Báo cáo y học: "The dog and rat olfactory receptor repertoires" doc
... showing the number of rat and dog OR genes and pseudogenes per family and subfamilyA spreadsheet showing the number of rat and dog OR genes and pseudogenes per family and subfamily. Families 2 to ... respectively) included fewer pseudogenes (17% and 13% for dog and rat, respectively) than class II (23% and 20% pseudogenes for dog and rat, respectively). Even...
Ngày tải lên: 14/08/2014, 14:22
... sequencer using the Big Dye terminator sequencing kit (Perkin-Elmer, Applied Biosystem Division). Gibco BRL and Integrated DNA Technology synthesized custom primers. Assembly and analysis of the DNA sequences ... extracted by 70% ethanol from the cell pellets. The extracts were concentrated by rotary evaporation, and lipids and proteins were then removed by the addition of a mixture o...
Ngày tải lên: 17/03/2014, 17:20
... extended by BLV RT by only one nucleotide beyond the mismatched 3¢ end may explain, at least in p art, why virions of BLV grown in culture show a relatively low mutation rate per replication cycle ... processivity and fidelity of DNA synthesis exhibited by the reverse transcriptase of bovine leukemia virus Orna Avidan, Michal Entin Meer, Iris Oz and Amnon Hizi Department of Cell Biology a...
Ngày tải lên: 31/03/2014, 21:21
Báo cáo y học: "The use and abuse of commercial kits used to detect autoantibodies" ppsx
... manufacturers operate under a high level of security, of scrutiny and of standardization, and under good labora- tory practices and quality control. Many of these compa- nies subscribe to and offer ... difficult to understand why low-cost and high-quality autoimmune serology is not given a higher priority by the health care system. It is appreciated that inappropriate laboratory tes...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "The role and clinical implications of G6PI in experimental models of rheumatoid arthritis" pptx
... autoreactive lymphocytes trigger macrophages, synoviocytes and other effector cells that mediate synovitis and the destruction of cartilage and bone [1–7]. B and T lymphocytes in rheumatoid arthritis and ... unanswered. Why the joint? It is currently unclear why systemic autoreactivity against the ubiquitously expressed glycolytic enzyme G6PI specifically induces arthritis, with no...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "The identification and characterization of a novel protein, c19orf10, in the synovium" docx
... all of the protein is necessarily glycosylated. Eight potential phosphorylation sites at residues S33, S84, S132, S169, T36, Y6 1, Y6 7, and Y1 19 are predicted by the NetPhos 2.0 server [22]. These ... of fibroblast-like synoviocytes (FLSs) and macrophages. These cells produce glycosaminoglycans such as hyaluronic acid and lubricating glycoproteins for secretion into the synovial fl...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "The biological and clinical importance of the ‘new generation’ cytokines in rheumatic diseases" pot
... reduces chondrocyte proliferation, upregulates inducible NO synthase, stromelysin, and cyclooxygenase 2 (COX2) expression, and increases glycosaminoglycan release. IL-18 further promotes synovial chemokine ... cells promoting cytokine release and cytotoxic function. Th1 and Th17 cells proliferate and produce cytokine to IL-15 and exhibit prolonged survival, and in B cells, isoty...
Ngày tải lên: 09/08/2014, 14:20
Báo cáo y học: "The promise and reality of personal genomics" pot
... likely to be easy to both genotype and sequence. The sensitivity of SNP and indel detection in repetitive or copy-number-variable regions will be lower. Finally, a non-trivial proportion of any ... (Solexa) [4] and Applied Biosystem’s SOLiD [5] systems - but no explicit comparison of the two versions has yet been published. Minireview The promise and reality of personal genomics...
Ngày tải lên: 09/08/2014, 20:20
Báo cáo y học: " The dog days of autumn" pptx
... most coat phenotypes in pure- bred dogs in the United States. Clifford: You mean my coat is controlled by just three genes? Mink: Maybe not. They only looked at purebreds, and you’re a mixture ... length, and the presence or absence of what they call ‘furnishings’ - you know, that little moustache and bushy eyebrows you have. Clifford (proudly): I am well furnished. Mink: Of course...
Ngày tải lên: 09/08/2014, 20:20
Báo cáo y học: " The yin and yang of chromatin spatial organization" ppt
... Fullwood MJ, Liu MH, Pan YF, Liu J, Xu H, Mohamed YB, Orlov YL, Velkov S, Ho A, Mei PH, Chew EG, Huang PY, Welboren WJ, Han Y, Ooi HS, Ariyaratne PN, Vega VB, Luo Y, Tan PY, Choy PY, Wansa KD, Zhao ... Horton A, Wood AL, Bolland DJ, Corcoran AE, Fraser P: Myc dynamically and preferentially relocates to a transcription factory occupied by IgH. PLoS Biol 2007, 5:e192. 18. Lin C, Yang L,...
Ngày tải lên: 09/08/2014, 20:21