Báo cáo y học: "Genomic and proteomic adaptations to growth at high temperature" potx

... research interactions information refereed research Opinion Genomic and proteomic adaptations to growth at high temperature Donal A Hickey* and Gregory AC Singer † Addresses: *Department of Biology, Concordia University, ... intra-genomic G+C heterogeneity in human and chicken is mainly due to strand-symmetric directional mutation pressures: dGTP-oxidation and symmetric...

Ngày tải lên: 14/08/2014, 14:21

... systemic lupus erythematosus (SLE) and is one of its major causes of death, an observation first made more than 20 years ago by Urowitz [1]. Coronary artery disease develops in 6–9% of SLE patients ... electron-beam computed tomography, and thal- lium perfusion scanning, and one autopsy study, suggest that symptomatic disease might be the tip of the iceberg. The true incidence could be...

Ngày tải lên: 09/08/2014, 01:22

... publication bias makes it unclear how many studies fail to identify a causal locus by exome sequencing. Non-allelic heterogeneity, regulatory variation and structural variation underlying ... underlying genotypes. Bayesian posterior probabilities can then be calculated for each potential genotype [12]. Two popular tools for SNP discovery in NGS data that are easily incorporated in...

Ngày tải lên: 09/08/2014, 23:20

... contributing significantly to high morbidity and mortality [22]. In this study, RTCs were the most common cause of inju- ries and the majority of these were due to motorcycle accidents, an emerging ... morbidity. Esti- mates of length of hospital stay are important for finan- cial reasons, and accurate early estimates facilitate better financial planning by the payers. The overall...

Ngày tải lên: 10/08/2014, 09:23

... contributed to study design, data collection, analysis and manuscript preparation; RF contributed to study design and data analysis; NL contributed to data collection and final manuscript preparation; MR contributed ... that loneliness and depression may act syner- gistically to diminish well being [36]. Our study has also shown a moderately high correlation between loneline...

Ngày tải lên: 11/08/2014, 16:22

... ATP synthesis, thereby enabling an a thlete to train harder to promote greater muscular hypertrophy via increased myosin heavy chain expression; possibly due to an increase in myogenic regulatory ... elucidate such hypotheses. Background The combination of creatine monohydrate supplementa- tion (CR) and resistance training has been shown to synergistically accentuate muscle fiber hy...

Ngày tải lên: 11/08/2014, 23:21

... known to attract and activate leukocytes and plays a major role in the initiation and maintenance of inflammatory responses [7]. In particular, IL-8 is a potent chemoattractant for neutrophils and ... analyzed the phos- phorylation of VASP, known to be phosphorylated at Ser- 157, a PKA-specific site [49], by using a VASP-specific anti- body that recognizes both phospho-VASP (upp...

Ngày tải lên: 12/08/2014, 14:20

... dopamine-resistant patients (survival 16%) [7]. At the least, the metabolic response can be evaluated by the ability to produce lactate. During septic shock, lactate production may be related not only to a hypoxic ... receptors are β 2 receptors. We recently demonstrated in low-flow (hemorrhagic) and normal -to- high- flow models of shock (endotoxin and peritonitis) that lactate pr...

Ngày tải lên: 13/08/2014, 10:20

... simultaneously by categories of pattern-dataset similarity and pattern differentiation outcome grouped by incremental combination of the Four Examinations Pattern-dataset similarity, S* Total Outcomes ... conver- sely, a manifestation profile may indicate several ZFSPs. Patterns, as related to illnesses [16], may be associated or dissociated to other patterns by factors such as: man- if...

Ngày tải lên: 13/08/2014, 14:20

... students after they had been told that their par- ticipation was completely voluntary in nature, and that they could discontinue their involvement at any time. Anonymity and confidentiality of responses ... send you to your room). Your parents take away privileges or ground you? Your parents threaten to spank or hit you but did not actually do it. Your parents shout, yell or scream...

Ngày tải lên: 13/08/2014, 18:21