... especially in the early stages of bone and joint destruction. Radio- graphs still remain the imaging examination of choice for gouty arthritis although advanced imaging techniques may be used. The ... three-fold in the UK over 20 years of follow-up [10]. This rise may be attrib- uted in part to the continuous aging of the population as well as the widespread use o...
Ngày tải lên: 25/10/2012, 10:06
... strand-displacement syn- thesis, leading to the formation of a dimer duplex inter- mediate (dRF) in which two unit length copies of the genome are joined by a single duplex copy of the original 3' palindrome ... which has a size of ~250 bp; two molecules of the hairpin should be generated for every copy of the stuffer sequence, there- with the intensity of th...
Ngày tải lên: 19/06/2014, 08:20
báo cáo hóa học:" Possible active origin of replication in the double stranded extended form of the left terminus of LuIII and its implication on the replication model of the parvovirus" ppt
... strand-displacement syn- thesis, leading to the formation of a dimer duplex inter- mediate (dRF) in which two unit length copies of the genome are joined by a single duplex copy of the original 3' palindrome ... provided in trans. This extended hairpin, capable of acting as an origin of replication, lacks the arrangement of the specific domains present in t...
Ngày tải lên: 20/06/2014, 04:20
Báo cáo y học: "Efficacy and safety of aripiprazole in the treatment of bipolar disorder: a systematic review" pdf
... (dehydro- genation, hydroxylation, and N-dealkylation), mainly by cytochrome P450 2D6 (CYP2D6) and cytochrome P450 3A4 (CYP3A4) [60]. The parenteral drug is excreted only in traces. There is only ... (7-(4-[4-(2,3-dichlorophenyl)-1-piperazi- nyl]butyloxy)-3,4-dihydro-2 (1H)-quinolinone (OPC- 14597), is a derivative of the dopamine autoreceptor ago- nist 7-(3-[4-(2,3-dimethylphenyl)pip...
Ngày tải lên: 08/08/2014, 23:21
Báo cáo y học: "Expression and regulation of neurotrophins in the nondegenerate and degenerate human intervertebral disc" pdf
... for the proinflammatory cytokines TNFα and IL-1β in innervation of the IVD [22] and in degeneration of the IVD has been demonstrated by a number of authors [23-25]. Addition- ally these cytokines ... Immunohistochemistry showed expression of NGF and BDNF in the native chondrocyte-like cells in all regions of the IVD and in all grades of degeneration. Interestin...
Ngày tải lên: 09/08/2014, 11:20
Báo cáo y học: "Downstream molecular pathways of FLT3 in the pathogenesis of acute myeloid leukemia: biology and therapeutic implications" pps
... receptor- bound protein (Grb2) and Srcfamilytyrosinekinase, and results in the phosphorylation of these proteins [38]. These actions affect the activation of further down- stream PI3K/protein kinase B (Akt) ... transplantation therapy in the 1980s. However, the clinical outcome of AML has not improved since the 1990s, with the exception of the identification of all...
Ngày tải lên: 10/08/2014, 21:23
Báo cáo y học: "Assessing the origin of species in the genomic era" doc
... Frequently, this goal has been translated into the study of the genetic basis of species differ- ences, especially the genetic causes of inviability or sterility in hybrids between species. Despite ... Drosophila. The resulting con- temporary studies of the genetics of speciation most fre- quently involve detailed linkage-mapping analyses of the quantitative trait...
Ngày tải lên: 14/08/2014, 14:21
Tài liệu Báo cáo Y học: Soluble silk-like organic matrix in the nacreous layer of the bivalve Pinctada maxima A new insight in the biomineralization field pptx
... alanine (6.5%). Thus, the alanine and glycine content of WSM was rather similar to that of EDTA-IM. In spite of the presence of mineral, it was possible to analyze the amino acid composition of the ... revealed the predominance of two amino acids: alanine (39.2%) and glycine (30%). Interestingly, the proportions are very similar to those found in WSM for alanine an...
Ngày tải lên: 21/02/2014, 01:21
Báo cáo y học: "Assessing post-traumatic stress disorder in South African adolescents: using the child and adolescent trauma survey (CATS) as a screening tool" docx
... differing rates of PTSD between the K-SADS and the CATS (using a cut-off 27 on the CATS), suggests that this cut-off may be too high in our setting. The ROC analysis yielded a cut-off of 15 on the CATS. ... asked to indi- cate how often they are jumpy and nervous, or how often they sleep poorly – never, rarely, sometimes or often. Each of the DSM-IV PTSD criterion variable...
Ngày tải lên: 08/08/2014, 21:20
Báo cáo y học: "Cold hands — strained heart? Advances in the management of Raynaud’s phenomenon and pulmonary hypertension" ppt
... processes underlying RP and PAH contribute to the familiar pattern of skin, renal and gastrointestinal pathology. The emergence of effective and conveniently administered therapy for PAH increases the importance ... vasculopathy of SScl may also be modifiable. In the characteristic microangiopathy of SScl, luminal narrowing results from a combination of intimal proliferati...
Ngày tải lên: 09/08/2014, 06:23