Báo cáo y học: " Functional analysis of human and chimpanzee promoters" docx

... basis of the availability of an annotated transcription start site [28], the availability of human and chimpanzee DNA sequence of high quality, the possibility to place primers for amplification of ... observed among humans Human and chimpanzee promoter activity and mRNA expression in tissuesFigure 1 Human and chimpanzee promoter activity and mRNA expression in...

Ngày tải lên: 14/08/2014, 14:21

... particularly G21D, L87I, and P92L substantially reduced the ability of Mo to transactivate the LTR and without affecting NFkB activity (Table 3). Analysis of the subcellular location of mutant ... Sheehy N, Salemi M, VanDamme AM, Hall WW: Compar- ison of CREB- and NF-kappaB-mediated transactivation by human T lymphotropic virus type II (HTLV-2) and type I (HTLV-1) tax prot...

Ngày tải lên: 13/08/2014, 09:21

... incidence of disease transfer (Table 1), characterized by variable degrees of synovitis, soft-tissue inflammation, synovial hyperplasia, cartilage disruption characterized by pyknotic chondrocytes, and ... or onset of disease (data not shown). The ability of cells to adhere to the ECM is a critical deter- minant of cytoskeletal organization and cellular morphol- ogy [30], and...

Ngày tải lên: 09/08/2014, 01:21

... potentiated by enzymatic degradation of phospholipids [7,44]. The capacity of DM64 to inhibit the myotoxicity induced by myotoxins I (Asp49) and II (Lys49) from B. asper venom was analyzed in vivo and ... deglycosylation DM64 was chemically deglycosylated with anhydrous trifluoromethanesulfonic acid (TFMS) using the GlycoFree kit k-500 from Oxford GlycoSystems, USA and submitted to S...

Ngày tải lên: 21/02/2014, 01:21

... variants produced by p26-ND60 and p26-alpha were pr esent but recognized poorly by antip26 antibody. To determine if recognition of p26-ND60 and p26-alpha encoded polypeptides by antibody to p26 was ... chaperoning in vitro [66], and disassembly of active units from an oligomeric (storage) state of a-crystallin was proposed, upon structural analysis of aA-crystallin by site- d...

Ngày tải lên: 22/02/2014, 04:20

... puri®cation of CBG and allowed characterization in s ome detail, especially with respect to its glycone/aglycone speci®city a nd ability to catalyse the hydrolysis of dietary xenobiotic glycosides. ... 1989) Kinetic analysis of the interaction of alkyl glycosides with two human beta-glucosidases. Biochem. J. 262, 541±548. 11. Day, A.J. DuPont, M.S. & R idley, S. (1998) Degly...

Ngày tải lên: 08/03/2014, 16:20

... library (Genome Systems) by PCR. Each strand of the 5¢ flanking region of the Bsep gene was directly sequenced (Epidauros, Bernried, Germany) by automated sequencing. The sequence was analysed ... present the nucleotide sequence, as well as a systematic structural and functional analysis of the 5¢ flanking region of the Bsep gene. The 5¢ deletional analysis of the Bsep promote...

Ngày tải lên: 17/03/2014, 23:20

... induction of CXCL9 and CXCL10 could be a mechanism for lymphocyte accumu- lation around airways and blood vessels following lung injury by V 2 O 5 . Polypeptide growth factors have a variety of functions ... points tested. Microarray hybridizations and data analysis Human lung fibroblast RNA was isolated using RNeasy columns (Qiagen, Valencia, CA). RNA quality was verified by sp...

Ngày tải lên: 12/08/2014, 15:20

... cells Ingenuity pathway analysis shows a network of genes expressed in EB and BC data sets from the level II analysisFigure 4 Ingenuity pathway analysis shows a network of genes expressed in EB and BC ... Biology 2007, 8:R240 Ingenuity pathway analysis identified a network of genes expressed in EB and BC data sets associated with VEGFFigure 5 Ingenuity pathway analysis ide...

Ngày tải lên: 14/08/2014, 08:20

... Kaiserslautern, Germany; 2 Department of Evolutionary Microbiology, Faculty of Science, Catholic University of Nijmegen, the Netherlands The expression of mitochondrial and hydrogenosomal ADP/ATP ... dependency] of individual mitochondrial-type AACs in order to identify differences in the function of the various isoforms and to understand the repeated evolution of AAC isofor...

Ngày tải lên: 18/03/2014, 01:20