Báo cáo y học: "Putting the ‘bio’ into bioinformatics" ppsx

... of the functional behavior of the physiological state of an individual or species. The heart physiome project is currently constructing integrated models from the molec- ular level all the way ... the way to the whole-organ scale, some func- tioning on the microsecond timescale and others changing slowly throughout the human lifetime. The meeting clearly showed how state-o...

Ngày tải lên: 14/08/2014, 14:22

... 3-hydroxy-3-methylglutaryl-coenzyme A; IFN = interferon; i.p. = intraperitoneally; LPS = lipopolysaccharide; Th = T helper cell; TNF = tumour necrosis factor. Arthritis Research & Therapy ... 4 Hall The recognition that systemic inflammatory diseases are associated with accelerated atherosclerosis offers the prospect of reducing morbidity and mortality of affected patients by attentio...

Ngày tải lên: 09/08/2014, 01:23

... as determined by forward and sideward scatter, analyzed by flow cytometry (left panel, the histograms were obtained by gating on dead or live cells, as indicated by the arrows in the scatter plot). ... determined by forward and side- ward scatter, was analyzed by flow cytometry (left panel, the histograms were obtained by gating on dead or live cells, as indicated by the arrows in...

Ngày tải lên: 12/08/2014, 23:23

... the multivariate analysis. It is the change in serum lactate, between the first measurement in the community and the second on hospital arrival, that is independently associated with death. The ... blood samples analysed in the prehospital environment and subsequent hospital mortality. These preliminary data indicate a promising avenue of research into the treatment of haemo...

Ngày tải lên: 13/08/2014, 11:23

... in the Philippines, Egypt, Chile, and India. Inj Control Saf Promot 2004, 11:125-129. 20. Marcolino JA, Iacoponi E: The early impact of therapeutic alliance in brief psychodynamic psychotherapy. ... provided at primary level during emergencies can potentially improve patients’ symptoms of distress. The key t o suc- cess in this project lies in the flexibility given by the mobile set...

Ngày tải lên: 13/08/2014, 15:21

... limited by the fact that several variables other than diagnoses have been reviewed to evaluate the comparability of the two sam- ples. Additionally the first author of the study was the only Kid- die-SADS ... category (12 to 17 years old). Since the unit is the only facility in the country providing psychiatric in-patient treatment for adolescents, we assume that our populat...

Ngày tải lên: 13/08/2014, 18:21

... anticipated. These factors significantly reduced the power of the study. Based on their findings, the authors estimate that more than 100 hospitals would be needed to show the 30% difference they sought. ... seen from baseline to the study period for both groups combined. Conclusion The MET system greatly increases emergency team calling, but does not substantially affect...

Ngày tải lên: 25/10/2012, 10:39

... series will probably be familiar, it is hoped that there will still be useful lessons to be learned, for example the underlying assumptions of a hypothesis test that were not fully appreciated, or ... some previously unrecognised confusion between terms. The first article, presented in this issue, covers the presentation and summary of data. It is unlikely that the material covered by...

Ngày tải lên: 25/10/2012, 10:45

... the catalytic efficiency of the enzyme, the cold adaptation of the enzyme could not be attributed to the presence of the Gly cluster in this element. The present study supports the idea that the ... Gly261 by Ala in mutant G261A resulted in an enzyme with slightly lower stability. On the other hand, in the double mutant G261A /Y2 69A the additional replacement of Tyr269...

Ngày tải lên: 22/02/2014, 04:20

... guanidine hydro- chloride (GdnHCl), urea or elevated temperatures, they destroy the tertiary structure of proteins which results in the loss of enzymatic activity. Regarding the secondary struc- ture ... triflu- oroethanol the proteolytic susceptibility of RNase A strongly increases, which coincides with the disruption of the tertiary structure of the RNase A molecule, in 20% tri...

Ngày tải lên: 22/02/2014, 07:20