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Báo cáo sinh học: "Comparing the retention mechanisms of tandem duplicates and retrogenes in human and mouse genomes" pdf

Báo cáo sinh học:

Báo cáo sinh học: "Comparing the retention mechanisms of tandem duplicates and retrogenes in human and mouse genomes" pdf

... retained in the mouse genome. In our dataset, there are both more tandem duplicates and more retrogenes in the mouse genome. Totest if the excessive duplicates are really created in the mouse lineage, ... genome, and 1,802 tandem duplicates and 680 retrogenes in the mouse genome. The highernumber of tandem duplicates than retrogenes in bothgenomes implies a higher gene duplicability for tandem duplicates. ... further com-pare the underlying retention mechanisms, we attemptedto investigate the tandem duplicates arising from unequalcrossing-over and retrogenes arising from retroposition in human and...
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báo cáo sinh học:

báo cáo sinh học:" Understanding the ‘four directions of travel’: qualitative research into the factors affecting recruitment and retention of doctors in rural Vietnam" doc

... affecting recruitment and retention of doctors in rural areasThi s section presents the findings of the interviews, fol-lowing the themes laid out in Table 2.Motivation to join the professionMedicine ... or other methods of fos-tering professional development and peer standing.One theme which stands out is the complexity of funding s ources for doctors in Vietnam, and the extentto which these ... with the current condi-tions. The main reasons given were stability of theirlives, a n interesting job, and being close to their hometown and f amilies. Stable lives, including work and income,...
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Báo cáo khoa học: Understanding the complex mechanisms of b2-microglobulin amyloid assembly potx

Báo cáo khoa học: Understanding the complex mechanisms of b2-microglobulin amyloid assembly potx

... gain a more detailed understanding of the kineticfolding mechanism of b2m and the role of differentpartially folded species in linking the folding and aggregation energy landscapes, Jahn and ... analysed the folding and unfolding kinetics of b2munder an array of conditions, including analysis of the folding mechanism of the variant P32G. Using globalanalysis of the resulting kinetic ... prop-erties of P32G using NMR suggested large conforma-tional changes involving residues in the BC- and FG-loops, the D-strand and the N-terminal region of the protein that presumably arise from the...
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báo cáo sinh học:

báo cáo sinh học:" Empowering the people: Development of an HIV peer education model for low literacy rural communities in India" pdf

... and invited them for subsequent training. The duration of the training was six, four and two days for OW, PHE and bar-bers, respectively. All trainings were performed in the native language of Tamil. ... womendropped out during the training program because of objections to its sexual content. Of the remaining 137who completed the training, the average pre- and post-testscores were 42% and 82%, respectively ... declare that they have no competing interests.Authors' contributionsKVR, PM, KK, VC and DS participated in the initial con-cept, the design of the study and the development of the IEC materials....
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báo cáo sinh học:

báo cáo sinh học:" Costing the scaling-up of human resources for health: lessons from Mozambique and Guinea Bissau" docx

... the real cost of training in the health sector, including initial and on- the job training (or continuous medical education), post-graduate training and scholarships, and; (c) to calculate the ... train abroad. In Mozam-bique, the methodology also included the investmentcosts of expanding the physical training network. Thiswas not possible in Guinea Bissau as, at the time of the costing ... participated in the study conception and design, and in drafting and editing the manu-script. PF participated in the fieldwork and in editing the manuscript. Allauthors read and approved the final...
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báo cáo hóa học:

báo cáo hóa học: " Comparing the immunosuppressive potency of naïve marrow stromal cells and Notch-transfected marrow stromal cells" docx

... either SB623 cells or MSCs in the absence of exogenous cytokines. As Th1 cansecrete bot h IFN-g and IL-10, we performed dual stain-ing for these two cytokines to determine if the inclusion of ... twowashes in PBS/2% F BS, cell pelle ts were resuspended in 200 ul of PBS/2% FBS and divided into two tube s, onefor staining with phycoerythrin (PE)-conjugated IgG(control) and the other for staining ... skewed the activated immune secretome.We demonstrate that the inclusion of either MSCs orSB623 cells resulted in robust skewing of the activatedimmune secretome profile with more than 20% of the cells...
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Báo cáo hóa học:

Báo cáo hóa học: " Developing the dielectric mechanisms of polyetherimide/multi-walled carbon " pot

... compatibility between the PEI matrix and the functionalized MWNTs, caused by the strong interactions between the carboxyl and hydroxyl groups of the MWNTs, and the N and O of the PEI molecules [11]. ... models of both composites were established using the two mixing rules. In addition, the theoretical bases of the two mixing rules were used to explain the measured results for the PEI/MWNT and ... results. These outcomes indicate that as the MWNT content increased, the degree of parallel connection in the microstructures of the PEI/MWNTs also increased, whereas the degree of series connection...
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Báo cáo sinh học:

Báo cáo sinh học: "Deciphering the genetic code of morphogenesis using functional genomics" pdf

... translate the information contained in these data sets into meaningful biological insight. The study by Zúñiga et al. [7] highlights the value of integrating information from temporal and spatial ... each other to coordinate their behavior with other cells and tissues in the embryo. To elucidate the molecular mechanisms underlying these processes, an essential step is to identify the extracellular ... between cells and the transmembrane receptors that detect and interpret these signals and translate them into cell shape and behavior.Using suppression subtractive hybridization (SSH) and micro...
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Báo cáo y học:

Báo cáo y học: "Quantifying the major mechanisms of recent gene duplications in the human and mouse genomes: a novel strategy to estimate gene duplication rates" docx

... 700 in human and 857 in mouse (cor-responding to scenario 1), and 585 in human and 727 in mouse (corresponding to scenario 2). We obtained the lowerlimits by keeping only the pair that has the ... function of Ks were plotted in R [46] in both two-copy gene families and in the entire genome. The interval of the data points in terms of Ks of the curves is 0.01.Because initially genes are singletons ... discardedgenes encoding proteins shorter than 50 amino acids toensure annotation quality and obtained 22,598 human genes and 24,064 mouse genes. Of these, 8,312 in human and 8,105 in mouse are single-copy...
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