a textbook of modern toxicology phần 5 ppt

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Ngày tải lên: 26/01/2014, 08:20

... proce- dures (SOPs), quality assurance/quality control manuals (QA/QC manuals), procedural manuals, analytical method files, and laboratory information management systems A Textbook of Modern Toxicology, ... procedures are used to maintain a measurement system (i.e., a gas chromatograph) in a statistically satisfactory state to ensure the production of accurate and reliable da...

Ngày tải lên: 16/03/2014, 11:43

... * Sử dụng khoảng trống Bài 2 - Format, page layout and intonation of e-mails (Định dạng, cách trình bày trang và ngữ điệu của e-mail )-phần2 >>EXTREME!!<< EMPHASIS ... guess what? I GOT THE JOB!!!! :-D :-D !! SUMMARY (TÓM TẮT) Thật sự rất khó để biểu thị cảm xúc qua một đoạn thư ngắn như e-mail, tuy nhiên các bạn vẫn có...

Ngày tải lên: 12/07/2014, 01:20

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Ngày tải lên: 22/07/2014, 04:21

... AUG GU AUG UUU UAA AAUAA AAAAAAAA 3' AG UUU GU AG UAA AAUAA AAAAAAA AG TTT TAA AATAAGT AG Figure 2.2 Transcription, mRNA processing, and translation. DNA sense strand is designated by bold ... 2,3,7,8-terachloro-dibenzodioxane (TCCD) Induction of CYP 1A1 and 1B1 H 114 E Rat hepatoma Hepatocyte Polychlorinated biphenyls (PCBs) Induction o f CYP 1A1 HepG2 Human hepatoblastoma Hepatocyt...

Ngày tải lên: 14/08/2014, 11:21

... clams, and other bivalves of the cold and warm temperate areas of the Atlantic and Pacific Oceans, mainly in Japan and Europe. Only two cases of DSP have been documented in North America. Ciguatera ... the hands and arms, perforation of the nasal septum (probably caused by chromic acid), inflammation of the larynx and liver, and bronchitis. Chromate is a carcinogen causing bronchoge...

Ngày tải lên: 14/08/2014, 11:21

... by a peroxidase that uses prostaglandin G as a substrate. In at least some of these cases, the identity of this peroxidase has been established as a prostaglandin synthase. Many of the reactions ... depots. The antimalaria drug quinacrine accumulates due to reversible intracellular binding, and the concentration in the liver can be several thousand times that of plasma. Another...

Ngày tải lên: 14/08/2014, 11:21

... Examination of the term placentas of smoking human mothers revealed a marked stimulation of aryl hydrocarbon hydroxylase and related activities—remarkable in an organ that, in the uninduced state, ... desaturated fatty acids are highly susceptible to free radical attack, neighboring fatty acids are readily affected, and the initial metabolic transformation results in a cas- cade of...

Ngày tải lên: 14/08/2014, 11:21

... MUTAGENICITY Mutagens are chemical and physical agents that are capable of producing a mutation. Mutagens include agents such as radiation, chemotherapeutic agents, and many car- cinogens. A mutation ... cell/hypoxanthine-guanine phosphoribosyl transferase assay, the mouse lymphoma a ssay, the mammalian trans- formation assay, sister chromatid exchange, and the chromosome aberration a...

Ngày tải lên: 14/08/2014, 11:21

... signaling hormones along the cascade (i.e., hypothalamic–pituitary–gonadal axis), and sometimes, a terminal target organ of the signaling pathway (i.e., hypotha- lamic–pituitary–gonadal–hepatic axis). Endocrine ... such as gamma-glutamyl transpeptidase, alkaline phosphatase, and aromatic acid decarboxylase are more preva- lent in cerebral microvessels than in nonneuronal capillaries. Most...

Ngày tải lên: 14/08/2014, 11:21

... 2, and 3 days. Grading is subjective and based on the appearance of the cornea, particularly as regards opacity; the iris, as regards both appearance and reaction to light; the conjunctiva, as ... exposures. IgE acts as a mediator of allergy and par- asitic immunity. IgA is found in secretions such as mucous, tears, saliva, and milk, as well as serum, and acts locally to block entrance...

Ngày tải lên: 14/08/2014, 11:21

... probably unattainable with birds or wild mammals, even through bobwhite quail and mallards are easily reared in captivity. The genetics of the birds and mammals used are much more variable than are ... environmental contaminant is applied to the leaves of the terrestrial plant sorghum (Sorgum halpense), and then salt marsh caterpillars (Estigmene acrea) are placed on the plants. The larva...

Ngày tải lên: 14/08/2014, 11:21

... substance on a test organism as compared with the effect of a standard preparation of a basic toxicant. Although bioassay has many drawbacks, particularly lack of specificity, it can provide a rapid analysis ... very stagnant conditions are encoun- tered in the water or air. Modeling the transport of a chemical in air is particularly difficult because of the high spatial and...

Ngày tải lên: 14/08/2014, 11:21

... mating and migration habits) are considered. Finally, many extrapolation methods are limited by the availability of suitable databases. Although these databases are generally largest for chemical stressors ... human and animal use, and requires proof of both safety and efficacy. This act contains the Delaney Amendment, which states that food additives that cause cancer in humans or animals...

Ngày tải lên: 14/08/2014, 11:21

... administrators, and other JAD members; therefore, a very informal setting is our preference. The formality should come from the fact that there will be a go or no-go decision made on the architecture of the ... technology organization, and all the processes that make these up. There are many different ways of calculating the amount of risk, and we will cover some...

Ngày tải lên: 14/08/2014, 17:21