Báo cáo y học: "Hidden localization motifs: naturally occurring peroxisomal targeting signals in non-peroxisomal protein" pdf
Báo cáo y học: "Hidden localization motifs: naturally occurring peroxisomal targeting signals in non-peroxisomal protein" pdf
... carboxyl termini of a set of definitely non -peroxisomal proteins with
predicted peroxisomal targeting signals interact with the peroxisomal matrix protein receptor
peroxin 5 (PEX5) in a yeast ... PTS1-like carboxyl terminus is
critical
The fact that the peroxisomal translocation machinery fails to
import naturally occurring mature proteins carrying PTS1
signals into perox...
Báo cáo y học: " Antioxidant components of naturally-occurring oils exhibit marked anti-inflammatory activity in epithelial cells of the human upper respiratory system" pdf
... that
proinflammatory signaling was abrogated in the nasal
mucosa by the treatment, possibly through mechanisms
involving increased intracellular antioxidant activity lead-
ing to reduced inflammatory drive. In ... the airway lumen as early as 1 hr following exposure
[47] suggesting very ra pid initiation of pro-inflammatory
signaling. In the present study, the effectiveness of the oil...
Báo cáo y học: " E box motifs as mediators of proviral latency of human retroviruses" pdf
... proteins, thereby increasing proviral
transcription. Finally, a phylogenetic study encompassing several subtypes of these two human
retroviruses underlines that these E box motifs have recently ... protein, to the 3' E box of HIV-1 LTR [4,5].
Recently, the binding of AP-4 (and possibly other bHLH
proteins) to the 3' E box was found to exclude the binding
of TATA-binding proteins ......
Báo cáo y học: " Identification of NCAM that interacts with the PHE-CoV spike protein" pdf
... Anti-NCAM antibody inhibition of PHE-CoV binding to N2a cells. PHE-CoV binding assay using various concentrations of anti-
NCAM antibody. The 10 μg/ml anti-NCAM antibody inhibited PHE-CoV binding to N2a ... N2a cells by 75%. With the increased anti-NCAM antibody
concentration in the blocking, the inhibition rate increased accordingly. The 25 μg/ml anti-NCAM antibody inhibited PHE-CoV bindin...
Báo cáo y học: "The complete genome of klassevirus – a novel picornavirus in pediatric stool" pdf
... (500–800 nt) containing an
internal ribosome entry site (IRES), a single ORF encoding
a polyprotein that is proteolytically processed, and a short
3' UTR followed by a polyA tail [1]. Major ... to amplify any klassevirus or kobu-
virus found klassevirus only in two young children from
the same family. The virus was present in relatively high
copy number in both samples, suggesting...
Báo cáo y học: "Crystalloids versus colloids for goal-directed fluid therapy in major surgery" pdf
... but
remained unchanged in the other two groups. Likewise, tissue
oxygen tension in the intestine increased by 30% in the GD-C
group but remained unchanged in the GD-RL group and
decreased by 18% in ... study, we hypothesize that goal-directed colloid
fluid therapy in the setting of major abdominal surgery
increases intestinal microcirculatory blood flow and tissue oxy-
gen tension...
Báo cáo y học: " Increased blood flow by insulin infusion targeting normoglycemia in patients with severe sepsis: friend or foe" ppt
... between insulin signaling and
hyperglycemia on in ammation and blood fl ow is an
interesting one, which is important to take into account
when analyzing results of studies on the topic. In this ... if the increase in forearm fl ow is indeed
evoked by the more intensive insulin therapy, it
corroborates extensive data from basic research in in
vitro cellular models [2-4] and from in...
Tài liệu Báo cáo Y học: Intracellular localization and transcriptional regulation of tumor necrosis factor (TNF) receptor-associated factor 4 (TRAF4) pdf
... cytoplasmic retention of TRAF4. Interestingly, it has
been recently shown that the oncogenic serine–threonine
kinase Pim-1 induces translocation of the TRAF4-interact-
ing protein-sorting Nexin ... lysates containing cytoplasmic
(C) and nuclear proteins (N) were analyzed by Western blotting.
TRAF4 was detected using an affinity-purified polyclonal anti-
(TRAF4) goat Ig recognizing a carboxy-term...
Báo cáo Y học: Immunohistochemical localization of guinea-pig leukotriene B4 12-hydroxydehydrogenase/15-ketoprostaglandin 13-reductase pdf
... lysosomal enzymes [1,26].
LTB
4
is produced mainly in leukocytes, but also in various
tissues [12–17]. LTB
4
is inactivated by omega-oxidation to
yield 20-hydroxy-LTB
4
and 20-carboxy-LTB
4
in ... identity between guinea-
pig and porcine enzymes is 78% at the amino-acid level
as shown in Fig. 1B. The amino acids in the putative
NAD
1
/NADP
1
binding domain [22] are well conserved i...
Báo cáo y học: "Extracellular localization of galectin-3 has a deleterious role in joint tissues" docx
... resulted in an inhibitory effect closer to
50% (Figure 6). Vitamin D
3
-stimulated osteocalcin production
tended to be inhibited by genistein (35%) and SB202190
(40%), indicating that tyrosine kinases ... respectively), indicating that neither
protein kinase A nor protein kinase G are involved in gal-3-
inhibited osteocalcin production. This result was confirmed by
the fact that gal-3 alo...
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