Báo cáo y học: "Human genetics moves from clinic to bench - and back" ppsx
Báo cáo y học: "Human genetics moves from clinic to bench - and back" ppsx
... disorders.
High-throughput technology and data analysis
On the high-throughput front, a novel array-based whole-
genome genotyping assay that effectively enables unlimited
SNP genotyping from a single ... related to their selection to respond to
environmental stress. The cytochrome P450 isoenzymes
CYP2C19 and CYP2D6, for example, are involved in the
metabolism of many widely used...
Báo cáo y học: "Human genetics branches out in Barcelona" pdf
... with
cis-regulatory loci in 16% of the miRNAs studied by her
team, for example, miR-100 and miR-16. Association of
miRNA expression with trans-regulatory loci was found in
only 5% of the miRNAs analyzed, ... described that a low copy number of the CNV
spanning the gene for the low-affinity Fc receptor for IgG
(FCGR3B) is a risk factor for systemic lupus erythematosus
and other autoimmune...
Báo cáo y học: "Human articular chondrocytes express 15-lipoxygenase-1 and -2: potential role in osteoarthritis" pdf
... purposes)
(MMP-1, -8 , and -1 3), the gelatinases (MMP-2 and -9 ), the
stromelysins (MMP-3, -1 0, and -1 1), the matrilysins (MMP-7
and -2 6), and the membrane-bound-type MMPs (MMP-14, -
15, -1 6, -1 7, -2 4, and -2 5). ... 3
13-HODE and 15-HETE downregulate induction of MMP-1/MMP-13 protein synthesis by IL-1β, TNF-α and IL-1713-HODE and 15-...
Báo cáo y học: "Microbicides 2008 conference: From discovery to advocacy" ppsx
... microflora, pregnancy and
impact on body function due to systemic absorption or
inflammatory response. Symptoms and colposcopy do
not necessarily indicate safety and recent outcomes of tri-
als suggest ... policy and pro-
grammes to build the social and health platform for the
adolescents (10–19 years), youth (15–24 years), espe-
cially young girls [67]. Conventional "youth...
Báo cáo y học: "Inflammatory Signals shift from adipose to liver during high fat feeding and influence the development of steatohepatitis in mice" pot
... IL-6, IL-10, IFN-g and TGFb-1 genes are differentially upregulated in both adipose and liver tissues of HFC-fed mice. Expression
levels of IL-6, IL-10, IFN-g and TGFb-1 from chow (in black) and HFC ... GM-CSF, TNF-a,IL-12p7 0and
IL-1b in these HFC-mice. Serum amyloid A (SAA) levels
were variable at 6 and 16 weeks post-HFC but wer e sig-
nificantlyelevatedintheHFC-fedmiceat26weeks...
Báo cáo y học: "Inflammatory Signals shift from adipose to liver during high fat feeding and influence the development of steatohepatitis in mice" pptx
... GM-CSF, TNF-a,IL-12p7 0and
IL-1b in these HFC-mice. Serum amyloid A (SAA) levels
were variable at 6 and 16 weeks post-HFC but wer e sig-
nificantlyelevatedintheHFC-fedmiceat26weeks
post-HFC. IL-10 ... HFC-fed mice
A complex regulation of pro-inflammatory cytokine
genes was observed at different time points in both adi-
pose and liver tissues, underlying both disease-promoting
and compe...
Báo cáo y học: " Human herpesvirus-8 in northwestern China: epidemiology and characterization among blood donors" pdf
... were cen-
trifuged and stored at -8 0°C before HHV-8 serologic
testing.
Laboratory procedures
The coded serum specimens were tested for HHV-8 anti-
gens of ORF
73
,ORF
65
and K8.1 using enzyme-linked
immunosorbent ... 1995, 1:70 7-7 08.
3. Cesarman E, Chang Y, Moore PS, et al: Kaposi’s sarcoma-associated
herpesvirus-like DNA sequences in AIDS-related body-cavity-based
lymphomas. N E...
Báo cáo y học: "Understanding embryonic development: from screens to genes" pptx
... activity of the
G-protein regulators GPR-1 and GPR-2 (GPR1/2). CK1 func-
tions upstream of phosphatidylinositol-4-phosphate 5-kinase
(PPK-1), a protein that generates phosphatidylinositol diphos-
phate ... position
and orientation. chp-1 is also known to function in maintain-
ing the balance between anterior and posterior PAR
(partitioning-defective) proteins. CHP-1 normally localizes...
Báo cáo y học: "Inferring transcriptional modules from ChIP-chip, motif and microarray data" pptx
... ReMoDiscovery correlation threshold
GRAM mo du le
p-value cutoff
0.05
0.045
0.04
0.035
0.03
0.025
0.02
0.015
0.01
0.005
GRAM co re pr ofil e
p -value cu to ff
-3
-4
-5
-6
-7
-8
-9
-1 0
-1 1
-1 2
(a) ... ACE2_YPD,
FKH1_YPD, FKH2_H2O2Hi, FKH2_H2O2Lo, FKH2_YPD,
MBF1_YPD, MBP1_H2O2Hi, MBP1_H2O2Lo, MBP1_YPD,
MCM1_Alpha, MCM1_YPD, NDD1_YPD, RFX1_YPD,
RPN4_YPD, STB1_Y...
Báo cáo y học: "Health system weaknesses constrain access to PMTCT and maternal HIV services in South Africa: a qualitative enquiry" pptx
... manu-
ally. The type of indicators recorded - and the actual fig-
ures tallied - seemed to reflect only a portion of the
actual PMTCT and ART activity, and the data were
generally of poor quality. ... short-course zidovudine regimen to prevent mother -to-
child transmission of HIV-1 in West Africa. Journal of Acquired Immune
Deficiency Syndromes 2002, 16:63 1-6 41.
30. Co...