Báo cáo y học: " L2L: a simple tool for discovering the hidden significance in microarray expression data" pdf
Báo cáo y học: " L2L: a simple tool for discovering the hidden significance in microarray expression data" pdf
... well-defined perturbation may lead immediately to a hypothesis regarding the underlying mechanism in the system under study. L2L is a database and associated software tool (Figure 1a) that systematically compares the ... D, Barrette T, Pandey A, Chinnaiyan AM: ONCOMINE: a cancer microarray database and integrated data-mining platform. Neoplasia 2004, 6:1-6. 13. Edgar R, Dom...
Ngày tải lên: 14/08/2014, 14:22
Báo cáo y học: " NeMeSys: a biological resource for narrowing the gap between sequence and function in the human pathogen Neisseria meningitid" pot
... (approxi- mately 90%) are shared (Additional data file 3) since they encode proteins displaying at least 30% amino acid identity over at least 80% of their length and are, in addition, in syn- teny ... recombi- nation [44]. In conclusion, the fact that approximately 90% of meningococcal genes are conserved in clinical isolates is a clear advantage for NeMeSys as it indicates tha...
Ngày tải lên: 09/08/2014, 20:20
Báo cáo y học: " Pruritus: a useful sign for predicting the haemodynamic changes that occur following administration of vancomycin" ppsx
... the coronary patients were adequately monitored and the anaes- thetist was therefore in the optimal conditions to detect and treat any change in cardiorespiratory function at an early stage. Our analysis ... pulmonary artery catheter [Arrow AH 050050-H, 7.5 F; Arrow International, Inc., Reading, PA, USA] transcuta- neous oxygen saturation probe), vancomycin (15 mg/kg) was administer...
Ngày tải lên: 12/08/2014, 18:21
Báo cáo y học: "Can a simple blood test quantify brain injury" ppsx
... have intensified in the past few years. Early candidates for brain injury biomarkers included lactate dehydrogenase and creatinine kinase enzyme subtypes in the serum and cerebrospinal fluid. These ... specific pathogenic pathways. Others, such as hypothermia for the treatment of brain injury after cardiac arrest, have multiple additive and synergistic mechanisms of action that...
Ngày tải lên: 13/08/2014, 16:21
Báo cáo y học: "NGAL: an emerging tool for predicting severity of AKI is easily detected by a clinical assay" potx
... a research ELISA, is an early predictive biomarker of acute kidney injury (AKI) after cardiopulmonary bypass (CPB). e availability of a standardized clinical platform for NGAL measurements ... an ongoing search to identify early biomarkers of AKI that would play a role similar to that of troponin in acute myocardial infarction. Neutrophil Gelatinase-Associated Lipocalin (NG...
Ngày tải lên: 13/08/2014, 20:22
Báo cáo y học: "Could a simple surgical intervention eliminate HIV infection?" pps
... [8]. They proposed that using a suitable immunosuppressant or CD4-killing drug in combination with an anti-viral therapy may eliminate the infection. This author has arrived at the same result independently using ... principle, the vaccination primes the system for a faster, stronger response, including proliferation of the respond- ing lymphocytes. As the same cells are t...
Ngày tải lên: 13/08/2014, 22:22
Báo cáo khoa học: TICL – a web tool for network-based interpretation of compound lists inferred by high-throughput metabolomics doc
... metabolic pathway. Another procedure (impact analysis) proposed recently by Draghici et al. [25,26] goes beyond gene pairs and fully captures the topology of signaling pathways by propagating the ... KEGG atlas mapping for global analysis of metabolic pathways. Nucleic Acids Res 36, W423–W426. 34 Hooper SD & Bork P (2005) Medusa: a simple tool for interaction graph analysis....
Ngày tải lên: 16/03/2014, 01:20
Báo cáo Y học: Barley a-amylase Met53 situated at the high-affinity subsite )2 belongs to a substrate binding motif in the bfia loop 2 of the catalytic (b/a)8-barrel and is critical for activity and substrate specificity pot
... TAA (in black). The superimpositioning was guided by the catalytic acids (D179 AMY2 , E204 AMY2 , and D289 AMY2 and D206 TAA , E230 TAA , and D297 TAA ). The invariant Y5 1 AMY2 and Y8 2 TAA are ... arrow). Y5 1 AMY2 and Y8 2 TAA are in orange. Other binding residues (W9 AMY2 , H92 AMY2 , T94 AMY2 , A9 5 AMY2 , Y1 30 AMY2 , A1 45 AMY2 , F180 AMY2 , K182 AMY2 , W206 AMY2 , S208...
Ngày tải lên: 31/03/2014, 08:20
Báo cáo y học: "TWEAK: a novel biomarker for lupus nephritis" pot
... injury has anti- inflammatory effects [5]. In the current paper by Schwartz and colleagues, TWEAK was assessed as a biomarker for LN in both cross-sectional and longitudinal studies. In the former, ... array of cytokines, chemokines and cell adhesion molecules. TWEAK plays a role in tissue inflammation, repair and regeneration in many diseases, including SLE [5]. In a...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: "miRTRAP, a computational method for the systematic identification of miRNAs from high throughput sequencing data" pptx
... and their miRNA partners in RNA silencing. Proc Natl Acad Sci USA 2008, 105:7964-7969. 33. Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai ... apparent false negative rate of approxi- mately 5% and a false discovery rate of approximately 19%. To systematically compare the miRTRAP and miRDeep methods, we tested the new Ciona libr...
Ngày tải lên: 09/08/2014, 20:21