... formation of 16a-hydroxyprogesterone. Both expressed enzymes had no lyase activity towards PROG or 17-OHPROG. Understanding of the complexity of hydroxylase and lyase activity of CYP17 by way of primary ... Scotland, UK Human cytochrome P450 17a-hydroxylase (CYP17) cata- lyses not only the 17a-hydroxlation of pregnenolone and progesterone and the C17,20-side...
Ngày tải lên: 08/03/2014, 09:20
... reported for agmatine [7]. As a w hole, agmatine oxidation by P. sativum copper amine oxidase may represent a new biocatalytic route for the synthesis of N-amidino-2-hydroxypyrrolidine, possibly representing ... to L -citrulline (at pH 7.5 and 37.0 °C) and of the trypsin catalyzed hydrolysis of N-a-benzoyl- L -arginine p-nitroanilide (at pH 6.8 and 21.0 °C) by N-...
Ngày tải lên: 17/03/2014, 23:20
Báo cáo y học: "Fluvoxamine for blonanserin-associated akathisia in patients with schizophrenia: report of five cases." pps
... first report demonstrating that fluvoxamine is rapidly effective in the treatment of blonanserin-induced akathisia in patients with schizo- phrenia. Very recently, we reported that fluvoxamine ... proportion of patients fail to respond to treatment. In contrast, understanding of the pathophysiology of akathisia remains limited. Given the clinical profile of akathi...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: " From antibody insult to fibrosis in neonatal lupus – the heart of the matter" pps
... autoimmunity offers an exceptional opportunity to examine the effector Commentary From antibody insult to fibrosis in neonatal lupus – the heart of the matter Jill P Buyon and Robert M Clancy Department ... sections from several cases of CHB/myocarditis with varying degrees of pathology parallel the results obtained exploiting in vitro coculturing sys...
Ngày tải lên: 09/08/2014, 01:22
Báo cáo y học: "Higher susceptibility to Fas ligand induced apoptosis and altered α modulation of cell death by tumor necrosis factor-α in periarticular tenocytes from patients with knee joint osteoarthritis" ppt
... article Higher susceptibility to Fas ligand induced apoptosis and altered modulation of cell death by tumor necrosis factor- α in periarticular tenocytes from patients with knee joint osteoarthritis Andreas ... receptor I were measured using ELISA. Apoptosis was induced with recombinant human Fas ligand and measured by a histone fra...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Patients, their doctors, nonsteroidal anti-inflammatory drugs and the perception of risk" docx
... patients from the use of a given therapy, on the other hand, even very rare serious events may play a role in decision-making by patients, by their health care providers and by regulatory authorities. ... risks of chronic NSAID use on the gastrointestinal tract and blood pressure. Despite the current Commentary Patients, their doctors, nonsteroidal anti-inflammatory...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Cell signalling in macrophages, the principal innate immune effector cells of rheumatoid arthritis" pps
... the pathogenesis of RA and other inflammatory diseases, a great deal of interest exists in understanding the molecular basis of the signalling pathways induced by these receptors, with the hope of identifying ... adaptive immune systems in the pathology of the disease. The success of anti-tumour necrosis factor-α indicates the importance of pro-inflammato...
Ngày tải lên: 09/08/2014, 10:23
Báo cáo y học: "Decreased GABAB receptor function in the cerebellum and brain stem of hypoxic neonatal rats: Role of glucose, oxygen and epinephrine resuscitation" pot
... Access Decreased GABA B receptor function in the cerebellum and brain stem of hypoxic neonatal rats: Role of glucose, oxygen and epinephrine resuscitation Thoppil R Anju, Sadanandan Jayanarayanan and Cheramadatikudiyil ... GABA B receptor function in the cerebellum and brain stem of hypoxic neonatal rats: Role of glucose, ox...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "Asháninka medicinal plants: a case study from the native community of Bajo Quimiriki, Junín, Peru." doc
... Inga sp. Maranthaceae: Calathea sp. Onagraceae: Ludwigia peploides Headache 15% Anacardiaceae: Tapirira guianensis Araceae: Anthurium dombeyanum Asteraceae: Mikania micrantha Campanulaceae: Centropogon ... Nicotiana tabacum, Solanum americanum, Solanum mammosum, Solanum spp. Urticaceae: Urera cf. Baccifera Verbenaceae: Lantana camara Intestinal parasites 15% Amaranthaceae: Iresine diffusa Ann...
Ngày tải lên: 10/08/2014, 09:21
Báo cáo y học: "Augmented low-Dye tape alters foot mobility and neuromotor control of gait in individuals with and without exercise related leg pain" docx
... pattern s, foot posture and foot mobility. These effects occur in individuals with and without pain, and are dissipated up the kinetic chain. ALD tape should be considered in the management of individuals ... for exercise- related lower leg pain. Gait Posture 2006, 23:91-98. 5. Reinking MF, Hayes AM: Intrinsic factors associated with exercise- related l...
Ngày tải lên: 10/08/2014, 21:24
Báo cáo y học: "Diabetic fetopathy associated with bilateral adrenal hyperplasia and ambiguous genitalia: a case report" ppsx
... fetopathy associated with bilateral adrenal hyperplasia and ambiguous genitalia: a case report Patou Tantbirojn* 1 , Mana Taweevisit 2 , Suchila Sritippayawan 1 and Boonchai Uerpairojkit 1 Address: ... an absent nose, absent bilateral ears, median cleft lip and palate, preaxial polydactyly of the right hand, accessory spleens, single umbilical artery, markedly en...
Ngày tải lên: 11/08/2014, 21:22
Báo cáo y học: " Glutathione S-transferase omega in the lung and sputum supernatants of COPD patients" potx
... in the metabolism and maintenance of GSH levels in intact cells [20,22]. Since GSH is one of the major antioxidants of the airways, it can be hypothesized that GSTO may participate in the maintenance ... range of normal tissues, particularly in the liver but also in the lung (three specimens); in the lung GSTO1-1 could be found only in macrophages. T...
Ngày tải lên: 12/08/2014, 15:20
Báo cáo y học: " CpG oligonucleotide activates Toll-like receptor 9 and causes lung inflammation in vivo" ppsx
... cytokines in the lung and plasma and finally lung inflammation. These effects were absent in TLR9-D mice. We propose the TLR9 signalling cascade as an additional pathway to induce pul- monary inflammation. Lung ... 0,05). Discussion Acute lung injury represents acute hypoxemic respiratory failure and is associated with pulmonary and non-pulmo- nary risk factors. Interest...
Ngày tải lên: 12/08/2014, 15:21
Báo cáo y học: " Bench-to-bedside review: Toll-like receptors and their role in septic shock" pps
... This expanding IL-1R1-like family includes murine and human proteins, Drosophila (fruit fly) proteins, and a plant (tobacco) protein [7,8]. In Drosophila, Toll is involved in the rapid and transient ... regions of Toll and 18W contain multiple leucine-rich repeats and carboxyl-terminal cysteine-rich domains [12]. Drosophila Toll signaling pathway Current understanding of the Tol...
Ngày tải lên: 12/08/2014, 18:21
Báo cáo y học: "ilot Anopheles gambiae full-length cDNA study: sequencing and initial characterization of 35,575 clones" pps
... Access 2005Gomezet al.Volume 6, Issue 4, Article R39 Method Pilot Anopheles gambiae full-length cDNA study: sequencing and initial characterization of 35,575 clones Shawn M Gomez Ô * , Karin Eiglmeier Ô * , ... properly cited. Over 35,000 Anopheles gambiae full-length cDNA clones<p>A preliminary analysis of over 35,000 clones from a full-length enriched...
Ngày tải lên: 14/08/2014, 14:21