Báo cáo y học: "odel-independent fluxome profiling from 2H and 13C experiments for metabolic variant discriminationm" pot

... through pentoseP pathway (ub) Oxaloacetate from TCA cycle Labeled CO 2 Pyruvate from malate (ub) Pyruvate from malate (lb) PEP from oxaloacetate Serine from glycine Glycine from serine ... component analysis automatically mapped several fingerprints to their metabolic determinants. The approach is flexible and paves the way to large-scale fluxome profiling of any biologic...

Ngày tải lên: 14/08/2014, 14:21

... specificity for non-B subtypes. However, for clade B viruses, only PSSM X4R5 and geno2pheno yielded good sensitivity and specificity when compared with other algorithms [11]. Our study findings ... ID's and their corresponding HIV genotype from partial sequences (gp41/p17/pol), its tropism by prediction and cell culture assay. AIDS Research and Therapy 2009, 6:27 http://...

Ngày tải lên: 10/08/2014, 05:21

... factors for postictal psychosis. J Neuropsychiatry Clin Neurosci 2001, 13(4):492-499. 14. Adachi N, Matsuura M, Hara T, Oana Y, Okubo Y, Kato M, Onuma T: Psychoses and epilepsy: are interictal and ... lateral temporal hyperperfusion as assessed by SPECT in postictal psycho- sis [19], and they thereby argue against the Todd's paraly- sis hypothesis which might predict hypoperfus...

Ngày tải lên: 08/08/2014, 21:20

... cancer surgery in day care, namely anaesthesiologists, surgical oncologists, and breast care nurses. The Dutch Society for Anaesthesiology and the Dutch Society for Surgical Oncology supplied the ... preoperatively on the day of surgery 5. Patients should be visited by the breast cancer nurse preoperatively on the day of surgery 6. Patients should receive information from the surgeo...

Ngày tải lên: 11/08/2014, 05:21

... biopsy showed portal inflammatory infiltrate, spotty necrosis, vacuoles of macro- and micro-vesicular steatosis, acidophil and foamy hepatocytes degeneration with organelles clumping, poorly formed ... GC and SC participated in conceiving the study, in the acquisition of data and revised the manuscript. LB and MG analyzed the liver biopsy and revised the manuscript. CT conceived t...

Ngày tải lên: 11/08/2014, 10:22

... Eli Lilly and Company, Indianapolis, Indiana, USA. Authors’ contributions Concept and design WY, YZ, RR, RWS; acquisition of data WY, YZ, RR; analysis and interpretation of data WY, YZ, RR, RWS; ... interests This study and its report were supported and fully funded by Eli Lilly and Company (Indianapolis, Indiana), which had a role in study design; data acquisition and analysis;...

Ngày tải lên: 11/08/2014, 16:23

... of 23.9–70.0% for shock, 9.5–35.0% for renal failure, 0.3–37.5% for CNS dysfunction, 4.1–27.9% for liver failure, 5.5–15.0% for DIC, 2.8–21.8% for ARDS, and 19.3–49.1% for 28-day mortality rate. Figure ... practices prob- ably also play roles. Uncertainty may be especially problem- atic in conditions such as sepsis, in which mortality is high, and clinicians strongly want to...

Ngày tải lên: 12/08/2014, 19:22

... energy). The ROC curves for coughs from each gender are shown in Figure 5. The point on the curve which yielded an equal sensitivity and specificity was 98% for coughs from female subjects and ... analyzing voluntary coughs was capable of achieving an overall classification performance of 94% and 97% for identifying abnormal lung physiology in female and male subjects, respe...

Ngày tải lên: 13/08/2014, 08:20

... ele- ments and potential aneuploidy associated genes. Micro- array analysis was performed utilizing cytoplasmic mRNA from both cells and the Affymetrix Murine Genome U74A Array. Analysis was performed ... contrib- utes to the activity of the cyclic AMP (cAMP) pathway and physically interacts with the adenylyl cyclase Cyr1p/ Cdc35p, where a Gα subunit-type protein called Gpa2p and th...

Ngày tải lên: 13/08/2014, 09:20

... human immunodeficiency virus type 1 Env-mediated membrane fusion by viral protease activity. J Virol 2004, 78:1026-1031. 33. Abrahamyan LG, Mkrtchyan SR, Binley J, Lu M, Melikyan GB, Cohen FS: The cytoplasmic ... gp120 then lysed with NP40 lysis buffer (0.5% NP40, 150 mM NaCl, 50 mM Tris pH 8) on ice for 10 minutes. Clarified lysates were assayed for gp120 con- tent by SDS-PAGE and West...

Ngày tải lên: 13/08/2014, 09:20