Báo cáo y học: "Insertion bias and purifying selection of retrotransposons in the Arabidopsis thaliana genome Vini Pereira" ppsx

... positively corre- late). Consistent with my results, the same study supports a model of purifying selection against insertions in intergenic DNA, by inferring that they are less likely to be found ... and Gypsy-like), as initial mining of the A. thaliana genome revealed that Athila elements have been particularly successful in colonizing it. Their copy number is roughly...

Ngày tải lên: 14/08/2014, 14:21

... we investigated the MAP kinase and IκB kinase signaling pathways by western blot (Figure 3a). Interestingly, piperine did not significantly affect the IκB kinase signaling pathway or the MAP kinase ... of the anti-inflammatory effects of piperineHistological evaluation of the anti-inflammatory effects of piperine. Paraffin sections of rat ankles were stained with hematox...

Ngày tải lên: 09/08/2014, 14:20

... quantification of axonal boutons afforded us a higher sensitivity in detecting differences in the present study. In the context of our finding, it is interesting to note that, a single polymorphism in the ... furnished by other pyramidal neurons, located both within the PFC and in other cortical areas [10-12]. The integrity of PFC functions therefore depends on th...

Ngày tải lên: 11/08/2014, 17:20

... subspecies. The results of the genetic analysis confirm our morphological observations and our tests of tentative hybridization and reinforce our hypothesis of the distinction of ... cross-breedings Owing to the cannibalism of males against females during ecdysis, only some cross-breedings were realized in the laboratory. The interspeci...

Ngày tải lên: 09/08/2014, 18:21

... mediated by point mutations with the YMDD motif at the catalytic center of the viral reverse transcriptase. With increase in the mutant viral load, patients can sustain further liver injury. The YMDD ... further research and understanding in this sector may bring exciting new information and better understanding of the natural history of HBV and supplement our...

Ngày tải lên: 02/11/2012, 11:17

Ngày tải lên: 03/11/2012, 11:11

... of cystatin F is hypothetical. Although most cystatins inhi- biting cathepsin L also inhibit cathepsin S, an inhibitory activity of cystatin F against cathepsin S has not yet been reported. The ... were partially purified by their affinity to Cm-papain, strongly indicating that the carbohydrate side chains do not affect the enzyme-binding properties of cystatin F and should, thus,...

Ngày tải lên: 21/02/2014, 01:21

... ±Birk protease inhibitors [5], metallothioneins [6], prothymosin a [7], a bacterial ®bronectin-binding protein [8], the brain protein a-synuclein together with the related proteins b-synuclein and c-synuclein ... elical conformation. There may also be some b strand in some of the proteins, espec ially b-andj-casein judging b y the well- de®ned negative ROA bands in these pro...

Ngày tải lên: 21/02/2014, 15:20

... mutant consisting mainly of the RING and zinc finger domains of TRAF4 were both localized predominantly to the nucleus. Passive nuclear localization of T4(259–470) can be ruled out as the TRAF domain of ... to the architecture of the N-terminal domain, TRAF1 is clearly distinct from all other TRAFs. While the N-terminus of TRAF2–TRAF6 contains a highly conserved RING...

Ngày tải lên: 21/02/2014, 15:20

... As both the E a of inactivation and the temperature at which the enzyme starts inactivating at a measurable rate increase from the apoenzyme to the Mn 2þ -containing enzyme, loss of the metal cofactor ... between the buffer and the enzyme by preincubating the enzyme–metal mixture at 30 8C for 30 min. Remaining activity was measured with glucose as the substrate in...

Ngày tải lên: 22/02/2014, 07:20