Báo cáo y học: "Histone modifications: from genome-wide maps

Báo cáo y học: "Histone modifications: from genome-wide maps to functional insights" ppsx

... histone modifications. Genome-wide functional analysis of histone modifications Unraveling the role of histone modifications can be greatly facilitated by genome-wide analysis of histone-modifying enzymes. ... Another study employed expression profiling of yeast strains in which lysines on histone H4 were systematically mutated to arginine (which mimics unacetylated lysine) [21]. Mut...

Ngày tải lên : 14/08/2014, 14:21

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Báo cáo y học: "The shunt from the cyclooxygenase to lipoxygenase pathway in human osteoarthritic subchondral osteoblasts is linked with a variable expression of the 5-lipoxygenase-activating protein" doc

... 1,25-Dihydroxyvitamin D 3 pretreatment limits prostaglandin biosynthesis by cytokine-stimulated adult human osteoblast-like cells. J Cell Biochem 1998, 68:237-246. 61. Suzuki A, Tokuda H, Kotoyori ... from Cayman Chemicals (Ann Arbor, MI, USA) for PGE 2 (specificity 100%, sensitivity 7.8 pg/ml), from R&D Systems (Minneapolis, MN, USA) for IL-10 and from Medical and Bio- logical Lab...

Ngày tải lên : 09/08/2014, 08:23

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Báo cáo y học: "Histone tales: echoes from the past, prospects for the future" ppt

... methylation. is prompted the authors [5] to investigate whether, alternatively, histone modiﬁcations could bridge the dauer state to a lasting transcriptional record. Genome-wide analysis by ... developmental trajectories in response to environmental stimuli. Although these chromatin marks seem to be central to the formation of a kind of rudimentary memory, they do not suﬃ...

Ngày tải lên : 09/08/2014, 20:21

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Báo cáo y học: "Does switching from oral extended-release methylphenidate to the methylphenidate transdermal system affect health-related quality-of-life and medication satisfaction for children with attention-deficit/hyperactivity disorder&

... do you worry about your child missing a dose of ADHD medication at school or when you are not around? • How bothered are you by having to monitor your child's ADHD medication everyday? ... months, have you, your spouse or part- ner missed days from work due to problems with your child's ADHD? During the past 6 months, has your child required any hours of extra tutoring, nursi...

Ngày tải lên : 25/10/2012, 10:06

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Tài liệu Báo cáo Y học: Binding of gelsolin domain 2 to actin An actin interface distinct from that of gelsolin domain 1 and from ADF/coﬁlin pptx

... directed to the actin sequences were selectively purified by affinity chromato- graphy [23]. Anti-IgG antibodies labelled with alkaline phosphatase were from Sigma. Synthetic peptides derived from ... collected by centrifugation. The bacteria were lysed by repeated freeze–thaw cycles with sonication. Supernatant containing the S2 protein was applied to a DE52 column and purified further...

Ngày tải lên : 22/02/2014, 07:20

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Báo cáo Y học: Stepwise adaptations of citrate synthase to survival at life’s extremes From psychrophile to hyperthermophile pot

... citrate synthase from diﬀer- ent organisms to a total of ﬁve that span the temperature range over which life exists (from psychrophile to hyperthermophile). Detailed structural analysis has ... our analysis we have chosen the enzyme citrate synthase (CS) (EC 4.1.3.7), which catalyses the condensa- tion of oxaloacetate and acetyl-CoA to form citrate and CoA. The enzyme from psychr...

Ngày tải lên : 23/03/2014, 21:20

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Báo cáo Y học: Cytochrome c from a thermophilic bacterium has provided insights into the mechanisms of protein maturation, folding, and stability potx

... cytochrome c biogenesis. Genes required for cytochrome c biogenesis in bacteria Cytochrome c heme lyase has been identiﬁed as the enzyme responsible for heme attachment to the mitochondrial cytochrome ... Yamazaki, K., Kyogoku, Y. & Kobayashi, Y. (1998) Solution structure of thermostable cytochrome c-552 from Hydrogenobacter thermophilus determined by 1 H-NMR spectroscopy. Biochem...

Ngày tải lên : 24/03/2014, 03:21

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Báo cáo Y học: Pyruvate decarboxylase from Kluyveromyces lactis An enzyme with an extraordinary substrate activation behaviour pptx

... decarboxylase from brewer’s yeast; KlPDC, pyruvate decarboxylase from Kluyveromyces lactis; PsPDC, pyruvate decarboxylase from Pisum sativum;ScPDC, pyruvate decarboxylase from Saccharomyces cerevisiae;ZmPDC, pyruvate ... of the yeast Kluyveromyces lactis one gene was found to code for PDC [4]. Its nucleotide sequence has 85% identity to PDC1 from Saccharomyces cerevisiae. All am...

Ngày tải lên : 24/03/2014, 04:21

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Báo cáo y học: " Psoriatic arthritis: from pathogenesis to therapy" pdf

... spondyloarthropathy samples (both P = 0.001). The authors concluded that the synovial histopathology of PsA resembles that of other spondyloarthropathy subtypes and, like spondyloarthropathy, can ... the inflammatory joint fluid and in the synovium. Lymphocyte phenotypic subpopulations can be readily isolated from the joint fluid by fluorescence activated cell sorting techniques. By isolati...

Ngày tải lên : 09/08/2014, 01:22

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Báo cáo y học: "Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption" ppt

... 8:707-717. 32. Nishida K, Komiyama T, Miyazawa S, Shen ZN, Furumatsu T, Doi H, Yoshida A, Yamana J, Yamamura M, Ninomiya Y, et al.: Histone deacetylase inhibitor suppression of autoantibody-mediated arthritis ... histone deacetylase inhibitor suberoylanilide hydroxamic acid exhibits antiinflammatory properties via suppression of cytokines. Proc Natl Acad Sci USA 2002, 99:2995-3000. 57. Reddy...

Ngày tải lên : 09/08/2014, 06:22

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