Báo cáo y học: "Analysis of the Macaca mulatta transcriptome and the sequence divergence between Macaca and human" ppt

... of polymorphic genes may act in concert in the pathogenesis of SLE, a concept that may be instrumental in the analysis of the genetics of SLE as well as providing hypotheses for pathways in the ... study. Analyses of disease phenotypes were beyond the scope of this study and will be addressed in future stud- ies. However, there were no apparent associations between...

Ngày tải lên: 09/08/2014, 01:24

... parotid gland of the SS patient, further analysis addressed the nature of these mutations. The R/S ratio of the nonproductive Vκ and Vλ repertoire could not be assessed individually because of the ... from the parotid gland and the peripheral blood of the patient, there was no significant difference in the R/S ratios. Comparison of the R/S ratio in the pe...

Ngày tải lên: 09/08/2014, 03:24

... organizational structure of these chromosomes, or they may merely reflect the still-incomplete state of the assembly and map of the genome sequence. A very high density is found in the unmapped scaffolds, contigs and ... chromosomes and 60% of these unmapped sequences are composed of repetitive DNA (Fig- ures 1 and 3). Completeness of the genome sequence and...

Ngày tải lên: 14/08/2014, 08:21

... yeast. GST-B4 inhibits the cytostatic activity of Vpr mutants and rescues cell growth To further investigate the correlation between the inhibi- tory effect of GST-B4 and its Vpr-binding ability, GST or GST-B4 ... characterized the B4 GST-di-W-containing peptide. GD participated in the design of the study and critically evaluated the manu- script. EAC participated...

Ngày tải lên: 13/08/2014, 13:20

... unrelated to cancer in the analysis. For many diseases, we have sufficiently good understanding of etiology and pathophysiology to be able to use them as 'landing lights' on the developmental surface. Conclusion The ... sets of genes or processes to the biology of aggregates on the order of the entire transcriptome is likely to be useful in establishing highl...

Ngày tải lên: 14/08/2014, 20:22

... analyzer was used to digitize the analog information contained in each pulse, to process and store the data in memory and finally to display the contents of the processed data in the form of ... characterized by the lack of isolated pockets of fat within its mass and this is demonstrated in these results by the lack of any adipose peak in the carcinoma diffr...

Ngày tải lên: 02/11/2012, 11:08

... quarantined in the Animal Research Center of Kanazawa University. All the animal procedure in this study complied with the standards set out in the Guide- line for the Care and Use of Laboratory Animals ... Ishiura Y, Abo M, Nakao S: Effects of suplatast tosilate, a new type of anti- allergic agent, on airway cough hypersensitivity induced by airway allergy in guinea-pigs...

Ngày tải lên: 13/08/2014, 08:20

... mulatta, one M. fascicularis, and one M. nemestrina. The breadth of the dataset provides an opportunity to conduct a preliminary analysis of the polymorphism frequency within M. mulatta and the ... monkeys and humans shared a common ancestor around 25 Mya, and the genomes of these organisms are highly conserved with human [33,35,38]. Furthermore, the biology of...

Ngày tải lên: 14/08/2014, 14:21

... of C4 in these mice, and that the loss of the major negative regulator of the classical complement pathway fails to impact disease severity, the use of the MRL mouse as a prototypical model of ... planned and performed the majority of the experiments and was primary author of the manuscript. KS performed the hemolytic assays and assisted in interpreting...

Ngày tải lên: 09/08/2014, 10:21

... design of the study, genotyped the sam- ples, and participated in the interpretation of the results and in writing the manuscript. MC participated in the statistical anal- ysis and in the interpretation ... the study and in the coordination of acquisition of clinical data and collection of samples, and supervised genotyping, statistical analysis, inter-...

Ngày tải lên: 09/08/2014, 14:20