Báo cáo y học: "Variation in tissue-specific gene expression among natural populations" ppt

... A2 y F4 Cystathionine beta synthase Cystathionine-beta-synthase z K11 Cold inducible RNA binding Cold inducible RNA-binding protein; (CIRBP) glycine-rich RNA binding protein; aa F2 Hepatocyte ... binding H6 Fatty acid binding protein H6-isoform tt O10 Fatty acid binding heart Heart-type fatty acid-binding protein (H-FABP) uu D9 Fatty acid syn Fatty acid synthase vv F9 Glutamate decarboxylas...

Ngày tải lên: 14/08/2014, 14:21

... persistent redundancy among duplicates genes in yeast. PLoS Genet 2008, 4:e1000113. 27. Gao L-Z, Innan H: Very low gene duplication rate in the yeast genome. Science 2004, 306:1367-1370. 28. Lin Y- S, Byrnes ... it's not what you think it is. Nat Genet 2000, 25:3-4. 23. Byrne K, Wolfe KH: The Yeast Gene Order Browser: combin- ing curated homology and syntenic context reveals...

Ngày tải lên: 14/08/2014, 21:20

... controls [18]. The microarray assay used (Panorama Cytokine Gene Array membranes; Sigma Genosys, Inc) included 375 genes enriched in cytokines, chemokines, cell surface 286 ably derive from studies ... discerning gene expression relevant to disease-specific molecular pathways. Interferon-induced gene expression in rheumatic diseases A gene expression profile identified by mi...

Ngày tải lên: 09/08/2014, 01:23

... their own pro-inflammatory cytokines, including IL-1β and tumor necrosis factor-α, under the influence of proinflammatory cytokines present in the synovial tissues of patients with early OA [23,24], ... cur- Figure 5 Gene expression pattern of chondrocytes after in vivo inoculation in scaffoldsGene expression pattern of chondrocytes after in vivo inoculation in scaffolds. Chon...

Ngày tải lên: 09/08/2014, 10:20

... changes in degenera- tion include altered matrix synthesis, including a decrease in glycosaminoglycan production and an increase in collagen type I within the NP, and upregulation of matrix-degrading enzymes ... AJ: Interleukin-1 receptor antagonist delivered directly and by gene therapy inhibits matrix degradation in the intact degenerate human interverte- bral disc: an in situ z...

Ngày tải lên: 09/08/2014, 14:20

... Strain differences in the pattern and intensity of wheel running activity in laboratory rats. Experientia 1991, 47:593-598. 23. Siebert U, Wollnik F: Wheel-running activity rhythms in two inbred ... Variation in circadian rhythms and nocturnality may, hypothetically, be related to or independent of genetic variation in photoperiodic mediation of seasonal changes in physiology and...

Ngày tải lên: 10/08/2014, 09:20

... concentrations during the first 10 days of intensive care unit (ICU) stay. There was an average decrease of 16g/l in haemoglobin concentrations in all patients admitted to the ICU over the 10-day monitoring interval. Institution ... determine the degree of interinstitutional transfusion practice variation and reasons why red cells are administered in critically ill patients. Study desig...

Ngày tải lên: 12/08/2014, 18:20

... (CNE-C) in the IL4 gene, may influence susceptibility in combination with other variation in IL4, or may merely be in LD with other variation in the gene that influences susceptibility to asthma ... iden- tifying SNPs. Genotyping The genotyping methods used in this study are described in Additional File Table 2. In addition to four SNPs in or flanking conserved sequences,...

Ngày tải lên: 12/08/2014, 18:20

... be explained in several ways. First, the interventions do not affect outcome. Certainly, there is mounting evidence that some of the studied interventions, such as application of the pulmonary artery ... outcome. Second, any beneficial effects are offset by unwanted side effects. For example, better titration of care secondary to information gained by pulmonary artery catheter use may be of...

Ngày tải lên: 12/08/2014, 19:22

... binding site, or both. Certainly brain-derived envelopes are more likely to carry the N283 in the C2 CD4 binding site as reported by Dunfee et al. [35] and confirmed by our group Sensitivity ... sensitivity must there- fore be due to other mechanisms but could be explained by changes in envelope: CD4 affinities. Protection of the CD4 binding site may be conferred by V1V2 shielding or by g...

Ngày tải lên: 13/08/2014, 06:20