Báo cáo y học: "New names for old strains? Wolbachia wSim is actually wRi" ppt

... Biology 2005, Volume 6, Issue 7, Article 401 Iturbe-Ormaetxe et al. http://genomebiology.com/2005/6/7/401Genome Biology 2005, 6:401sequence similarity, fails to distinguishit from other hypotheses. ... slowly to be used for definitive strain identification; in somecases even the wRi and wMelsequences cannot be differentiated.The wsp gene is simply missing fromour wSim assembly, but is 99.9% ... looksmore like wAna than wSim. As should be apparent from this analysis,the assertion made by Iturbe-Ormaetxeet al. that wSim = wRi rests on alogical fallacy; that is, that if the bestunidirectional...

Báo cáo y học: "New tricks for old NODs" ppsx

... other biological systems: theRas family of GTPases is but one example.A persistent question and the genesis of significant debatewithin the innate immunity field is the mechanism by whichthese ... iimmmmuunniittyy aanndd aauuttooiimmmmuunniittyy Annu Rev Immunol2005, 2233::307-336.2. Kato H, Takeuchi O, Sato S, Yoneyama M, Yamamoto M, Matsui K,Uematsu S, Jung A, Kawai T, Ishii KJ, Yamaguchi ... tthhrroouugghhccrryyooppyyrriinn//NNaallpp33 Nature 2006, 444400::233-236.23. Mariathasan S, Weiss DS, Newton K, McBride J, O’Rourke K, Roose-Girma M, Lee WP, Weinrauch Y, Monack DM, Dixit VM: CCrryyooppyyrriinnaaccttiivvaatteess...

Báo cáo y học: ":New tricks for an old-favorite model" pps

... Saccharomyces cerevisiae as a model organism for studying metal metabolism. Iron is an essential micro-nutrient for almost all living organisms, serving as a co factor for a huge variety of cellular ... human disease studies and the use of yeast cells as factories.Yeast as model organism for aging studies and human diseaseDennis Thiele (Durham University, North Carolina, USA) uses Saccharomyces ... Proteome analysis revealed that amino acid metabolism and ribosome biogenesis are elevated whereas chaperones and TCA (tricarboxylic acid) cycle enzymes are decreased. Transcriptome analysis showed...

Báo cáo y học: "New hope for haplotype mapping" pptx

... necessary to type every DNA variant indi-vidually in an attempt to identify the functional polymor-phism responsible for a disease.Until recently, only a few studies provided limited informa-tion ... challenging issues.ConclusionIdentifying disease-related genetic polymorphisms incommon disease has never been easy. Recognising,however, that patterns of LD that were previously thoughtconfined ... over which a verysmall proportion (< 5%) of comparisons among informa-tive single nucleotide polymorphisms show strong evi-dence of historical recombination. This is an extremelyrigorous test...

Báo cáo y học: "New methodology for specific inhalation challenges with occupational agents" pdf

... validated by direct measurement instrumentFormaldehyde 0.65 mg/m30.63 0.63 0.08 0.87 0.36Formaldehyde 1.0 mg/m31.07 1.06 0.1 1.94 0.74Formaldehyde 1.7 mg/m31.43 1.43 0.04 1.58 1.31Isocyanates ... 0.66 0.05 0.7 0.56Formaldehyde 1.0 mg/m31.07 1.07 0.08 1.2 0.98Formaldehyde 1.7 mg/m31.69 1.65 0.08 1.82 1.64Isocyanates (1.6-HDI) 0.05 mg/m30.05 0.06 0.01 0.07 0.03Isocyanates (1.6-HDI) ... in a "realistic way" [5] for two hoursusing the same suspected occupational agent. For therealistic exposure to isocyanates, concentrations aremonitored and generally do not exceed...

Báo cáo y học: "New role for Agrin in T cells and its potential importance in immune system regulation" ppsx

... Center for Biotechnology InformationSpecies ISG15-Agrin linkage ChromosomeEutheria Homo sapiens Yes 1 Pan troglodytes Yes 1 Macaca mulatta Yes 1 Bos Taurus Yes 16 Canis lupus familiaris Yes ... of stimulation. Agrin is shown in its fully glycosylated (no activation) and modi ed (activation) forms. Also shown is a hypothetical receptor for Agrin expressed by the antigen presenting ... Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London EC1M6BQ, UKJury and Kabouridis Arthritis Research & Therapy 2010, 12:205 http://arthritis-research.com/content/12/2/205©...

Báo cáo y học: "New indications for the use of therapeutic hypothermia" doc

... injury due tovascular disruption, spinal cord injury and global anoxic injuryfollowing asphyxial cardiac arrest. In these conditions, anyCommentaryNew indications for the use of therapeutic hypothermiaStephen ... regarded hypothermia as quite hazardous, leadinginevitably to cardiac arrhythmias, sepsis, coagulopathy andelectrolyte abnormalities. Therefore, few centres appeared tobe interested in this novel ... fibrillation. This therapy is now endorsed by the International Liaison Committee on Resuscitation. The role of therapeutichypothermia in patients with anoxic neurological injury due to stroke,...

Báo cáo y học: "Gene profiling for defining targets for new therapeutics in autoimmune diseases" potx

... diseases usingmolecular profiling. I will focus on the gene expressionanalysis of T lymphocytes, the key players in severalinflammatory diseases, and on the microarray analysis ofbrain tissue ... variability.To exert their functions, type 1 and type 2 T lymphocyteshave to home into different sites. We reported anincreased expression of mRNA for fucosyltransferase VII,which codes for an enzyme ... dedicatedcomputational analysis tools for improved diagnosis andprognosis of cancer.Alizadeh et al. used a specially designed ‘lymphochip’ tocharacterize gene expression patterns of diffuse large B-celllymphoma,...

Báo cáo y học: "New insights into integrin signalling: implications for rheumatoid arthritis synovial fibroblasts" pptx

... transfer to synoviocytes andosteoclasts. J Clin Invest 1999, 104:137-146.14. Pap T, Franz JK, Hummel KM, Jeisy E, Gay RE, Gay S: Activationof synovial fibroblasts in rheumatoid arthritis: lack ... Gay S: Fibroblast biology. Roleof synovial fibroblasts in the pathogenesis of rheumatoidarthritis. Arthritis Res 2000, 2:361-367.7. Fassbender HG: Histomorphological basis of articular carti-lage ... 21:6289-6302.NoteThis article is based on papers highlighted by Faculty of1000 (http://www.facultyof1000.com/start.asp), a web-based literature awareness service. Faculty of 1000 evalu-ations available for...

Báo cáo y học: " Unique challenges for appropriate management of a 16-year-old girl with superior mesenteric artery syndrome as a result of anorexia nervosa: a case report" pptx

... removed,followed by transfer to the eating disorders unit, but thepatient and her family were not comfortable with thisplan. Ultimately, after many multidisciplinary meetingsinvolving nursing, discharge ... approximately 900 calories per day andexercising more vigorously: she was running 3.5 milesthree times a week and engaged in yoga for 1.5 hours a dayon non-running days and was also playing soccer. ... slowly in order to prevent refeeding syn-drome, seen in individuals who quickly transition from astate of malnourishment to feeding. Electrolytes shouldbe monitored closely, especially for hypophosphatemia,which...

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