Báo cáo y học: "Insights into vertebrate evolution from the chicken genome sequence" ppt
Báo cáo y học: "Insights into vertebrate evolution from the chicken genome sequence" ppt
... gallus). Remarkably, barely one year
later an initial draft assembly based on a 6.6X coverage of
the genome was released into the public databases. The
International Chicken Genome Sequencing ... importance, and they have long
been a model for biological research in fields ranging from
embryology and development to virology and cancer. In
addition, the phylogenetic position...
Tài liệu Báo cáo Y học: Insights into the reaction mechanism of Escherichia coli agmatinase by site-directed mutagenesis and molecular modelling ppt
... metal-bound hydroxide for optimal
attack on the guanidinium carbon of agmatine. Thus, the
disruption of this hydrogen bond is the likely cause of the
greately decreased catalytic efficiency of the D153N ... indicating that the environ-
ment of tryptophan residues is essentially conserved in the
mutant enzyme. On the other hand, the absence of major
differences in the CD spec...
Báo cáo y học: "Insights into spatial configuration of a galactosylated epitope required to trigger arthritogenic T-cell receptors specific for the sugar moiety" ppsx
... All of these T cells strictly
recognized the carbohydrate moiety linked to Hyl
264
within the
CII256–270 epitope because they were activated neither by
the unglycosylated peptide nor by the peptide ... ability to trigger the A9.2 clone and hybri-
domas. In addition to hydroxylation followed by glycosylation
of Lys
264
, the CII256–270 peptide may undergo hydroxylation
of Pro
258...
Báo cáo y học: " Insights into endocrine-immunological disturbances in autoimmunity and their impact on treatment" doc
... the circadian increase of proinflammatory
cytokine levels, and therefore the consequently observed
clinical signs and symptoms of the disease, than to treat
these signs and symptoms once they ... proinflammatory cytokines and
symptoms of RA, such as morning stiffness [11,12]. Several
of these cytokines are highly elevated in patients with active
RA in the early hours of the day, but...
Báo cáo y học: "Insights into the regulation of intrinsically disordered proteins in the human proteome by analyzing sequence and gene expression data" potx
... stability values. (d) The percentage of transcripts likely to be regulated by miRNA (y- axis) for the transcripts encoding the highly ordered and
the highly disordered proteins. (e) The percentage ... of being removed from the cell, as
they are likely to have a higher density of ubiquitination sites.
The (80,100]% disorder category is most likely to have the
highest density...
Tài liệu Báo cáo Y học: Trehalose-based oligosaccharides isolated from the cytoplasm of Mycobacterium smegmatis Relation to trehalose-based oligosaccharides attached to lipid docx
... 269) 3143
The origin of these cytosolic oligosaccharides is not
known. They could be synthesized in the cytosol by
glycosyltransferases which add glucosyl or galactosyl resi-
dues to the free ... established enzymes and the
sequences obtained from the Mycobacterium tuberculosis
genome [24]. One of these pathways involves the direct
rearrangement of the a1,4-glucosidic linkag...
Báo cáo Y học: Thermal stability of peroxidase from the african oil palm tree Elaeis guineensis pdf
... calculated from the spectral parameter used to follow
denaturation (y) prior to the minimization procedure,
according to the expression:
F
U
¼ y À y
N
Þ= y
U
À y
N
Þð6Þ
where y
N
¼ a
1
+ a
2
T and y
U
¼ ... peroxidases can be used in the synthesis of
polyaniline in the presence of hydrogen peroxide as a reduc-
ting substrate and sulfonated polystyrene and poly(vinyl-
pho...
Báo cáo y học: "Novel self-epitopes derived from aggrecan, fibrillin, and matri" ppt
... be a target of primary autoreactivity. The
induction of the pro-inflammatory cytokines IFN-γ/IL-17 and
inhibition of the anti-inflammatory cytokine IL-10 indeed sug-
gest the induction of autoaggressive ... pathology is the 'molecular mimicry' scenario:
activation of autoreactive lymphocytes by structurally similar
antigenic determinants of infectious pathogens [16,17].
Mo...
Báo cáo y học: "Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis" pdf
... that the former con-
tains novel amino acids and domain structures typically
derived from intron fusion. These alterations may subsequently
alter the functionality of the ASV as compared with the ... holds
the patents related to the content of the manuscript.
Authors' contributions
HMS designed the study. PJ assisted in the study design,
oversaw the project running...
Báo cáo y học: "An important step towards completing the rheumatoid arthritis cycle" pptx
... innocent inflammation of the joint or other tissue in
the body leads to infiltration of inflammatory cells (granulo-
cytes, monocytes, lymphocytes). In normal situations many of
the infiltrating cells ... Granulocytes and monocytes,
and macrophages emerging from monocyte differentiation,
contain citrullinating peptidylarginine deiminase (PAD)
enzymes. These enzymes are activated by t...
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