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Báo cáo y học: "Assessing the origin of species in the genomic era" doc

Báo cáo y học:

Báo cáo y học: "An unusual case of gout in the wrist: the importance of monitoring medication dosage and interaction. A case report"

... especially in the early stages of bone and joint destruction. Radio-graphs still remain the imaging examination of choice forgouty arthritis although advanced imaging techniquesmay be used. The ... three-fold in the UKover 20 years of follow-up [10]. This rise may be attrib-uted in part to the continuous aging of the population aswell as the widespread use of diuretics for treatment of hypertension ... a clinical syndrome caused by the deposition of monosodium urate monohydrate crystals into synovial,bursal, and cartilaginous tissue. The underlying metabolicdisorder is hyperuricemia. The...
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Báo cáo sinh học:

Báo cáo sinh học: " Possible active origin of replication in the double stranded extended form of the left terminus of LuIII and its implication on the replication model of the parvovirus" pptx

... strand-displacement syn-thesis, leading to the formation of a dimer duplex inter-mediate (dRF) in which two unit length copies of the genome are joined by a single duplex copy of the original3' palindrome ... whichhas a size of ~250 bp; two molecules of the hairpin shouldbe generated for every copy of the stuffer sequence, there-with the intensity of the band corresponding to the hair-pin is expected ... provided in trans. This extended hairpin, capable of acting as an origin of replication, lacks the arrangement of the specific domains present in the dimer duplex intermediate of MVM, the only active...
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báo cáo hóa học:

báo cáo hóa học:" Possible active origin of replication in the double stranded extended form of the left terminus of LuIII and its implication on the replication model of the parvovirus" ppt

... strand-displacement syn-thesis, leading to the formation of a dimer duplex inter-mediate (dRF) in which two unit length copies of the genome are joined by a single duplex copy of the original3' palindrome ... provided in trans. This extended hairpin, capable of acting as an origin of replication, lacks the arrangement of the specific domains present in the dimer duplex intermediate of MVM, the only active ... whichhas a size of ~250 bp; two molecules of the hairpin shouldbe generated for every copy of the stuffer sequence, there-with the intensity of the band corresponding to the hair-pin is expected...
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Báo cáo y học:

Báo cáo y học: "Efficacy and safety of aripiprazole in the treatment of bipolar disorder: a systematic review" pdf

... (dehydro-genation, hydroxylation, and N-dealkylation), mainly bycytochrome P450 2D6 (CYP2D6) and cytochrome P4503A4 (CYP3A4) [60]. The parenteral drug is excreted only in traces. There is only ... (7-(4-[4-(2,3-dichlorophenyl)-1-piperazi-nyl]butyloxy)-3,4-dihydro-2 (1H)-quinolinone (OPC-14597), is a derivative of the dopamine autoreceptor ago-nist 7-(3-[4-(2,3-dimethylphenyl)piperazinyl]propoxy)-2(1H)-quinolinone ... dopamineautoreceptor agonists (in spite of being efficacious in the treatment of psychosis) might potentially increase the riskfor exacerbation of psychosis through stimulation of post-synaptic...
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Báo cáo y học:

Báo cáo y học: "Expression and regulation of neurotrophins in the nondegenerate and degenerate human intervertebral disc" pdf

... for the proinflammatory cytokines TNFα and IL-1β in innervation of the IVD [22] and in degeneration of the IVD hasbeen demonstrated by a number of authors [23-25]. Addition-ally these cytokines ... Immunohistochemistry showed expression of NGF andBDNF in the native chondrocyte-like cells in all regions of the IVD and in all grades of degeneration. Interestingly only BDNFsignificantly increased with the ... performed the majority of the laboratory work and analysis, and drafted the manuscript. AJF helped to secure funding, participated in the design of the study and interpretation of data, and assisted in the...
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Báo cáo y học:

Báo cáo y học: "Downstream molecular pathways of FLT3 in the pathogenesis of acute myeloid leukemia: biology and therapeutic implications" pps

... receptor-bound protein (Grb2) and Srcfamilytyrosinekinase,and results in the phosphorylation of these proteins[38]. These actions affect the activation of further down-stream PI3K/protein kinase B (Akt) ... transplantation therapy in the 1980s. However, the clinical outcome of AML hasnot improved since the 1990s, with the exception of the identification of all-trans-retinoic acid therapy for APL.Currently, ... heterocycliccompounds containing components that structurallymimic the purine ring of adenosine and become insertedinto the ATP-binding site of FLT3 [69]. Among thesecompounds, SU11248 (sunitinib),...
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Báo cáo y học:

Báo cáo y học: "Assessing the origin of species in the genomic era" doc

... Frequently, this goal has beentranslated into the study of the genetic basis of species differ-ences, especially the genetic causes of inviability or sterility in hybrids between species. Despite ... Drosophila. The resulting con-temporary studies of the genetics of speciation most fre-quently involve detailed linkage-mapping analyses of the quantitative trait loci (QTLs) underlying the isolating ... Ever since Darwin laid out overwhelming evidence for the mutability of species, biologists have sought to explain the forces driving the genesis of new species and the geneticchanges involved in...
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Tài liệu Báo cáo Y học: Soluble silk-like organic matrix in the nacreous layer of the bivalve Pinctada maxima A new insight in the biomineralization field pptx

Tài liệu Báo cáo Y học: Soluble silk-like organic matrix in the nacreous layer of the bivalve Pinctada maxima A new insight in the biomineralization field pptx

... alanine (6.5%). Thus, the alanine and glycinecontent of WSM was rather similar to that of EDTA-IM. In spite of the presence of mineral, it was possible to analyze the amino acid composition of the ... revealed the predominance of two amino acids: alanine (39.2%) andglycine (30%). Interestingly, the proportions are very similarto those found in WSM for alanine and glycine.Curiously, the presence ... confirms the hypothesis that the silk isindeed present in two states, soluble and insoluble, the latterbeing in some way protected from dissolution in water. The peculiarity of the WSM led to the...
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Báo cáo y học:

Báo cáo y học: "Assessing post-traumatic stress disorder in South African adolescents: using the child and adolescent trauma survey (CATS) as a screening tool" docx

... differing rates of PTSD between the K-SADS and the CATS (using a cut-off 27 on the CATS), suggests that thiscut-off may be too high in our setting. The ROC analysisyielded a cut-off of 15 on the CATS. ... asked to indi-cate how often they are jumpy and nervous, or how oftenthey sleep poorly – never, rarely, sometimes or often. Each of the DSM-IV PTSD criterion variables is represented byat least ... indicates that the CATS may bebetter utilized as a PTSD screening device (as suggested byits author), with a cut-off threshold of 15 instead of the original threshold of 27, in the South African...
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Báo cáo y học:

Báo cáo y học: "Cold hands — strained heart? Advances in the management of Raynaud’s phenomenon and pulmonary hypertension" ppt

... processesunderlying RP and PAH contribute to the familiar pattern of skin, renal and gastrointestinal pathology. The emergence of effective and conveniently administered therapy for PAHincreases the importance ... vasculopathy of SScl mayalso be modifiable. In the characteristic microangiopathy of SScl, luminalnarrowing results from a combination of intimal proliferation,medial hypertrophy and adventitial ... cell dysfunction is characterised bydecreased production of the vasodilators nitric oxide andprostacyclin, and by enhanced release of endothelin-1.Endothelial cell dysfunction influences the...
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