Báo cáo sinh học: "Inferring causal phenotype networks using structural equation models" pps

... 2009, 87:1883-1887. doi:10.1186/1297-9686-43-6 Cite this article as: Rosa et al.: Inferring causal phenotype networks using structural equation models. Genetics Selection Evolution 2011 43:6. Submit your next ... 43:6 http://www.gsejournal.org/content/43/1/6 Page 8 of 13 REVIE W Open Access Inferring causal phenotype networks using structural equation models Guilherme...

Ngày tải lên: 14/08/2014, 13:21

... time-consuming, regulatory networks are commonly inferred from gene- expression data. Various computational models, such as Boolean networks [1], Bayesian networks [2], dynamic Bayesian networks (DBNs) ... of networks, we use the leaf networks to create simulated expression data and use our preferred net- work inference method to reconstruct networks from the expression data. The...

Ngày tải lên: 12/08/2014, 17:20

... not for citation purposes) Human Resources for Health Open Access Research Paris on the Mekong: using the aid effectiveness agenda to support human resources for health in the Lao People's ... aid- effectiveness approaches to sector level. Methods: The research adopted a case study approach using mixed research methods. It draws on a quantitative analysis of human resources for heal...

Ngày tải lên: 18/06/2014, 17:20

... PCR amplifications occur simultaneously. Using this method, we have successfullydetected and partially sequenced 3 separate viruses in human plasma without using virus-specific reagents (i.e., Adenovirus ... Respiratory Syncytial Virus B), using the novel approach of random multiplex (RT)-PCR of purified viral nucleic acids. The detection was accomplished in 7 hours using only a micro...

Ngày tải lên: 18/06/2014, 18:20

... (Beograd) 54 [35] Fochi, M: Functional equations in A-orthogonal vectors. Aequationes Math. 38, 28–40 (1989) [36] Szab´o, Gy: Sesquilinear-orthogonally quadratic mappings. Aequationes Math. 40, 190–200 ... Conditional function equations and orthogonal additivity. Aequationes Math. 50, 135–142 (1995) [38] Kenary, HA: Non-Archimedean stability of Cauchy-Jensen type functional equation. Int. J....

Ngày tải lên: 18/06/2014, 22:20

... have learned from the cell-based assays and validate them in vivo, either using defined existing mutations or by trying to generate them using classical methods or a promising gene-knockout methodology. ... team recorded all visible changes three days after introduction of the RNA, using automated microscopy. Around 16% of the genes gave visible phenotypes in at least one of the two cel...

Ngày tải lên: 06/08/2014, 18:20

... interesting structure within the data. Speculating a little further, the work opens up the intriguing prospect of using quantitative information to help refine and further validate the qualitative models themselves. ... conclusion, the work by Zhang et al. [6] provides us with a clear message: a carefully designed study using Gene Ontology and quantitative expression profiles can reveal f...

Ngày tải lên: 06/08/2014, 18:21

... were not confusing enough, emerging complexities are sure to muddy the waters further. For example, there is evidence that it is not just a person’s genome that helps determine their obesity phenotype, ... experiences as well) not only affects their own body-weight phenotype, but can also (in the case of women) affect the body-weight phenotype of their offspring through epigenetic mechani...

Ngày tải lên: 06/08/2014, 18:21

... ppooppuullaattiioonnss?? Hans Ellegren Address: Department of Evolutionary Biology, Uppsala University, Norbyvägen 18D, SE-752 36 Uppsala, Sweden. Email: Hans.Ellegren@ebc.uu.se Students of population genetics

Ngày tải lên: 06/08/2014, 19:20

Ngày tải lên: 06/08/2014, 19:20