Báo cáo sinh học: " Should genetic groups be ﬁtted in BLUP evaluation? Practical answer for the French AI beef sire evaluation" doc

... overestimated by including genetic groups in the evaluation. In that case, animals belonging to the overestimated groups will be chosen to the detriment of animals belonging to the underestimated groups ... depend mainly on the accuracy of the evaluationand, to a certain extent, on the selection process, i.e. whether selection is be- tween groups or within-group. In brief, the inclusion of genetic groups ... by in- cluding ﬁxed genetic groups when ∆G reached 0.3σa. The selection bias in the models with ﬁxed genetic groups decreased when the genetic diﬀerencebetween groups increased.When comparing...

Báo cáo sinh học : " Is genetic diversity really higher in large populations" ppsx

... and the number of reproducing individuals in the population. The latter is usually termed the effectivepopulation size (Ne), and is almost always less than the total population size. These ... mutation rate. A recent study in BMC Evolutionary Biologyshows that variation in the rate of mutation rather than in population size is the main explanation for variations in mtDNA diversity observed ... argued that the non-recombining nature ofmtDNA makes its diversity prone to be shaped by naturalselection for new and beneficial variants - eradicating, or atleast reducing, a correlation between...

Báo cáo sinh học: " Medical education and research environment in Qatar: a new epoch for translational research in the Middle East" pptx

... residency spots in their fields of inter-est at excellent institutions in the US (See Table 6). Out of17 graduating stude nts, 11 ( 65%) are pursuing postgraduateresidency training in the US. Four ... establishing sus-tainable training programs/courses for students andphysicians.3. Developing and nurturing viable, collaborati ve part-nerships with local and international institutions tofurther ... preventing strategies in combating NCDs. These strategies will not only reduce the incidence of these diseases but also reduce pain and allevi-ate suffering associated with them. An outline of...

Báo cáo khoa học: Alternative splicing produces an H-protein with better substrate properties for the P-protein of glycine decarboxylase doc

... °C in the linear responserange for 20 min (varying glycine) or 30 min (varyingH-protein). Rates obtained without substrate were sub-tracted, and kinetic parameters were calculated by nonlin-ear ... H-protein differs from the naturally occur-ring Arabidopsis H-protein only by the insertion oftwo additional alanyl residues near the N-terminus.Kinetic analysis of the these two H-proteins fully ... with saturating normal FtGLDH. In order to determine whether this ﬁnding can be generalized beyond Flaveria H-proteins, we engineereda splice variant of the H-protein AtGLDH1 from the C3plant...

Báo cáo y học: "Capturing real-life patient care in psoriatic arthritis and its risks: the challenge of analysing registry data" docx

... lowerbaseline, even if the patients have reached the sameunsatisfying endpoint. This might, at least in part, explain thisparadox. In RA, therapy steered by an index has becomemore and more a mainstay ... terminations and thenat only those terminations for the reason of ineffectivenessand terminated for the reason of toxicity. This was done bycensoring patients with treatment terminations other ... reached the end of observation without reaching the outcome [7]. In this way, the observed period that was event-free (that is, no ineffectiveness of the drug) can inform the analysis. In contrast...

báo cáo sinh học:" "I won''''t be staying here for long": a qualitative study on the retention of migrant nurses in Ireland" ppt

... nurses had been involved in the internationalrecruitment "game" for some time and were acutely awareof the need to look after their own interests and maintain the integrity of their family ... consideration for migrantnurses in the decision-making process; this was true for both married and single respondents. If they lived apartfrom family members, the focus was on maintaining the remittance ... decidingwhether to stay or to leave.Reasons to remain in IrelandMost of the 10 respondents who planned to remain in Ire-land for the foreseeable future sought to do so becausethey felt that they...

Báo cáo sinh học: "Detailed genetic analysis of hemagglutinin-neuraminidase glycoprotein gene in human parainfluenza virus type 1 isolates from patients with acute respiratory infection between 2002 and 2009 in Yamagata prefecture, Japa" docx

... classified into different clusters from the reference strains. The number of detected strains in each cluster on the phylogenetic tree was as follows: cluster 1, 84 strains including strains isolated ... based on the nucleotide sequences by the NJ method is shown in Figure 1. The enlarged cluster shows the HPIV1 strains. The phylogenetic tree containing the isolated and reference strains was ... of the minor clusters in the trees. The tree was constructed by neighbor-joining analysis with labeling of the branches showing at least 70% bootstrap support. The representation of the strain...

Báo cáo sinh học: "Modeling genetic imprinting effects of DNA sequences with multilocus polymorphism data" ppsx

... to be imprinted for PreInt49tot, a pain sensitivity trait to heatstimuli at 49°C before drug administration, leading todifferent levels of pain sensitivity between the patientswhen they inherit ... setting the effect being tested to be equal tozero. For example, under the triallelic model, the nullhypothesis for testing the imprinting effect of the haplo-typesis expressed as In practice, ... Three traits of pain sensi-tivity to heat were tested with a procedure described byFillingim [22], and they are the average pain rating for heat stimuli at 49°C (PreInt49tot), the increase in heatpain...

Báo cáo y học: "Should fresh blood be recommended for intensive care patients" potx

... RBC, red blood cell.Competing interests The author declares that he has no competing interests.Author details1Inserm, Unité de Recherche en Épidémiologie Systèmes d’Information et Modélisation ... Faubourg Saint Antoine, 75012 Paris, France. 2UPMC Univ Paris 06, 184 rue du Faubourg Saint Antoine, 75012 Paris, France. 3Assistance Publique - Hôpitaux de Paris, Hôpital Saint-Antoine, Service ... countries but was performed in only 86% of the transfusions in this study.Given the design of the study, it is not possible to state that there is a cause-and-eﬀ ect relationship between older...

Báo cáo sinh học: "A genetic epidemiological model to describe resistance to an endemic bacterial disease in livestock: application to footrot in sheep" potx

... showing clinical signs, while continuing to be infectious in the SELDCRS model The rate at which infectious animals that no longer show clinical signs of the disease stop being infectious in the ... corre-sponding to p [13]. For the case where the number of healthy animals availa-ble for breeding exceeds the number required for selec-tion, and again disregarding information from relatives, the ... during the course of its infectious period. The equivalent in the SELIRS model is the number of second-ary infections due to a single infectious animal, for the time period over which the infectious...

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