Báo cáo y học: "The cyclophilins" pdf
Báo cáo y học: "The cyclophilins" pdf
... LocalizationSize (kDa) Protein CLD CLD CLD CLD CLD CLD CLD Cpr2 Cpr3 Cpr4 Cpr5 Cpr6 Cpr7 Cpr8 Cytoplasm and nucleus Secreted Mitochondria Vacuole ER Cytoplasm Cytoplasm Vacuole Mammalian ortholog 17 20 20 33 23 45 45 35 CypA CypB CypD CypC Cyp40 Cyp40 CypC SP This reference ... in v-Myb disrupt a cyclophilin-catalyzed negative regulatory mechanism. Mol Cell 1998, 1:203-211. This study shows...
Ngày tải lên: 14/08/2014, 14:21
Tài liệu Báo cáo Y học: The b-1,4-endogalactanase A gene from Aspergillus niger is specifically induced on arabinose and galacturonic acid and plays an important role in the degradation of pectic hairy regions pdf
... Genetics, Biochemistry and Ecology of Cellulose Degradation. (Ohmiya, K., Sakka, K., Karita, S., Hayashi, H., Kobayashi, Y. & Kimura, T., eds), pp. 134–143. Uni Publishers Co Ltd, Tokyo. 38. Schopplein, ... substrate specificity of the enzyme. The degradation of the polymer and subsequent oligosaccharide formation was analyzed by HPAEC and MALDI-TOF MS. HPAEC analysis demon- strated that...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: The structures of the lipooligosaccharide and capsule polysaccharide of Campylobacter jejuni genome sequenced strain NCTC 11168 pdf
... Hisatsune,K.,Kondo,S.,Isshiki ,Y. ,Iguchi,T.&Haishima ,Y. (1993) Occurrence of 2-O-methyl-N-(3-deoxy- L -glycero-tetronyl)- D -perosamine (4-amino-4,6-dideoxy- D -manno-pyranose) in lipo- polysaccharide from ... aerotolerant Campylobacter jejuni O:2 lipopoly- saccharide. Carbohydr. Res. 330, 223–229. 50. Yuki, N., Yoshino, H., Sato, S. & Miyatake, T. (1990) Acute axonal polyneuropath...
Ngày tải lên: 21/02/2014, 01:21
Báo cáo Y học: The role of the second binding loop of the cysteine protease inhibitor, cystatin A (stefin A), in stabilizing complexes with target proteases is exerted predominantly by Leu73 pdf
... of cystatin B with cysteine proteases [37]. The sequence of the second binding loop of the related family 1 cystatin, cystatin A, differs appreciably from that of cystatin B. Most notably, cystatin ... to 5% substrate hydrolysis. Inhibitor concentrations were at least 10-fold higher than enzyme concentrations. The inhibition of the enzymes by L73G-cystatin A was analysed at cystatin concentra...
Ngày tải lên: 17/03/2014, 10:20
Báo cáo Y học: The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase pdf
... phenylacetic acid; PAAM, phenylacetamide; PAAOM, phenylacetic acid methyl ester; PG, phe- nylglycine; (H)PGA, (p-hydroxy)- D -phenylglycine amide; (H)PGM, (p-hydroxy)- D -phenylglycine methyl ... methyl ester or the amide as acyl donor. It appeared that 6-APA and 7-ADCA were able to efficiently deacylate the phenylglycyl- and p-hydroxyphe- nylglycyl-enzyme of bF24A, as indicated by, respective...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo Y học: The reactivity of a-hydroxyhaem and verdohaem bound to haem oxygenase-1 to dioxygen and sodium dithionite pdf
... B.M. (1999) Hydroperoxy-heme oxygenase generated by cryoreduction catalyzes the formation of a-meso-hydroxyheme as detected by EPR and ENDOR. J. Am. Chem. Soc. 121, 10656–10657. 17. Liu, Y. , Lightning, ... ferrous complex was mainly formed through reduction of free a-hydroxyhaem by dithionite followed by its direct binding to the enzyme, rather than by reduction of the enzyme-bound ferric a...
Ngày tải lên: 23/03/2014, 21:20
Báo cáo Y học: The effect of amino-acid substitutions I112P, D147E and K152N in CYP11B2 on the catalytic activities of the enzyme pdf
... Determination of 11b-hydroxylase capacity of CYP11B2 mutants in relation to the wild-type enzyme, when incubated with 11-deoxycortisol. The 11b-hydroxylation of 11-deoxycortisol catalysed by the mutated ... endocrine diseases, Fig.3.Assessmentof11b-h ydroxylase a ctivity and determination of 11b-hydroxylase capacity. (A)Assessmentof11b-hydroxylase activity of CYP11B2 var iants e xpressed i n...
Ngày tải lên: 24/03/2014, 03:21
Báo cáo Y học: The cold-active lipase of Pseudomonas fragi Heterologous expression, biochemical characterization and molecular modeling pdf
... hydrolysis assay, rPFL displayed highest activity at 29 °C and pH 8.0, in good agreement with results reported for the wild type enzyme [30]. Interestingly, the enzyme lost most of its activity at ... hypothesis that PFL might be secreted by a signal peptide-independent pathway and calls for further investigation on this subject. Enzyme activity and specificity In the standard tricaprylin hydr...
Ngày tải lên: 24/03/2014, 04:21
Báo cáo Y học: The cytoplasmic C-terminus of the sulfonylurea receptor is important for KATP channel function but is not key for complex assembly or trafficking pdf
... hyperinsulinaemic hypoglycaemia of infancy is an hereditary disease char- acterized by inappropriately high levels of insulin release and hypoglycaemia in children at birth. It is hypothesized that ... Bleeds were assayed for activity using an antibody capture assay [16] and bleeds showing reactivity were affinity purified. Kir6.2 antisera to the C-terminus of the channel and myc hybridoma cell...
Ngày tải lên: 31/03/2014, 08:20