Báo cáo y học: "The latest buzz in comparative genomics" potx
... all sorts. Its interesting and diverse biology and ease of breeding in a variety of con- ditions has made Drosophila a favorite laboratory model organism. As the leading player in its genus, Drosophila melanogaster ... 2000, 287:2185-2195. 2. Dobzhansky T: Genetics and the Origin of Species. New York: Colum- bia University Press; 1937. 3. Lewontin RC, Hubby JL: A molecular approach to the...
Ngày tải lên: 14/08/2014, 14:21
... biological science community, chiefl y because they saw it as taking money and attention away from important fundamental research and channeling it into lower-quality, clinically oriented studies ... any new money to pay for it. So the money must come from somewhere, and the big fear among many in the scientifi c community is that it will come from the pool of individual investigato...
Ngày tải lên: 09/08/2014, 20:21
... of compensatory changes [11]. In summary, drug hypersus- ceptibility mutations which reduce viral fitness are diffi- cult to maintain in the predominant virus population in multiple pretreated patient. In ... Virtual Phenotype™(Virco). The clinical outcome of the L76V-adapted follow-up therapy was determined by monitoring viral load for 96 weeks. Conclusions: In this analysis, the m...
Ngày tải lên: 10/08/2014, 05:22
Báo cáo y học: "The patient perspective in research on major depression Pim Cuijpers" pps
... Banfield in BMC Psychiatry about information needs of people with depression [1]. They show that despite the hundreds of randomized trials examining the effects of pharmacotherapy and psychotherapies ... of medications. Only these issues can help us understand Correspondence: p.cuijpers@psy.vu.nl Pim Cuijpers, professor of Clinical Psychology, EMGO Institute, VU University Amsterdam and VU...
Ngày tải lên: 11/08/2014, 15:22
Báo cáo y học: " The working alliance in a randomized controlled trial comparing online with face-to-face cognitive-behavioral therapy for depression" pptx
... presenting general information about CBT and its effects in treating depression, and giving an outline of the study. Participants indicated their interest in the study by contacting the intake ... program. J Consult Clin Psych 1996, 64:532-539. 18. Cook JE, Doyle C: Working alliance in online therapy as compared to face- to-face therapy: preliminary results. Cyberpsychol Behav. 2002...
Ngày tải lên: 11/08/2014, 16:21
Báo cáo y học: " The mutation T477A in HIV-1 reverse transcriptase (RT) restores normal proteolytic processing of RT in virus with Gag-Pol mutated in the p51-RNH cleavage site" ppt
... compared the intravirion accumu- lation of Pr160 Gag-Pol polyprotein proteolytic processing intermediates by preparing virions in the presence of increasing concentrations of the HIV-1 PR inhibitor ritonavir ... by enhanced chemiluminescence (ECL) using a BioRad VersaDoc Imaging System. Analysis of intravirion proteolytic processing of Pr55 Gag and Pr160 Gag-Pol polyproteins The accumulatio...
Ngày tải lên: 12/08/2014, 23:22
Báo cáo y học: " The connection domain in reverse transcriptase facilitates the in vivo annealing of tRNALys3 to HIV-1 genomic RNA" potx
... supporting the role of lysyl-tRNA synthetase (LysRS) in targeting tRN- A Lys for viral incorporation, through a specific interaction of Gag capsid sequence with LysRS in a tRNA Lys /LysRS complex ... sequence is involved in tRNA Lys3 annealing [6,16,17]. It is not known if LysRS plays any direct role in tRNA Lys3 annealing, and LysRS may be required to dissoci- ate from tRNA Lys3...
Ngày tải lên: 13/08/2014, 13:20
Báo cáo y học: "The ins and outs of translation" potx
... facilitated by a glutamine in the conserved GGQ motif in release factors. Interestingly, the ribosome- recycling step differs markedly between prokaryotes and eukaryotes. In prokaryotes, recycling requires ... eukaryotic initiation factors (eIF) 3, 1, and 1A, which explains why a ribosome- recycling factor is not found in eukaryotic cells. The many factors participating in eukaryoti...
Ngày tải lên: 14/08/2014, 08:20
Báo cáo y học: "The first decade of microbial genomics: what have we learned and where are we going next" doc
... many occasions. As pointed out by W. Ford Doolittle (Dalhousie University, Halifax, Canada), the notion of a bacterial species is classi- cally defined as a “uniform and stable way for naming groups ... variability within any given species. It is clear that a species is not adequately represented by a single genome unless the species is evolutionarily young and rela- tively monomorphic. In...
Ngày tải lên: 14/08/2014, 14:22
Báo cáo y học: "The Systemic Inflammatory Response Syndrome (SIRS) in acutely hospitalised medical patients: a cohort study"
... identified by two or more symptoms including fever or hypothermia, tachycardia, tachypnoea and change in blood leucocyte count. The relationship between SIRS symptoms and morbidity and mortality in medical ... moderately associated with infection and strongly related to 28-day mortality. Background Sepsis is a systemic inflammatory response to a confirmed or suspected infection. Clinicall...
Ngày tải lên: 25/10/2012, 09:56