Báo cáo y học: "Profiling gene expression in growth-arrested mouse embryos in diapause" potx

... [2]. Recently, a study by Hamatani et al. [3] profiled the patterns of gene expression in diapausing mouse embryos and identi- fied genes that may mediate this form of naturally induced growth ... 6:202 comment reviews reports deposited research interactions information refereed research Minireview Profiling gene expression in growth-arrested mouse embryos in diapause...

Ngày tải lên: 14/08/2014, 14:21

... include overactive inflammatory response in the form of hypercy- tokinemia (cytokine storm), that is initiated inside the infected cells or tissue in response to virus replication resulting in ... 28 genes were found to have differential expression pattern and were mainly involved in Cytokine-cytokine receptor interaction, Toll like-receptor mediated signal- ing and p53 signaling pa...

Ngày tải lên: 12/08/2014, 01:21

... the interleukin 5 gene; λ Ig: the λ -chain of immunoglobulin gene; γIg: the γ-chain of immunoglobulin gene; IFN-ind: the interferon-inducible gene 6-16; IL4R: the interleukin 4 receptor gene; ... dehydrogenase subunit 4 gene, IL5 – the interleukin 5 gene, λ Ig – the λ -chain of immunoglobulin gene, γIg – the γ-chain of immunoglobulin gene, IFN-ind – the interferone-inducible...

Ngày tải lên: 02/11/2012, 11:08

... analyzed individually. Flow cytometry analysis The cell type composition and level of protein expression for some genes in the inguinal lymph nodes were analyzed by flow cytometry. Single cell ... information regarding the pathways in which the genes are operating. Conclusion We showed that a rather simple microarray analysis is useful in identifying interesting pathways and candidate...

Ngày tải lên: 09/08/2014, 01:23

... previously reported data showing an age-related increase in OCN gene expression in OA and a decrease in controls [16]. This finding is supportive of an increase or main- tenance of bone volume in OA individuals ... combining gene expression analysis with histomorphometry allows the exploration of any relationships between gene expression and indices of bone architecture an...

Ngày tải lên: 09/08/2014, 08:23

... changes in a mouse joint instability OA model [78], suggesting a role for increased RUNX2 expression in OA pathogenesis. An important role for RUNX2 in OA pathogenesis is supported by our microarray data. ... control the expression of the target genes. Interestingly, the only gene encoding a WNT ligand, WNT5B, that was identified as being differentially expressed (upregulated i...

Ngày tải lên: 09/08/2014, 10:21

... <.05) within 21 days of pneumonectomy. Cluster analysis of the 22 genes indicated that changes in gene expression did not occur in a single phase, but in at least four waves of gene expression: ... pneumonectomy. Experimental time points were at Day0,3,6,14and21days.Day0studiedgene expression in the right lung without any prior surgery (sham thoracotomy or left pneumonecto...

Ngày tải lên: 12/08/2014, 13:22

... downregulation of decorin gene expression in COPD patients, at least partially via the Smad pathway. Our findings may explain why only a sub- set of smokers demonstrates an excess parenchymal ECM destruction ... genes under influence of TGFβ and TNF in the same direction as the control fibroblasts. As CSE exposure mainly induced inhibition of expression, it seems likely that a genera...

Ngày tải lên: 12/08/2014, 14:20

... recent study describes up-regulation of select inflammatory cytokines (Hmgb1 and INF -y) during post- pneumonectomy lung regeneration, although most cytokines studied were unaffected by the procedure ... pneumonectomy using Affymetrix GeneChip micro- array technology. Samples were taken at four time points (6 hours, 1 day, 3 days and 7 days) post-pneumonectomy spanning the period during which...

Ngày tải lên: 12/08/2014, 14:20

... newly in vitro infected CD4 + lym- phocytes do not display the typical cellular features of genetic instability that characterize in vivo infected CD4 + clones. After having characterized in vitro ... [25]. Co-cultures were maintained f or 28 days in six-well plates in 4 ml of RPMI 1640 medium (Gibco, Paisley, United Kingdom) containing 100 U/ml of recombinant interleukin 2 in the...

Ngày tải lên: 12/08/2014, 23:23