Báo cáo y học: "Making systems biology work in the 21st century" pot

... centers for systems biology over the next two years, investing £6 million in each. It was in the hope of answering them that a one-day meeting exploring the nature of systems biology and its potential ... Genome Biology 2005, 6:317 comment reviews reports deposited research interactions information refereed research Meeting report Making systems biology work in th...

Ngày tải lên: 14/08/2014, 14:21

... nucleotide polymorphisms (SNPs) in wheat is compli- cated, however, by the triplication of genetic information in the hexaploid genome, resulting in the need to distinguish inter-genome polymorphisms ... during early grain development whereas the homoeologs are expressed exclusively in leaf tissue [25]. The mechanisms that control chromosome pairing in poly- ploids are par...

Ngày tải lên: 09/08/2014, 20:20

... (m/z) % intensity% intensity % intensity % intensity % intensity% intensity % intensity % intensity (cii) (dii) D. virilis D. mojavensis D. pseudoobscura D. sechellia (bii) Genome Biology 2008, ... (m/z) % intensity% intensity % intensity % intensity % intensity% intensity % intensity % intensity D. virilis D. mojavensis D. pseudoobscura D. sechellia (dii) (cii) (bii) (aii) Genome Biology...

Ngày tải lên: 14/08/2014, 20:22

... guidelines are not yet in general use by the scientific community. Harmonization of the different guidelines to enable the integration of multi- omics data, a prerequisite for systems biology, also ... identified in this study are currently being screened for mutations in patients with cardiomyopathy with the aim of improving diagnosis. Alexander Marmé (University of Tübingen...

Ngày tải lên: 14/08/2014, 20:22

... international researchers in the interacting disciplines of synthetic biology, systems biology and bio- informatics. This conference was largely student-run, and as well as the formal talks included ... (Univer- sity of Oxford, UK): that synthetic biology may pose risks in terms of malevolent use, and that the use of synthetic biology might undermine the moral status of l...

Ngày tải lên: 14/08/2014, 21:20

... leaves developing at low temperatures. Increasing cytoplasmic volume accompanies increased activities of enzymes in the Calvin cycle and in the sucrose-biosyn- thesis pathway. Plant Physiol 119, ... advance our system-wide understanding of complex biological net- works [17]. In this work, we present a systems biology approach focused on the dynamic modelling of cold-induced r...

Ngày tải lên: 14/02/2014, 22:20

... regulated by the factor in our systems biology- based network and in the co-expression network, respectively. Transcription factors in our systems biology- based network that are not in the co-expression ... Arabidopsis, and(3)tounderstandtheregulatorycomplexityin leaves by comparing systems biology and traditional bioinformatics as methods for detecting target genes f...

Ngày tải lên: 11/08/2014, 11:21

... (drain- ing sinus, pneumonia, etc.). Despite the retrospective design of our study and the limited possibility of in- terpreting these findings and their causes, this rate indicates that these ... Despite the retrospective study design and the limited possibility of interpreting these find- ings and their causes, this rate indicates that patients suffering from late hip joint inf...

Ngày tải lên: 26/10/2012, 09:53

... against Cirrhosis), is a multicenter study of the potential benefit of prolonged peginterferon therapy in mitigating the progression of fibrotic liver disease. [8] In this study, 391 of the ... costly and has not been studied rigorously in a randomized controlled format to assess their value and impact on efficacy of therapy although they are now widely used in patients r...

Ngày tải lên: 31/10/2012, 17:11

... ligand binding domains. By modeling the human PXR ligand binding domain we have identified and mutated two polar residues in the puta- tive ligand binding pocket which differ between the human and the ... built a homology model of human PXR in order to identify residues that were likely to be involved in ligand binding. Since the initiation of this study the crystal structure...

Ngày tải lên: 08/03/2014, 16:20