Báo cáo y học: "Protein degradation, signaling, microRNAs an

Báo cáo y học: "Protein degradation, signaling, microRNAs and cancer" ppsx

... cell growth. Transcription of the Scylla and Charybdis genes is induced by hypoxia via the hypoxia-inducible transcription factor HIF. The same induction by HIF and downstream effects on TSC1/TSC2 ... Epalinges, Switzerland), reported that these mutant embryos die at different stages of embryonic development (embryonic day (E) 10.5 for lgs1 -/- lgs2 -/- , and E14.5 for pygo1 -/- pygo2...

Ngày tải lên : 14/08/2014, 14:21

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Báo cáo y học: "HAE therapies: past present and future" ppsx

... moni- toring of airway patency. If the airway was threatened, the patient needed to be intubated by an experienced physician with the capability for emergency tracheotomy immediately available. Acute ... kinino- gen(HMWK)[58].Thereleasedbradykininmoiety potently increases vascular permeability by binding to its cognate receptor (the bradykinin B2 receptor) on vascular endothelial cells. The d...

Ngày tải lên : 08/08/2014, 21:20

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Báo cáo y học: "Metabonomics-based Omics Study and Atherosclerosis" ppsx

... activity in tissues of lean and obese mice. International journal of obesity and related metabolic disorders 1996, 20: 738-744 30 Lynch RM, Paul RJ:Compartmentation of glycolytic and glycogenolytic ... Thrombosis, and Vascular Biology 2005, 25:2135-2142 29 Bryson JM, Cooney GJ, Wensley VR, Phuyal JL, Caterson ID:The effects of the inhibition of fatty acid oxidation on pyruvate d...

Ngày tải lên : 10/08/2014, 09:22

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Báo cáo y học: " Green tea (Camellia sinensis) and cancer prevention: a systematic review of randomized trials and epidemiological studies" ppt

... 24(3):192-195. 29. Hoshiyama Y, Kawaguchi T, Miura Y, Mizoue T, Tokui N, Yatsuya H, Sakata K, Kondo T, Kikuchi S, Toyoshima H, Hayakawa N, Tamakoshi A, Ohno Y, Yoshimura T: A prospective study of stomach ... 16:185-192. 27. Sun CL, Yuan JM, Lee MJ, Yang CS, Gao YT, Ross RK, Yu MC: Uri- nary tea polyphenols in relation to gastric and oesophageal cancers: a prospective study of men in Shan...

Ngày tải lên : 13/08/2014, 15:21

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Báo cáo y học: "Elevated extracellular matrix production and degradation upon bone morphogenetic protein-2 (BMP-2) stimulation point toward a role for BMP-2 in cartilage repair and remodeling" pps

... chondrocytes exposed to TNF-α. When BMP activity was blocked by noggin during TNF-α exposure, the proteoglycan synthesis was reduced. BMP-2 is apparently necessary for cartilage integrity and improves ... reversed by day 21 to levels lower than those of controls. (a) NITEGE staining was low on day 3 but was clearly elevated by day 7 on the patella. This was reduced by more than 50% by da...

Ngày tải lên : 09/08/2014, 10:21

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Báo cáo y học: "Protein Never in Mitosis Gene A Interacting-1 regulates calpain activity and the degradation of cyclooxygenase-2 in endothelial cells" pot

... Takahashi S, Yokoyama M, Arai I, Higuchi S, Otomo S: NS- 398, a new anti-inflammatory agent, selectively inhibits pros- taglandin G/H synthase/cyclooxygenase (COX-2) activity in vitro. Prostaglandins ... COX-2 in acute and chronic inflammatory responses in the vasculature are complicated by multiple primary and secondary stimuli that may be present, and by cellular factors, such as supp...

Ngày tải lên : 11/08/2014, 08:22

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Báo cáo Y học: Protein methylation as a marker of aspartate damage in glucose-6-phosphate dehydrogenase-deﬁcient erythrocytes docx

... Borchardt, R.T. (1990) Mechanism of the synergistic antiviral and cytostatic activity of (RS)-3-(adenin-9-yl)-2-hydroxypropanoic acid isobutyl ester and D , L -homocysteine. Biochem. Pharmacol. 39, 195–202. 24. ... in erythrocyte cytosol, as detailed in Materials and methods. (B) Membrane protein methylation levels were deter- mined in two diﬀerent erythrocyte age/density fractions obta...

Ngày tải lên : 08/03/2014, 22:20

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Báo cáo Y học: RING ﬁnger, B-box, and coiled-coil (RBCC) protein expression in branchial epithelial cells of Japanese eel, Anguilla japonica pot

... eRBCC, purified it by affinity chro- matography, and confirmed its specificity by Western blot analysis using extracts of COS-7 cells expressing exogenous eRBCC (Fig. 7). Affinity purification of the ... suggested by differential display, was confirmed by Northern blot analysis (Fig. 1) and RNase protection analysis (Fig. 5). Immu- nohistochemistry suggested that the eRBCC-expressing cells are m...

Ngày tải lên : 17/03/2014, 10:20

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Báo cáo Y học: GPI-microdomains (membrane rafts) and signaling of the multi-chain interleukin-2 receptor in human lymphoma/leukemia T cell lines doc

... structures in the plasma memb rane of lymphocytes revealed by ﬂow cytometric energy transfer, scanning force- and transmission electron-microscopic analyses. Cytometry 33, 225–233. 23. Eicher, D.M. ... Simons, K. (1999) Clusters of glycolipid and glycosylphosphatidyl-inositol-anchored proteins in lymphoid cells: accumulation of actin regulated by local tyrosine phosphorylation. Eur. J. Im...

Ngày tải lên : 17/03/2014, 23:20

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Báo cáo y học: "Antigen receptor signaling in the rheumatic diseases" doc

... family kinases (SFKs), which, in T cells, are Lck and Fyn. Dually phosphorylated ITAMs, in turn, form docking sites for the tandem SH2 domains of Syk family kinases, ZAP-70 and Syk. The Syk kinases ... primary human lymphocytes and recent advances in human genetics. B-cell receptor hyper-responsiveness is identified as a nearly universal characteristic of systemic lupus erythema- tosus...

Ngày tải lên : 09/08/2014, 01:22

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