Báo cáo y học: "A novel scheme to assess factors involved in the reproducibility of DNA-microarray data" pdf

... used to obtain DNA-microarray data of improved quality. A novel scheme to assess factors involved in the reproducibility of DNA-microarray data Running title: a novel scheme to assess ... data quality. In order to assess the reproducibility of- and factors involved in DNA-microarray data produced in our laboratory during tr...

Ngày tải lên: 14/08/2014, 14:21

... summarized by their motif name (in bold), by their consensus sequence, if known, as described in the original article, by the sequence of the motif instance in our search, by the positions of the motif ... article, by the sequence of the motif instance in our search, by the positions of the motif instance relative to the consensus sequence of the ent...

Ngày tải lên: 14/08/2014, 16:20

... stoichiometric binding of protease inhibitors to the catalytic site of the activated forms of the enzymes. In the present work, we have measured by flow cytometry the net proteolytic activity ... surprising since the levels of MMP-9 in SF have been shown to vary according to several factors, such as the dis- ease state, the local concentration of inflammat...

Ngày tải lên: 09/08/2014, 08:22

... shown in Fig 1C, phages displaying the DSP peptide specifically bind to a synthetic biotinylated TMG peptide (Fig. 1C, TMG). Conversely, phages displaying the TMG peptide bind to a synthetic biotinylated ... chaperon- ing peptides into the antigen processing pathway of iDC, may also trigger IFN-γ production in a similar way to that of LPS [46-49]. These findings are in a...

Ngày tải lên: 11/08/2014, 10:23

... clinic complaining of left calf pain. He visited our clinic 10 days after the sudden onset of pain at the left medial aspect of the posterior calf during rigorous steep mountain climbing. In ... 90 degrees. The transducer was now pointing upwards to examine the calf muscles. (B) Longitudinal US image examined approximately 17 days after the initial injury revealed a well...

Ngày tải lên: 11/08/2014, 17:21

... fixing the value of z within the restrictions imposed by the dimensions of the inter- cellular channel. We f ixed the value of the height of the superimposed solutions to be at the middle of the intercellular ... whereas the ver- tical boundary conditions are considered to be of the n o-flux type, to represent the symmetry of the linear flow. We a...

Ngày tải lên: 13/08/2014, 16:20

... receiving this message by setting their cluster ID temporarily to be the ID of the COV as shown in line 3. Vehicles start calculating their suitability to become a CH as shown in line 4. Then, the ... only r-stable neighbors of the winner (since the cluster boundary is defined by r), which belong to the Γ(t) of the COV change their state to a CM and change their...

Ngày tải lên: 20/06/2014, 20:20

... thrombin–FXI interaction. The only assumption made was that the value of the asymptotic parameter V ¥ corresponds to the velocity of the substrate hydrolysis by the FXIa concentration equal to the ... activation loop at the N-terminus of the catalytic domain, are notable. In the zymogen FXI, Ile371 is exposed to the solvent, while in the activated FXI i...

Ngày tải lên: 23/03/2014, 07:20

... first cloning step into a shuttle plasmid containing a promoter for the expression of the transgene. After selection of recombinants, the plasmid DNA of each clone has to be transferred into an other ... reducing considerably the time of selection and, of course, production of the corresponding vectors. Using this vector, we produced recombinant adenoviruses, each givi...

Ngày tải lên: 20/06/2014, 01:20

... prekallikrein (PK) to the surface of endothelial cells and leukocytes [7], gen- erates the enzyme kallikrein. Kallikrein in turn cleaves HK to yield the inflammatory mediators bradykinin (BK) and ... was obtained from the left atrium as the heart beat. The sample of 3 to 5 ml was obtained by slow vacuum (to prevent hemolysis) within a minute (to prevent clotting in...

Ngày tải lên: 09/08/2014, 06:22