Báo cáo y học: "Large-scale discovery and validation of functional elements in the human genome" ppt
Báo cáo y học: "Large-scale discovery and validation of functional elements in the human genome" ppt
... goal of identifying all the functional
elements in the human genome. The functional elements
discussed at the meeting included protein-coding genes, reg-
ulatory elements, RNA genes and DNA sequences ... [http://
www.genome.gov/10005107]. The consortium, organized
and funded by the National Human Genome Research Insti-
tute, is initially focusing on designated...
Báo cáo y học: " Smoking-mediated up-regulation of GAD67 expression in the human airway epithelium" doc
... expression only of GAD67, a gene
controlling the synthesis of GABA [2]. A striking
increase in gene expression levels of GAD67 was
observed in the large and small airway epithelium of
healthy smokers ... only in the brain, but also in
other organs, including liver,kidney,pancreas,testis,
oviduct, adrenal, and lung [3,4].
GABAergic System in the Lung
In the lu...
Báo cáo y học: " Design, assembly, and validation of a nose-only inhalation exposure system for studies of aerosolized viable influenza H5N1 virus in ferrets" ppt
... leaks in the air-handling and sys-
tem components after assembly of the NBIES. Leaks
detected (if any) were sealed and the system repeatedly
retested to verify remediation. To improve safety and
extend ... process on the viability of the
entrained agent in the impingers can only be inferred,
collection efficency of our sampling system using funda-
mental mathematic...
Báo cáo y học: "Optimal design and validation of antiviral siRNA for targeting HIV-1" potx
... study was supported in part by grants from the Ministry of Education,
Culture, Sports, Science and Technology of Japan (to YN, KU-T, KS, and
YT), the Ministry of Health, Labour and Welfare of ... con-
tains the siRNA target site was cotransfected into HeLa
cells with the corresponding siRNA, and the mRNA cleav-
age activity of the siRNA was evaluated by measu...
Báo cáo y học: "Refractive Status and Prevalence of Refractive Errors in Suburban School-age Children"
... t
influence on the prevalence of hyperopia and myopia.
As age increased, the prevalence of hyperopia signif-
icantly decreased and the prevalence of myopia in -
creased. Based on the definitions ... China, especially the de-
veloping regions.
Western China is very vast (6.8 million square
kilometers, accounting for 71% of the area in main-
land China), and in...
Báo cáo y học: "Glutamatergic deficits and parvalbumin-containing inhibitory neurons in the prefrontal cortex in schizophrenia" ppt
... quantification of axonal boutons afforded us
a higher sensitivity in detecting differences in the present
study. In the context of our finding, it is interesting to note
that, a single polymorphism in the ... furnished by other pyramidal neurons,
located both within the PFC and in other cortical areas
[10-12]. The integrity of PFC functions therefore depends
on th...
Báo cáo y học: "Production, purification and characterization of polyclonal antibody against the truncated gK of the duck enteritis virus" pps
... waterfowl. With the purpose of decreasing economic
losses in the commercial duck industry, studying the unknown glycoprotein K (gK) of DEV may be a new method
for preferably preventing and curing this ... entry of free viruses, and the maturation or
egress of the virus [8,9]. Glycoprotein K is one of the
major glycoproteins encoded by the DEV-gK gene,
which is lo...
Báo cáo y học: "Detection, characterization and regulation of antisense transcripts in HIV-1" ppt
... have
helped in drafting and finalizing the manuscript and pro-
vided important input on the design of the study. BB con-
ceived the study, participated in its coordination, and
helped in drafting the ... 3' end of the ASP ORF and were likely
determinant for the polyadenylation of the antisense tran-
script [4]. We next searched for the 3' end o...
Báo cáo khoa học: Identification and characterization of important residues in the catalytic mechanism of CMP-Neu5Ac synthetase from Neisseria meningitidis potx
... studies of Mosimann et al. [12], the
hydroxyl group of Tyr179 lies within hydrogen-bonding
distance of O7 and O9 of the glyceryl moiety of
Neu5Ac, and a network of noncovalent bonds between
enzyme and ... con-
structed and the kinetic parameters of the purified
F192A and F193A mutant enzymes were obtained in
the same way as the wild-type enzyme (Table 1)....
Báo cáo khoa học: Protein folding and disulfide bond formation in the eukaryotic cell pptx
... exciting area of research forwards into the
future. Indeed, obtaining accurate measurements of the
concentrations, distributions and flux of all the main
players involved in protein folding in the ... control the folding of heavy chain and ensure the
fidelity of immunoglobulin assembly. Mol Biol Cell 10,
2209–2219.
12 Kaloff CR & Haas IG (1995) Coordination of...