Báo cáo y học: "SINEs point to abundant editing in the human

Báo cáo y học: "SINEs point to abundant editing in the human genome" ppt

... gene silencing [5]. In the past several years, interest in the prevalence of editing in the human genome and in the identity of endogenous editing substrates has grown. Recent work using computa- tional ... RNAs (dsRNAs) in cells, especially those in the nucleus, are susceptible to base editing in which adenosines are deaminated to inosines by enzymes known...

Ngày tải lên : 14/08/2014, 14:21

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Báo cáo khoa học: "Personalising speech-to-speech translation in the EMIME project" pptx

... currently using Google trans- late 3 . 3 Demonstrations to show 3.1 Monolingual systems In robust speech synthesis, a computer can learn to speak in the desired way after processing only a relatively ... annotated by applying ASR. By elimi- nating the need for human intervention it becomes possible to perform voice adaptation for TTS in almost real-time. The target in t...

Ngày tải lên : 17/03/2014, 00:20

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Báo cáo y học: " Detection of a gammaretrovirus, XMRV, in the human population: Open questions and implications for xenotransplantation" ppsx

... murine leu- kemia virus sequences were detecte d. The authors came to the conclusion the XMRV is not a contributory factor in the pathogenesis of CSF [10]. In light of these results, the finding ... from one study in the USA were virus positive [3]. Why is the virus common in the USA but rare in Europe ? Are there speci fic populations of rodents in the USA rel...

Ngày tải lên : 12/08/2014, 23:23

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Báo cáo y học: "Gene regulation and signal transduction in the immune system" pptx

... promoting B-cell development by restraining the expression of pro-myeloid factors (such as Gfi1), and acting directly to induce the recombinase (Rag) genes and thereby recombination at the immunoglobulin ... catenin-like protein 1) as an AID-interacting protein. Interestingly, he found that an AID mutant deficient in CTNNBL1 binding retains deamination activity but is impaired in...

Ngày tải lên : 14/08/2014, 20:22

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$Báo cáo y học: "Differential responsiveness to immunoablative therapy in refractory rheumatoid arthritis is associated with level and avidity of anti-cyclic citrullinated protein autoantibodies: a case study" pps$

Báo cáo y học: "Differential responsiveness to immunoablative therapy in refractory rheumatoid arthritis is associated with level and avidity of anti-cyclic citrullinated protein autoantibodies: a case study" pps

... 0.043). To study the reactivation of humoral autoimmunity after immunoablative therapy, we ana- lyzed the avidity of reappearing ACPA-IgG autoantibodies by dichotomizing patients according to their ... by the emergence of low avidity ACPA-IgG autoantibodies, indicative of a newly generated autoimmune response during synovial inflammation. These data give novel insight into the h...

Ngày tải lên : 09/08/2014, 10:21

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Báo cáo y học: "Ultrasound properties of articular cartilage in the tibio-femoral joint in knee osteoarthritis: relation to clinical assessment (International Cartilage Repair Society grade)" pptx

... a reduction in the elastic restraint of the collagen network, allowing the glycosaminoglycans within the fibrillated tissue to swell to a greater degree of hydration [28]. Because the speed of ... Site-specific differences in signal intensity suggest that the superficial collagen network may be maintained in cartilage of the lateral condyle but may deteriorate in c...

Ngày tải lên : 09/08/2014, 10:23

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Báo cáo y học: "Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination" pot

... experimental autoimmune encephalomyelitis (EAE) using myelin and synovial antigen arrays. (a, b) Synovial and (d, e) myelin arrays were produced by printing synovial and myelin peptides and proteins in ... mice. Epitope spreading of autoantibody responses in EAE We used 406 antigen myelin proteome arrays to examine the pattern of epitope spreading of the autoantibody response in...

Ngày tải lên : 09/08/2014, 13:22

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Báo cáo y học: "Differential cellular FGF-2 upregulation in the rat facial nucleus following axotomy, functional electrical stimulation and corticosterone: a possible therapeutic target to Bell’s pals" doc

... cells following facial nerve axotomy indicating a possible additional autocrine role. It was reported that the FGF-2 synthesized in the ton- gue may be retrogradaly transported to the hypoglossal nucleus ... Bisby MA, Kreutzberg GW: Changes in cytoskeletal proteins in the rat facial nucleus following axotomy. J Neurosci 1988, 8:3181-3189. 44. Bisby MA, Tetzlaff W: Changes in...

Ngày tải lên : 10/08/2014, 10:20

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Báo cáo y học: "Hemangioma related to Maffucci syndrome in a man: a case report" docx

... related to Maffucci syndrome in a man: a case report Takeshi Kondo Abstract Introduction: Maffucci syndrome is a rare clinical entity (app roximately 200 cases have been reported in the medical ... of the hemangiomas was removed and examined pathologically. The morphological picture was an admixture of cavernous hemangioma and spindle cell hemangioma without cytological atypia or...

Ngày tải lên : 10/08/2014, 23:21

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Báo cáo y học: " Therapeutic approach to Gradenigo''''s syndrome: a case report." pptx

... apex only by the dura mater, hence their vulnerability to inflammatory processes occurring within this region [3]. The involvement of the sixth cranial nerve is caused by the spread of inflammation ... effectively drained in select cases using an infralabyrithine approach between the posterior semicircular canal and the jugular bulb, without necessarily sacrificing the funct...

Ngày tải lên : 11/08/2014, 12:20

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