Báo cáo y học: "Genome-wide promoter extraction and analysis in human, mouse, and ra" potx
Báo cáo y học: " Induction of multiple matrix metalloproteinases in human dermal and synovial fibroblasts by Staphylococcus aureus: implications in the pathogenesis of septic arthritis and other soft tissue infections" pdf
... during S. aureus infections. Calander and colleagues
[29], using wild-type S. aureus strain 8325-4 and its mutants
lacking aureolysin, serine protease, and cysteine protease,
demonstrated in ... expression of
a 92-kD gelatinase (type V collagenase) by rheumatoid syno-
vial fibroblasts and its induction in normal human fibroblasts
by inflammatory cytokines. J Clin Invest 1991, 88:1...
Báo cáo y học: " Histone deacetylase inhibitors induce apoptosis in human eosinophils and neutrophils" docx
... G: Binding mode analysis of 3-(4-benzoyl-1-
methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide: a new synthetic
histone deacetylase inhibitor inducing histone hyperacetylation, growth
inhibition, and ... 3-(4-
toluoyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propena-
mide; ( MS-275): [N-(2-aminophenyl)-4-[N-(pyridine-3-
ylmethoxy-carbonyl)aminomethyl]benzamide]; (PDTC):
ammo nium pyrrolidinedithioc...
Báo cáo y học: "Genome-wide promoter extraction and analysis in human, mouse, and ra" potx
... extraction and analysis in human, mouse,
and rat
Zhenyu Xuan, Fang Zhao, Jinhua Wang, Gengxin Chen and
Michael Q Zhang
Address: Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY ... DNA
methylation).
Sensitivity and specificity of promoter prediction for CpG-island related and non-CpG-island related promoters in different gene setsFigure 3
Sensiti...
Báo cáo Y học: The role of arginine residues in substrate binding and catalysis by deacetoxycephalosporin C synthase potx
... of the a-aminoadipoyl- side-chain
of penicillin N (1), with arginines 74 and 75 apparently
playing a less important role in side-chain binding. Taken
together, the results of this and previous ... contains eight arginine residues within, or close
to, its active site that may be involved in catalysis. Arg258
has already been shown by structural and mutagenesis
studies to bind the 5-c...
Báo cáo y học: "How safe are the biologicals in treating asthma and rhinitis" doc
... Interleukin-13 Inhibition
Interleukin-4 (IL-4) and Interleukin-13 (IL-13) are
cytokines that play a role in allergic inflammation by
inducing Th2 responses. Interleukin-4Rα is the signaling
component ... Clinical features
Type α High cytokine & cytokine release syndrome Symptoms will depend on the cytokine or cytokine being targeted e.g., high levels of
INF-α may cause 'flu-like...
Báo cáo y học: "The Short Anxiety Screening Test in Greek: translation and validation" ppsx
... rendering it practical for
use in everyday practice. According to the developers,
the instrument can accurately and reliably identify
symptoms of anxiety in older people even, and espe-
cially, in ... R:
Screening for depression and anxiety disorders in primary care patients.
Depress Anxiety 2006, 24:455-60.
12. Peveler R, Kilkenny L, Kinmonth AL: Medically unexplained physical...
Báo cáo y học: "A psychophysiological investigation of laterality in human emotion elicited by pleasant and unpleasant film clips" pptx
... was
evidence of excessive activity (including a premature
eyeblink) during the baseline period. They were also
rejected if there was no evidence of an eyeblink having
been evoked by the startle probe. Altogether, ... baseline EMG
and latency to response onset, only the findings on
affective ratings and startle amplitude are reported here.
Although no significant interaction effect appeare...
Báo cáo y học: "Potential involvement of oxidative stress in cartilage senescence and development of osteoarthritis: oxidative stress induces chondrocyte telomere instability and downregulation of chondrocyte function" pptx
... stress induces telomere instability
and dysfunction in chondrocytes, subsequently resulting in
cartilage ageing and the development of OA through a
mechanism involving the acceleration of chondrocyte
senescence. ... prepared using standard histo-
logical procedures. For nitrotyrosine staining, the sections
were deparaffinized and hydrated, and then were immunos-
tained using antib...
Báo cáo y học: "Role of regulatory T cells in experimental arthritis and implications for clinical use" potx
... the paper by
Frey and colleagues represents only a minor blink of an eye in
the vast Treg literature, but Frey and colleagues introduce a
provocative ‘spin’ to their results as they question ... that in patients with IPEX
(immune dysregulation, polyendocrinopathy, enteropathy, X-
linked syndrome) [4] or scurfy mice [5] or by means of
depletion with anti-CD25 monoclonal antibodies in...
Báo cáo y học: " Imbalance of local bone metabolism in inflammatory arthritis and its reversal upon tumor necrosis factor blockade: direct analysis of bone turnover in murine arthritis" ppsx
... turnover, as typically
seen in juxta-articular and periarticular damage of inflamed
joints in RA. TNF is a proinflammatory cytokine of major impor-
tance in chronic inflammatory arthritis and also ... therapeutic standpoint the reversibility of the
pathophysiology of destructive arthritis is a key point of inter-
est. Since in this model TNF is not only responsible for inflam-
mat...