proteoglycan assessment (Bern Score) and immunohistochemistry for collagen types I and II. Chondrocytes cultured...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: "Genome-wide prioritization of disease genes and identification of disease-disease associations from an integrated human functional linkage network" pps
... network; GO: Gene Ontology; GS: gold standard; GSP: gold standard positive; GSN: gold standard negative; GN: gene neighbour; HPRD: Human Protein Reference Database; KEGG: Kyoto Encyclopaedia of Genes and ... will subsequently refer to this set of 334 genes as 'ObesHancock' genes. There is no overlap between the 24 OMIM obesity genes and the 334 ObesHancock genes. Here, w...
Ngày tải lên: 09/08/2014, 20:20
Báo cáo y học: " Contrasting chromatin organization of CpG islands and exons in the human genome" pot
... density of H3K36me3 does not show exon-specific enrichment. My hypothesis is as follows. The relative density of H3K36me3 differs between highly and lowly expressed genes. It is the den- sity of ... methylation patterns and epigenetic memory. Genes Dev 2002, 16:6-21. 26. Yamada Y, Watanabe H, Miura F, Soejima H, Uchiyama M, Iwasaka T, Mukai T, Sakaki Y, Ito T: A comprehensive an...
Ngày tải lên: 09/08/2014, 20:22
Báo cáo y học: " An exploratory survey of money boys and HIV transmission risk in Jilin Province, PR China" potx
... that rural money boys may increase condom usage after migrating to large cities [17]. The very nature of the MB trade would imply that they seek multiple sexual part- ners, and may yield to client ... suggest that migrants may not necessarily be at the heart of money boy activity in Jilin Province. This finding is potentially important, since there is always a danger of increased soci...
Ngày tải lên: 10/08/2014, 05:21