Báo cáo y học: "Mechanisms of aging in senescence-accelerated mice" pptx

... strains and there is a growing body of evi- dence supporting the importance of chronic inflammation in mammalian aging [47-49]. Intriguingly, such an immune/ inflammatory response may play a ... differences in transcriptional aging between strains (Figure 2). Unexpectedly, each strain showed a remarkably unique pro- file of aging. In the aging hippocampus, only a single gen...

Ngày tải lên: 14/08/2014, 14:21

... Thus, serine/threonine kinases and tyrosine kinases have been characterized as distinct types of kinases involved in receptor signalling. Tyrosine kinases are further differentiated for their intrinsic ... 2006 ␤-Arrestin Function in Regulating Exocytosis The family of scaffolding proteins, ␤-arrestins, may be required for activating signalling pathways leading to exocytosis of prim...

Ngày tải lên: 08/08/2014, 21:20

... hypertrophic chondrocytes and appears to play a role in reducing some BMP signals in the replacement of hypertrophic chondro- cytes by bone. A reduction in these endogenous noggin levels in noggin haplo-insufficient ... mediators of new bone formation such as BMP2 are induced in different cell types (including synovial fibroblasts and cartilage cells) by pro-inflammatory cytokin...

Ngày tải lên: 09/08/2014, 13:22

... activation of other muscles in the surrounding area. (which would be greater). Furthermore, as AMI is caused by activity in multiple inhibitory pathways [57], the influence of γ-loop dysfunction may ... completely prevented by a given inhibitory input, others will only be partially inhibited and are still able to depolarise [58]. However, when two (or more) forms of inhibitory/d...

Ngày tải lên: 12/08/2014, 18:20

... expression by the infected B lym- phocytes. As revealed by a series of relatively specific inhibitors, the metabolic pathways involved in viral expression include protein kinase C, calmodulin and intracellular ... (namely, gamma-glutamyl-L- cysteinyl-glycine [GSH]) by using ethacrynic acid or 1-pyr- rolidinecarbodithioic acid specifically counters the inhibi- tion of spontaneous apoptos...

Ngày tải lên: 13/08/2014, 09:20

... con- taining multivitamins (NP1; the pH value is 5.6 and the osmotic pressure ratio to physiological saline [OPR] is approximately 4), all of the standard strains and the clinical isolates of ... difference in the mean values of the 3 strains. All 4 strains of B. cereus did not increase in NP1 for 48 hours (Figure 1c), and there was a significant decrease (p<0.01) in t...

Ngày tải lên: 26/10/2012, 09:39

... demonstrated an increase in Physical Component Summary of >6 points in two-thirds of patients and an increase in Mental Component Summary score of >8 points in two-thirds of patients. ... quality of life (QoL) incorporates these dimensions and can be defined as “an individual’s perception of their position in life, and in the context of the culture and v...

Ngày tải lên: 03/11/2012, 10:52

Ngày tải lên: 03/11/2012, 11:01

... between Cyt f and plastocyanin and/or plasto- cyanin and photosystem I, and subsequently the nature of the interactions in the two lineages (hydrophobic in cyanobacteria, electrostatic in chloroplasts) ... thermodynamic analysis by laser-flash absorption spectroscopy of photosystem I reduction by plastocyanin and cytochrome c 6 in Anabaena PCC 7119, Synechocystis PCC 6803, and spin...

Ngày tải lên: 21/02/2014, 01:21

... these proteins can be activated independently, suggesting that each link is func- tional [5–7]. In addition, in megakaryocytic cell lines and in primary megakaryocytes, the precursor of platelets, ... protein con taining the RAS-b inding domain o f RAF. Precipi- tated proteins were resolved by 12.5% SDS/PAGE and analysed by Western blotting using an anti-RAS Ig (top). Proteins of wh...

Ngày tải lên: 08/03/2014, 16:20