Báo cáo y học: "Large-scale 13C-flux analysis reveals mechanistic principles of metabolic network robustness to null mutations in yeast" pptx

... (Figure 5). Inactivation of the mitochondrial pyruvate dehydrogenase complex in the pda1 mutant was bypassed by the import of cytosolic acetyl-CoA into the mitochondria. Inactivation of the oxidative ... ratio analysis The recorded MS spectra include the distribution of mass iso- topomers in 1-5 fragments of alanine, aspartate, glutamate, glycine, isoleucine, leucine, phenylal...

Ngày tải lên: 14/08/2014, 14:21

... cir- cadian rhythm of resistance to extreme temperatures and changes in fatty acid composition in cotton seedlings. Plant Physiol 1993, 101:31-36. 81. Foyer CH, Noctor G: Oxygen processing in photosynthesis: regulation ... circadian phases of peak transcript abundance of ethylene signaling and ethylene responsive genes. Interestingly, two key ethyl- ene signaling components, nam...

Ngày tải lên: 14/08/2014, 20:22

... binding affinity of a site to REST without requiring strict matching of each base to the NRSE consen- sus. To reduce false positives, we rely on comparative sequence analysis to identify only ... (3'UTRs) of the messages. Many of the characterized miRNAs are involved in developmental regulation, including the timing and neuronal asymmetry in worm; growth control and...

Ngày tải lên: 14/08/2014, 17:22

... that the potency of cyclo 128 OP was increased by a factor of three and its efficacy by a factor of 1.4 compared to its linear counterpart in eliciting [Ca 21 ] i rise in rat astrocytes. As the ... amide proton frequency. Two glycine-type remote peaks were clearly observed instead of one expected, suggesting the existence of two spectroscopically distinct molecular conformers....

Ngày tải lên: 24/03/2014, 04:21

... Simons, K. (1999) Clusters of glycolipid and glycosylphosphatidyl-inositol-anchored proteins in lymphoid cells: accumulation of actin regulated by local tyrosine phosphorylation. Eur. J. Immunol. ... stimulated tyrosine-phosphorylation of STATs IL-2 induced tyrosine phosphorylation of STAT3 (and STAT5) was followed by flow cytometry as described previ- ously for STAT1 [32]. Brie y, c...

Ngày tải lên: 17/03/2014, 23:20

... this understanding is gained, H-tunneling can then be used as a tool for (a) increasing the catalytic efficiency of enzymes in the biotechnology industry (by enhancing the coupling of dynamics to the ... nss4@le.ac.uk Abbreviations:TST,transitionstatetheory;TTQ,tryptophantrypto- phylquinone; MADH, methylamine dehydrogenase; AADH, aroma- tic amine dehydrogenase; TMADH, trimethylamine de...

Ngày tải lên: 31/03/2014, 23:20

... is induced by AGE, can contribute to the inflammatory cycle by the induction of proinflammatory cytokines, via the nuclear factor-κB pathway [21]. No studies have yet examined RAGE expression in ... Nε-(car- boxymethly)lysine (50 mg/ml) inhibited the binding of poly- clonal anti-IgG-AGE antibodies to IgG-AGE by 40% but did not inhibit RF binding to IgG. Lysine at the same con- cen...

Ngày tải lên: 09/08/2014, 01:21

... Vanderbilt University, Nashville, TN; Yusuf Yazici, NYU Hospital for Joint Diseases, New York, NY; Martin Bergman, Taylor Hospital, Ridley Park, PA; Christopher Swearingen, Medical University of South Carolina, ... Maria Majdan, Medical Uni- versity of Lublin, Lublin; Wojciech Romanowski, Poznan Rheu- matology Center in Srem, Srem; Witold Tlustochowicz, Military Institute of Medicine,...

Ngày tải lên: 09/08/2014, 01:22

... contributed to study design, acquisition of data, analysis and interpretation of data, and sta- tistical analysis. M-JB and FA contributed to acquisition of data and to analysis and interpretation of ... evidence of OA of the affected knee on a radio- graph obtained within 6 months of the outset of the study. Finally, patients had to have a minimum joint space wid...

Ngày tải lên: 09/08/2014, 10:20

... 40620 Jyväskylä, Finland 6 Gazi University, Department of Physical Medicine and Rehabilitation, Division of Rheumatology, 06530 Ankara, Turkey 7 Rheumatology Department, Institute of Rheumatology ... Vanderbilt University, Nashville, TN; Yusuf Yazici, NYU Hospital for Joint Diseases, New York, NY; Martin Bergman, Taylor Hospital, Ridley Park, PA; Christopher Swearingen, Medical Universi...

Ngày tải lên: 09/08/2014, 13:22