Báo cáo y học: "nomic mapping of RNA polymerase II reveals sites of co-transcriptional regulation in human cells" pot

... properly cited. Genomic mapping of RNA Polymerase II in human cells<p>Determination of the distribution on RNA Polymerase II within regions of the human genome identifies novel sites of transcription ... towards regions of active transcription and that determining sites of enrichment of RNA polymerase II is an indicator of transcription. Lev...

Ngày tải lên: 14/08/2014, 14:21

... expression of a group of procol- lagen hydroxylases. Eur J Biochem 2003, 270:4515-4522. 47. Takahashi Y, Takahashi S, Shiga Y, Yoshimi T, Miura T: Hypoxic induction of prolyl 4-hydroxylase alpha (I) in ... ven- tricular collagen type III and IV gene expression increases dur- ing early phases of endurance training in hypobaric hypoxic condition. Basic Res Cardiol 1997, 92:299-309...

Ngày tải lên: 09/08/2014, 10:20

... pro- duction of reactive oxygen metabolite in the antral mucosa in vivo [23]. Hp can induce the production of pro-inflammatory cytokines from gastric epithelial cells resulting in the increased ... analysis of 16184PolyC in mtDNA D-loop region. a: Sequence of 16184PolyC in mtDNA D-loop region of AGS cells, the section of black line is the normal sequence; b: Sequen...

Ngày tải lên: 25/10/2012, 11:18

... (N)-((S)-2-hydroxy-3-methyl- butyryl)-1-(L-alaninyl)-(S)-amino -3-methyl-2,3,4,5-tetra- hydro-1H-3-benzaze pin-2-one dihydrate (LY450139, semagacestat) was made in- house as describe d in Audia et ... tractability point of view with few compounds enter- ing clinical development, most likely due to the difficulties in achieving the combination of necessary enzyme inhibition with adequ...

Ngày tải lên: 10/08/2014, 10:20

... Researcher of CAMS & PUMC. Author details 1 State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union ... understanding of multiple myeloma. Journal of Hematology & Oncology 2010, 3:13. 4. Jiahuai Tan, Shundong Cang, Yuehua Ma, Petrillo LRichard, Delong Liu: Novel histone de...

Ngày tải lên: 10/08/2014, 21:23

... has proinflammatory as well as anti-inflammatory properties. Studies using knockout mice demonstrated that in innate immunity IL6 acts predominantly as an antiinflammatory cytokine, mainly by attenuating ... determined induction of c ytokine mRNA. Though we observed an increase in TNF-a, IL10 and IL6 mRNA in both cell types, the extent of TNF-a induction observed in IM was weak co...

Ngày tải lên: 12/08/2014, 11:22

... Alternatively the acquisition of Lys108 and Tyr110 by murine species might be required to maintain yet unknown physiological function of PAR while escaping deadly viruses. To further gain insight into this ... analysed by western blotting. QLH N-glycosylation site A Surface staining Intracellular staining C-HA HuPAR-2 N-HA HuPAR-2 Anti-CD71 B C CELL COUNTS Surface staining Intracellular...

Ngày tải lên: 13/08/2014, 05:22

... Cong* Address: Department of Pathophysiology, Beijing Institute of Radiation Medicine, Beijing, 100850, China Email: Xiaoling Yuan - xiaolingyuan@hotmail.com; Yajun Shan - shanyajun0207@sina.com; Zhenhu ... apoptosis induction of 3b protein might be a cell type specific. In order to further confirm the function of 3b protein in inducing cell apoptosis, a more definitive study usin...

Ngày tải lên: 19/06/2014, 08:20

... and Yuwen Cong* Address: Department of Pathophysiology, Beijing Institute of Radiation Medicine, Beijing, 100850, China Email: Xiaoling Yuan - xiaolingyuan@hotmail.com; Yajun Shan - shanyajun0207@sina.com; ... 154 amino acids [9]. Nucleolus localization of SARS-CoV 3b protein suggested that the expression of 3b protein may interfere with cell cycle regulation in transfected cells....

Ngày tải lên: 20/06/2014, 04:20

... subsite mapping. To completely map the binding region of a-amylases, we determined the number of subsites, located the position of the catalytic amino acids within the subsites and determined the binding ... barley a-amylase justify the ‘6 + 2 + (1) model’ prediction. Thebinding areaof barleya-amylase is composed ofsix glycone, two aglycone binding sites followed by a barrier subsite...

Ngày tải lên: 08/03/2014, 09:20