Báo cáo y học: "Variation in alternative splicing across human tissues" potx
Báo cáo y học: "Variation in alternative splicing across human tissues" potx
... Multisite
RNA binding and release of polypyrimidine tract binding
protein during the regulation of c-src neural-specific splicing.
Mol Cell 2000, 5:949-957.
61. Chan RC, Black DL: The polypyrimidine tract ... cis-
regulatory elements and trans-acting factors involved in tis-
sue-specific AS.
Results and discussion
Variation in the levels of alternative splicing in different
human...
Báo cáo y học: "Analysis of alternative splicing with microarrays: successes and challenges" docx
... experimentally induced intron reten-
tion in a number of genes containing introns. Yeakley et al.
[22] detected alternative splicing in six human genes using a
fiber-optic microarray platform. ... mRNA
processing in yeast using splicing- specific microarrays.
Science 2002, 296:907-910.
22. Yeakley JM, Fan JB, Doucet D, Luo L, Wickham E, Ye Z, Chee MS, Fu
XD: Profiling alternativ...
Báo cáo y học: "Variation in nocturnality and circadian activity rhythms between photoresponsive F344 and nonphotoresponsive Sprague Dawley rats" ppsx
... Strain differences in the pattern and intensity of
wheel running activity in laboratory rats. Experientia 1991,
47:593-598.
23. Siebert U, Wollnik F: Wheel-running activity rhythms in two
inbred ... Variation in circadian rhythms and nocturnality may, hypothetically, be related to or
independent of genetic variation in photoperiodic mediation of seasonal changes in physiology and...
Báo cáo y học: "Variation in red cell transfusion practice in the intensive care unit: a multicentre cohort study" pptx
... concentrations
during the first 10 days of intensive care unit (ICU) stay. There was an
average decrease of 16g/l in haemoglobin concentrations in all
patients admitted to the ICU over the 10-day monitoring interval.
Institution ... determine the degree of interinstitutional transfusion practice
variation and reasons why red cells are administered in critically ill patients.
Study desig...
Báo cáo y học: " Variation in conserved non-coding sequences on chromosome 5q and susceptibility to asthma and atopy" pot
... iden-
tifying SNPs.
Genotyping
The genotyping methods used in this study are described
in Additional File Table 2. In addition to four SNPs in or
flanking conserved sequences, we genotyped six ... (CNE-C) in the
IL4 gene, may influence susceptibility in combination
with other variation in IL4, or may merely be in LD with
other variation in the gene that influences susceptibi...
Báo cáo y học: "Variation in sepsis care: a wake-up call" ppsx
... be
explained in several ways. First, the interventions do not
affect outcome. Certainly, there is mounting evidence that
some of the studied interventions, such as application of the
pulmonary artery ... outcome.
Second, any beneficial effects are offset by unwanted side
effects. For example, better titration of care secondary to
information gained by pulmonary artery catheter use may be
of...
Báo cáo y học: "Variation in HIV-1 R5 macrophage-tropism correlates with sensitivity to reagents that block envelope: CD4 interactions but not with sensitivity to other entry inhibitors" pps
... Discovery of 4-ben-
zoyl-1-[(4-methoxy-1H-pyrrolo[2,3-b]pyridin-3-
yl)oxoacetyl]-2-(R)-methylpiperazine (BMS-378806): a novel
HIV-1 attachment inhibitor that interferes with CD4-gp120
interactions. ... binding
site, or both. Certainly brain-derived envelopes are more
likely to carry the N283 in the C2 CD4 binding site as
reported by Dunfee et al. [35] and confirmed by our group
Sensitivity...
Báo cáo y học: "Variation in the PaO2/FiO2 ratio with FiO2: mathematical and experimental description, and clinical relevance" pptx
... to shunt. Indeed, Riley and Cournand [20] recog-
nized in the 1950s that oxygenation problems should be
divided in this way. With the ability to identify two-parameter
models rapidly using pulse ... oximetry data [14] and simple clin-
ical methods [13], their clinical application seems timely.
Table 1
Numbers of patients changing disease group with increasing inspired oxygen fraction (FiO...
Báo cáo y học: "Variation in tissue-specific gene expression among natural populations" ppt
... A2
y F4 Cystathionine beta synthase Cystathionine-beta-synthase
z K11 Cold inducible RNA binding Cold inducible RNA-binding protein; (CIRBP) glycine-rich RNA binding protein;
aa F2 Hepatocyte ... popula-
Inconsistent - other metabolism
qq C7 Transketolase Transketolase
rr H8 Fatty acid binding 7 brain Fatty acid binding protein 7 brain (B-FABP)
ss A3 Fatty acid binding H6 Fatty acid binding...
Báo cáo y học: "Phylogenetically widespread alternative splicing at unusual GYNGYN donors" pot
... research interactions information
Genome Biology 2006, 7:R65
amino acid indels (intron phase 0: alanine, valine; phase 1:
arginine, glycine, serine; phase 2: arginine, glutamine, leu-
cine) and ... splicing noise. Con-
sistently, such subtle changes by alternative splicing may
result in functional differences for the two proteins. An
arginine insertion between two zinc fingers results...
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